Green Approach in Synthesis of Bio-Inspired Materials (Second Edition)

A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".

Deadline for manuscript submissions: 5 April 2025 | Viewed by 2186

Special Issue Editors


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Guest Editor
Laboratory for Precipitation Processes, Ruđer Bošković Institute, Bijenička c. 54, 10000 Zagreb, Croatia
Interests: crystallization of sparingly soluble inorganic salts; crystal growth from aqueous solutions; mechanisms and precipitation kinetics; biomineralization; environmental protection; industrial crystallization
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Institute for General, Inorganic and Physical Chemistry and Teaching Methods in Chemistry, Department of Chemistry, Josip Juraj Strossmayer University of Osijek, Ulica cara Hadrijana 8/A, 31000 Osijek, Croatia
Interests: spontaneous precipitation; precipitation in vitro; precipitation with additives; pathological biomineralization; biomineralization
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Guest Editor
Department of Chemistry, University of Osijek, Cara Hadrijana 8A, 31000 Osijek, Croatia
Interests: electrochemistry; voltammetry; electrochemical impedance spectroscopy; antioxidants; macrocycclic chemistry; metal complexes; modified electrodes
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Guest Editor
Ruđer Bošković Institute, Bijenička c. 54, 10000 Zagreb, Croatia
Interests: biomineralization; basic research on the mechanisms and kinetics of the process of precipitation (nucleation, crystal growth) in solid-liquid systems; bioinspired crystallization
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Special Issue Information

Dear Colleagues,

Topics of interest for this Special Issue include studies on biomineralization/pathological biomineralization and the synthesis of bioinspired materials.

Biomineralization refers to the processes by which organisms deposit a mineral phase, which is usually indicated as biomineral, under mild chemical conditions, in an aqueous medium and at ambient temperatures. These processes can occur in both normal (e.g., the bone, tooth enamel, or shell of the mollusk) and pathological circumstances (ectopic mineral deposits). It is known that organisms have considerable control over the formation of biominerals and that the resulting organic–inorganic hybrid materials (biominerals) have remarkable physical–chemical or mechanical properties. Therefore, scientists strive to imitate biomineralization processes in order to synthesize new, bioinspired materials whose structure, properties, or function mimic those of naturally occurring materials. It is clear that the design of materials and structures inspired by nature represents a special challenge and that a multidisciplinary approach is needed. Additionally, the growing interest of researchers in biologically active compounds is encouraging the development of new bioinspired syntheses.

The goal of this Special Issue is also to promote the current trend of “green chemistry”. Green synthesis depends on the simplicity, cost effectiveness, and ecofriendliness for the production of well-characterized bioinspired materials. The validity of the synthesis depends on the nature of the solvent with minimal wastage in terms of energy and raw materials, safety in material synthesis, and reducing the impact on the environment.

We are delighted to invite researchers to participate in this Special Issue, entitled “Green Approach in Synthesis of Bioinspired Materials". Papers related to the green approach on the following topics, as well as to the keywords listed below, are welcomed:

  • The synthesis and characterization of biominerals as well as the investigation of biomineralization/pathological biomineralization mechanisms;
  • Bio-inspired synthesis of materials;
  • The assembly and applications of bioinspired materials as well as crystallization pathway studies.

Dr. Jasminka Kontrec
Dr. Anamarija Stanković
Dr. Martina Medvidović-Kosanović
Dr. Branka Njegić Džakula
Guest Editors

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Keywords

  • biomineralization
  • pathological biomineralization
  • green synthesis
  • bioinspired synthesis
  • biologically active compounds
  • additives
  • antioxidants

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Published Papers (2 papers)

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Research

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19 pages, 9184 KiB  
Article
Investigating the Role of CNP and CNP Aggregates in the Rheological Breakdown of Triglyceride Systems
by Ivana A. Penagos, Fien De Witte, Tom Rimaux, Koen Dewettinck and Filip Van Bockstaele
Crystals 2024, 14(6), 566; https://doi.org/10.3390/cryst14060566 - 19 Jun 2024
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Abstract
In many food applications, the mechanical properties of fats play a critical role in determining the processing performance of fat-rich products. In fact, fat crystal networks form a particular class of soft materials that exhibit viscoelastic properties. The uniqueness of the mechanical response [...] Read more.
In many food applications, the mechanical properties of fats play a critical role in determining the processing performance of fat-rich products. In fact, fat crystal networks form a particular class of soft materials that exhibit viscoelastic properties. The uniqueness of the mechanical response is intricately linked to the hierarchical nature of the system, as fats possess a complex architecture encompassing features at different scale levels (i.e., length scales). Since the discovery of crystalline nanoplatelets (CNPs), it has been hypothesized that CNPs are the basic building blocks of lipid networks and that CNPs are the responsible units for the mechanical properties of fats. This hypothesis, however, has only been partially tested. In this article, we examine which units could be responsible (e.g., lamellae, CNP, CNP aggregates) for the mechanical breakdown of fat crystal networks, through Rheo-USAXS in beamline ID02 (ESRF, Grenoble, France). Time-resolved USAXS profiles were acquired during the three steps of a three-interval thixotropy test (3iTT), namely, pre-shear, shear and recovery. The results were then utilized to evidence which specific length scale is arranged (i.e., orientated) during rheological breakdown. The findings suggest that, at the tested shear rates, orientation is only visible from 250 nm onwards, suggesting that the rheological breakdown of triglycerides is primarily driven by the orientation, and possible disruption, of CNP aggregates. These results reveal the critical role of CNP aggregates in the mechanical properties of fats. In the longer term, we believe this study will steer future research toward a more focused understanding of CNP aggregation and disaggregation dynamics. Full article
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18 pages, 5701 KiB  
Review
Advancements in the Engineering Modification of Sucrose Phosphorylase
by Shuru Ma, Hongyu Zhang, Tingting Lou and Suying Wang
Crystals 2024, 14(11), 972; https://doi.org/10.3390/cryst14110972 - 9 Nov 2024
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Abstract
Sucrose phosphorylase (SPase) is a member of the glycoside hydrolase family 13, catalyzing the reversible phosphorolysis of sucrose to produce α–glucose–1–phosphate and exhibiting transglycosylation activity toward multiple substrates. Its wide substrate specificity enables the synthesis of various glycosides, which are broadly applied in [...] Read more.
Sucrose phosphorylase (SPase) is a member of the glycoside hydrolase family 13, catalyzing the reversible phosphorolysis of sucrose to produce α–glucose–1–phosphate and exhibiting transglycosylation activity toward multiple substrates. Its wide substrate specificity enables the synthesis of various glycosides, which are broadly applied in food, cosmetics, and pharmaceuticals. However, the industrial application of SPase is constrained by its poor thermostability and limited transglycosylation activity. Therefore, current research focuses on enhancing the thermostability and transglycosylation activity of SPase through efficient engineering strategies based on its crystal structure and catalytic mechanism. This paper systematically reviews the crystal structure and catalytic mechanism of SPase, outlines the application of protein engineering and immobilization strategies in improving the thermostability of SPase, and analyzes how modifications at key amino acid sites affect the synthesis of typical glycosylation products. It also summarizes the limitations of SPase engineering modification strategies and explores the potential of diversified approaches for SPase modification, highlighting its broad application prospects in industrial production and laying a solid foundation for further advancements in SPase engineering modification and its industrial application. Full article
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