Epigenetics in Human Development and Diseases
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 25 March 2025 | Viewed by 1081
Special Issue Editors
Interests: epigenetic; DNA methylation; oral diseases; multifactorial diseases; genetic
Special Issues, Collections and Topics in MDPI journals
Interests: genetic; epigenetic; human development and diseases; oral diseases; molecular biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The molecular era has unraveled aspects of epigenetics in development and disease in humans. The great advancements in this area mainly come from data referring to tumor diseases; however, epigenetic aspects of human development and in inflammatory and mental diseases are still neglected in this regard. Epigenetic markers (DNA methylation, RNA methylation, histone modification, and micro-RNAs) can be used as biomarkers and, since they are reversible, they can also be targets for treatments. In addition to genetic studies, the epigenetic approach can contribute to precision medicine, a healthcare model which advocates for the construction of biological databases for each individual based on concepts of classical genetics, epigenetic marks, metabolomics, and aspects of the patient's clinical phenotype, enabling the establishment of more accurate lines of diagnosis and treatment. This is a promising perspective that could be applied for reducing healthcare costs and lessening patient suffering.
The types of manuscripts we are interested in include original research, reviews, mini reviews, and case reports.
Specific themes include:
- DNA methylation and RNA methylation marks which are involved in human development and disease;
- Histone modification marks including methylation, acetylation, etc., which are involved in human development and disease;
- Non-coding RNA expression, including miRNA, lncRNA, etc., which are involved in human development and disease;
- Studies with epigenetic drugs will also be considered.
Dr. Naila Francis Paulo De Oliveira
Dr. Maria Cristina Leme Godoy dos Santos
Guest Editors
Manuscript Submission Information
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Keywords
- health development
- inflammatory diseases
- mental diseases
- tumor diseases
- epigenetic drugs
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