Genetics and Genomics of Leishmania
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Microbial Genetics and Genomics".
Deadline for manuscript submissions: closed (20 September 2022) | Viewed by 10937
Special Issue Editors
Interests: genomics; transcriptomics; proteomics; Leishmania; omics; massive data analysis
Interests: Leishmania; gene expression; genomics; transcriptomics; proteomics; heat shock proteins; RNA binding proteins; phylogenetics; trypanosomatids
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Parasites of the genus Leishmania are well-known as causative agents of leishmaniasis, a group of diseases affecting millions of persons living in tropical and subtropical regions. There is currently no acceptable vaccine for humans, and treatment options are limited (low number of drugs and with high toxicity). Efforts are needed to find better low toxicity drugs and to elucidate resistance mechanisms that preclude efficiency of current available ones. In addition, our understanding of the Leishmania virulence factors responsible for these diseases is limited. Integrated research into the molecular biology of these pathogens is needed to establish how these parasites infect, replicate, and are transmitted to new hosts.
In the past fifteen years, great progress has been made in our understanding of Leishmania. The advent of high-throughput technologies has led to the accumulation of a massive amount of genomic data. Now, it is time to integrate this information, together with studies dealing with transcriptomics and proteomics analyses, to decipher particularities in the molecular mechanisms and biosynthetic pathways of this parasite. This knowledge will contribute to designing new strategies to combat these devastating diseases.
This Special Issue welcomes original research articles dealing with topics around the genetics, genomics, transcriptomics, and proteomics of Leishmania parasites. Studies focusing on pathogen–host interactions, traits of drug resistance, phylogenetics, and evolution of these organisms are also within the scope of this Special Issue. Additionally, review articles are welcome which cover the current literature and present a synthesis of our current knowledge of these pathogens and the genetic processes that make them successful.
Dr. Begoña Aguado
Dr. Jose M. Requena
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Gene expression mechanisms and methods
- Genomics
- Transcriptomics studies
- Proteomics analysis
- Drugs resistance mechanisms
- Species-specific genes
- Metabolic enzymes
- Phylogenetic and phylogenomic analyses
- Evolution
- Leishmania-related organisms
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.