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Children
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Recent Advances in Hepatobiliary and Pancreatic Surgery in Children
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Recent Advances in Hepatobiliary and Pancreatic Surgery in Children

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Surgery".

Deadline for manuscript submissions: closed (5 January 2024) | Viewed by 6753

Special Issue Editors

Prof. Dr. Piotr Kaliciński

E-Mail Website
Guest Editor
Department of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute, 04-730 Warszawa, Poland
Interests: hepatobiliary surgery in children; gastrointestinal surgery in children; pediatric solid tumors; congenital malformations and neonatal surgery; abdominal organ transplantation in children (liver, kidney, intestine, multiorgan)
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Mark Davenport

E-Mail Website
Guest Editor
Department of Pediatric Surgery, Kings College Hospital, London SE5 9RS, UK
Interests: biliary atresia; choledochal malformation

Special Issue Information

Dear Colleagues,

Hepatobiliary and pancreatic surgery have always been considered the domain of general surgeons, but are becoming increasingly common in the practice of pediatric surgeons. We therefore encourage you to publish and share your experience in any aspect of hepatobiliary and pancreatic surgery in children, encouraging the exchange of knowledge among surgeons, as well as pediatricians, pediatric gastroenterologists, and oncologists. This Special Issue is open for papers on hepatobiliary and pancreatic trauma, congenital malformations, acquired diseases, inflammatory diseases, benign and malignant tumors as well as postsurgical complications including post-liver-transplantation problems. We invite papers on the use of minimally invasive surgical techniques including robotic surgery and radiological interventions, as well as intraoperative tools which enhance the safety and effectiveness of surgery.

Prof. Dr. Piotr Kaliciński
Prof. Dr. Mark Davenport
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric hepatobiliary diseases
  • pediatric hepatobiliary surgery
  • pediatric pancreatic diseases
  • pediatric pancreatic surgery
  • congenital hepatobiliary malformations
  • hepatobiliary tumors in children
  • pancreatic tumors in children
  • pediatric hepatobiliary trauma
  • pediatric pancreatic trauma
  • minimally invasive surgery

Published Papers (4 papers)

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Research

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8 pages, 1124 KiB  
Article
Choledochal Cyst Excision in Infants—A Retrospective Study
by Adam Kowalski, Grzegorz Kowalewski, Piotr Kaliciński, Katarzyna Pankowska-Woźniak, Marek Szymczak, Hor Ismail and Marek Stefanowicz
Children 2023, 10(2), 373; https://doi.org/10.3390/children10020373 - 14 Feb 2023
Cited by 3 | Viewed by 2126
Abstract
A choledochal cyst is a rare malformation primarily diagnosed in children. The only effective therapy remains surgical cyst resection followed by Roux-en-Y hepaticojejunostomy. Treating asymptomatic neonates remains a point of discussion. Between 1984 and 2021, we performed choledochal cyst (CC) excision in 256 [...] Read more.
A choledochal cyst is a rare malformation primarily diagnosed in children. The only effective therapy remains surgical cyst resection followed by Roux-en-Y hepaticojejunostomy. Treating asymptomatic neonates remains a point of discussion. Between 1984 and 2021, we performed choledochal cyst (CC) excision in 256 children at our center. Out of this group, we retrospectively reviewed the medical records of 59 patients who were operated on under one year of age. Follow-up ranged from 0.3 to 18 years (median 3.9 years). The preoperative course was asymptomatic in 22 (38%), while 37 patients (62%) had symptoms before surgery. The late postoperative course was uneventful in 45 patients (76%). In symptomatic patients, 16% had late complications, while in asymptomatic patients, only 4%. Late complications were observed in the laparotomy group in seven patients (17%). We did not observe late complications in the laparoscopy group. Early surgical intervention is not followed by a high risk of complications and may prevent the onset of preoperative complications, giving excellent early and long-term results, especially after minimally invasive laparoscopic surgery. Full article
(This article belongs to the Special Issue Recent Advances in Hepatobiliary and Pancreatic Surgery in Children)
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15 pages, 894 KiB  
Article
The Impact of Hepatic Artery Thrombosis on the Outcome of Pediatric Living Donor Liver Transplantations
by Marek Stefanowicz, Piotr Kaliciński, Grzegorz Kowalewski, Adam Kowalski, Mateusz Ciopiński, Marek Szymczak, Agnieszka Kwiecińska, Waldemar Patkowski, Krzysztof Zieniewicz, Ireneusz Grzelak, Diana Kamińska and Hor Ismail
Children 2023, 10(2), 340; https://doi.org/10.3390/children10020340 - 9 Feb 2023
Cited by 2 | Viewed by 1482
Abstract
The aim of our study was to assess risk factors for hepatic artery thrombosis (HAT) and to evaluate the impact of HAT management on long-term outcomes after pediatric living donor liver transplantation (LDLT). We retrospectively analyzed 400 patients who underwent primary LDLT between [...] Read more.
The aim of our study was to assess risk factors for hepatic artery thrombosis (HAT) and to evaluate the impact of HAT management on long-term outcomes after pediatric living donor liver transplantation (LDLT). We retrospectively analyzed 400 patients who underwent primary LDLT between 1999 and 2020. We compared preoperative data, surgical factors, complications, and patient and graft survivals in patients with HAT (HAT Group) and without HAT (non-HAT Group). A total of 27 patients (6.75%) developed HAT. Acute liver failure, a hepatic artery (HA) anastomosis diameter below 2 mm, and intraoperative HA flow dysfunction were significantly more common in the HAT Group (p < 0.05, p = 0.02026, and p = 0.0019, respectively). In the HAT Group, 21 patients (77.8%) underwent urgent surgical revision. The incidence of biliary stenosis and retransplantation was significantly higher in the HAT Group (p = 0.00002 and p < 0.0001, respectively). Patient and graft survivals were significantly worse in the HAT Group (p < 0.05). The close monitoring of HA flow with Doppler ultrasound during the critical period of 2 to 3 weeks after LDLT and the immediate attempt of surgical revascularization may attenuate the elevated risk of biliary stenosis, graft loss, and the need for retransplantation due to HAT. Full article
(This article belongs to the Special Issue Recent Advances in Hepatobiliary and Pancreatic Surgery in Children)
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Review

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12 pages, 628 KiB  
Review
Management of Blunt Pancreatic Trauma in Children: A Persistent Controversy—Case Report and Comprehensive Literature Review
by Igor Sukhotnik and Neta Cohen
Children 2024, 11(1), 135; https://doi.org/10.3390/children11010135 - 22 Jan 2024
Viewed by 1226
Abstract
Blunt pancreatic injury (BPI) is relatively uncommon in children, and is associated with relatively high morbidity and mortality, especially if diagnosis is delayed. The aim of this report is to review the literature regarding controversial questions in the early diagnosis and management of [...] Read more.
Blunt pancreatic injury (BPI) is relatively uncommon in children, and is associated with relatively high morbidity and mortality, especially if diagnosis is delayed. The aim of this report is to review the literature regarding controversial questions in the early diagnosis and management of pediatric BPI. A representative case of blunt pancreatic trauma in a six-year-old girl with delayed diagnosis and intraoperative and postoperative complications was described. A systematic search of databases and the grey literature in Scopus and Web of Science using relevant keywords was conducted. A total of 26 relevant articles published in last 5 years were found in PubMed. Although early CT performance is considered part of initial pancreatic trauma workup, the sensitivity of CT for detecting main pancreatic duct injuries in children is relatively low. MRCP and ERCP (if available) are useful for assessing ductal injury and should be performed when the status of the pancreatic duct is unclear on the CT. Most patients with low-grade pancreatic damage may be treated conservatively. Although surgery involving distal pancreatectomy remains the preferred approach for most children with high-grade pancreatic injury, there is growing evidence to suggest that non-operative management (NOM) is safe and effective. Most pancreatic pseudo cysts following NOM had relatively mild complications, and most resolved spontaneously. For those children who do require surgery, a conservative operative approach with the least risk is advocated. In conclusion, the optimal management for pediatric pancreatic trauma is controversial. Further clinical trials are required to generate clinical practice guidelines on pancreatic trauma in a child population. Full article
(This article belongs to the Special Issue Recent Advances in Hepatobiliary and Pancreatic Surgery in Children)
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Other

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7 pages, 4608 KiB  
Case Report
Pediatric Pancreatic Endocrine Tumor Presenting as Acute Pancreatitis: A Case Report
by Shigetaka Fukuda, Mitsuyoshi Suzuki, Kei Minowa, Hiroyuki Koga, Atsuyuki Yamataka and Toshiaki Shimizu
Children 2023, 10(5), 900; https://doi.org/10.3390/children10050900 - 19 May 2023
Cited by 2 | Viewed by 1294
Abstract
Pancreatic neuroendocrine tumors (PNETs) are relatively rare, especially in the pediatric age group. This report describes a pediatric case of acute pancreatitis secondary to stenosis of the main pancreatic duct due to a PNET. The patient was a boy, thirteen and a half [...] Read more.
Pancreatic neuroendocrine tumors (PNETs) are relatively rare, especially in the pediatric age group. This report describes a pediatric case of acute pancreatitis secondary to stenosis of the main pancreatic duct due to a PNET. The patient was a boy, thirteen and a half years old, who presented with persistent low-grade fever, nausea, and abdominal pain. He was diagnosed with acute pancreatitis based on the elevation of serum pancreatic enzyme levels and abdominal ultrasonography findings of enlargement of the pancreas and dilatation of the main pancreatic duct. Abdominal contrast-enhanced computed tomography (CT) showed a 5.5 mm, contrast-enhanced mass in the head of the pancreas. His symptoms resolved with conservative treatment, although the pancreatic tumor grew slowly. At fifteen years and four months, since the tumor had enlarged to 8.0 mm, the patient underwent pancreaticoduodenectomy for therapeutic and diagnostic purposes. Based on the pathological evaluation, he was diagnosed with PNET (grade: G1). The patient has been free of tumor recurrence for 10 years and requires no additional therapy. In this report, the clinical characteristics of PNETs are also discussed, comparing the clinical features of adult-onset and pediatric-onset cases that initially present as acute pancreatitis. Full article
(This article belongs to the Special Issue Recent Advances in Hepatobiliary and Pancreatic Surgery in Children)
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