Application of Hydrogels in 3D Bioprinting for Tissue Engineering

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".

Deadline for manuscript submissions: 20 June 2025 | Viewed by 710

Special Issue Editors


E-Mail Website
Guest Editor
Department of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, 27201 Kladno, Czech Republic
Interests: stem cells; bioprinting; gels; biomedical materials

E-Mail Website
Guest Editor
Department of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, 27201 Kladno, Czech Republic
Interests: decellularization; bioreactors; bioprinting; gels

Special Issue Information

Dear Colleagues,

Bioprinting is a promising method in the field of tissue engineering, which is used to create three-dimensional structures of living tissues and organs using a combination of cells, biomaterials, and printing techniques. Bioprinting has several applications in the field of medicine, including the creation of tissues and organs for transplantation, drug development and testing, and disease modeling and research. Creating tissues and organs that closely resemble natural ones could help address the shortage of donor organs and reduce the risk of transplant rejection. Bioprinting can also enable the development of new drugs and therapies by allowing researchers to test them on tissue models that accurately mimic the human body. Additionally, bioprinted tissues can be used to study and understand various diseases, leading to new insights and treatments.

Bioprinting uses a variety of materials, including living cells, biomaterials, and supporting structures. The living cells can be derived directly from the patient's own body or a donor, and they are combined with biomaterials such as hydrogels, polymers, and extracellular matrix components. These materials provide a support structure for the cells and can help to guide their growth and development into the desired tissue or organ. The supporting structures used in bioprinting can be made from a range of materials, including synthetic polymers, ceramics, and metals. The choice of materials used in bioprinting depends on the specific application and the desired properties of the final product.

This Special Issue focuses on the use of bioprinting for tissue engineering purposes. This includes both the actual preparation and characterization of hydrogels and bioinks, as well as the actual methods of bioprinting, including extrusion printing, inkjet printing, laser or light processing printing, and finally the application of printed structures for tissue engineering.

Dr. Jana Matejkova
Dr. Roman Matejka
Guest Editors

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Keywords

  • bioprinting
  • bioinks
  • hydrogels for bioprinting
  • gelling systems
  • bioprinting systems
  • injectable hydrogels
  • bioprinting properties
  • tissue scaffolds
  • tissue replacements
  • wound healing
  • gelling excipients

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Published Papers (1 paper)

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Review

29 pages, 2414 KiB  
Review
Current Status of Bioprinting Using Polymer Hydrogels for the Production of Vascular Grafts
by Jana Matějková, Denisa Kaňoková and Roman Matějka
Gels 2025, 11(1), 4; https://doi.org/10.3390/gels11010004 - 26 Dec 2024
Viewed by 428
Abstract
Cardiovascular disease is one of the leading causes of death and serious illness in Europe and worldwide. Conventional treatment—replacing the damaged blood vessel with an autologous graft—is not always affordable for the patient, so alternative approaches are being sought. One such approach is [...] Read more.
Cardiovascular disease is one of the leading causes of death and serious illness in Europe and worldwide. Conventional treatment—replacing the damaged blood vessel with an autologous graft—is not always affordable for the patient, so alternative approaches are being sought. One such approach is patient-specific tissue bioprinting, which allows for precise distribution of cells, material, and biochemical signals. With further developmental support, a functional replacement tissue or vessel can be created. This review provides an overview of the current state of bioprinting for vascular graft manufacturing and summarizes the hydrogels used as bioinks, the material of carriers, and the current methods of fabrication used, especially for vessels smaller than 6 mm, which are the most challenging for cardiovascular replacements. The fabrication methods are divided into several sections—self-supporting grafts based on simple 3D bioprinting and bioprinting of bioinks on scaffolds made of decellularized or nanofibrous material. Full article
(This article belongs to the Special Issue Application of Hydrogels in 3D Bioprinting for Tissue Engineering)
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