Novel Therapeutics and Prognostications in Gastrointestinal Cancer
A special issue of Gastroenterology Insights (ISSN 2036-7422). This special issue belongs to the section "Gastrointestinal Disease".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 8755
Special Issue Editor
Interests: urothelial cancer; sarcoma; molecular pathology; experimental therapeutics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Gastrointestinal (GI) cancer is one of the most common cancers worldwide and leads to a number of cancer-related cases of morbidity and mortality. GI cancer is heterogeneous, involving a wide range of organs including the esophagus, stomach, hepatobiliary system, pancreas, small and large intestines, rectum, and anus. It is also quite diverse as regards its histological types, which consist mainly of adenocarcinoma, followed by neuroendocrine tumor, sarcoma, and hematopoietic neoplasms. The etiology is also quite diverse. For example, gastroesophageal reflux disease, Helicobacter pylori, inflammatory bowel disease, and hepatitis B or C virus infection are associated with the development of esophageal, gastric, intestinal, and liver cancers, respectively. Of note, a certain number of GI cancers can be inherited. It is also worth noting that GI cancer is often diagnosed in an advanced stage. For those, traditional chemotherapy may benefit patient outcome, but survival remains poor. Recently, various targeted therapies have been developed based on an increased understanding of the molecular features and immunogenicity of GI cancers, and remarkable survival benefits in certain subsets of patients have been archived. Accordingly, systemic identification and validation of novel therapeutics and prognostic models and biomarkers would most likely be beneficial for patients.
With this concept, the aim of this Special Issue is to collect manuscripts associated with the following points to allow the delivery of precision oncology in GI cancers:
- Prognostic patterns/models (either statistics or biomedical) for GI cancers;
- Novel biomarkers carrying either therapeutic or prognostic values for GI cancers;
- Novel agents or novel strategies for the treatment of GI cancers, either in vitro or in vivo.
Prof. Dr. Chien-Feng Li
Guest Editor
Manuscript Submission Information
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Keywords
- gastrointestinal cancers
- molecular
- pathogenesis
- prognosis
- therapy
- theragnostic
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