Genetic Code Origin
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (25 September 2023) | Viewed by 4236
Special Issue Editor
Special Issue Information
Dear Colleagues,
The genetic code is the set of rules used by living cells to translate information encoded within genetic material (DNA or mRNA sequences of nucleotide triplets, or codons) into proteins. Crick, Brenner, Barnett, and Watts-Tobin first demonstrated that codons consist of three DNA bases. Marshall Nirenberg and Heinrich J. Matthaei were the first to reveal the nature of a codon in 1961.
There are two general thoughts on the researches of genetic code origin. The first put the physicochemical properties of amino acids as the core of genetic code origin. The second line of thought maintains that the metabolic and biosynthetic relationships between amino acids are the main force in defining the evolutionary organization of the genetic code, and that the properties of amino acids play only a secondary role in this organization. This Special Issue, entitled “Genetic Code Origin”, aims to provide a comprehensive overview of the most recent advances in this timely topic and a preview to future research directions and challenges.
Dr. Massimo Di Giulio
Guest Editor
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Keywords
- genetic code
- codon
- tRNA
- evolution
- amino acid
- physicochemical properties of amino acids
- origin of life
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