Assessment of Normal and Abnormal Functions of the Human Embryonic and Fetal Cardiovascular System: In Vivo and In Vitro Studies
A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Cardiac Development and Regeneration".
Deadline for manuscript submissions: closed (30 November 2022)
Special Issue Editor
Interests: cardiovascular development; cardiac looping; visceral left-right asymmetry; biomechanics; pumping mechanism of valveless heart tubes; form–function relationships; in vivo imaging; proepicardial development; congenital heart defects
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The Journal of Cardiovascular Development and Disease (JCDD) has launched a Special Issue on the assessment of normal and abnormal functions of the human embryonic and fetal cardiovascular system. Studies on animal embryos and fetuses have shown that functional factors (fluid flow, pressure, shear forces, etc.) play important roles in the normal prenatal morphogenesis of the cardiovascular system as well as in the prenatal morphogenesis and progression of congenital cardiovascular diseases. Understanding the normal and abnormal development of the prenatal function of our cardiovascular system, therefore, may improve prenatal diagnosis and therapy for congenital cardiovascular diseases.
For a long time period, our knowledge about the functional development of the human embryonic and fetal cardiovascular system was derived almost exclusively from the extrapolation of observations of animal embryos/fetuses to the human species. Very few data came from studies on human embryos or fetuses that had survived abortion for a short time. The development of non-invasive imaging techniques, such as Doppler–ultrasonography or fetal cardiovascular magnetic resonance imaging, has made it possible to assess the function of the human embryonic and/or fetal cardiovascular system in utero. Therefore, our knowledge about the prenatal function of the human cardiovascular system nowadays does not reply exclusively on observations made for animals.
The Special Issue aims to stimulate the exchange of knowledge about the prenatal function of the cardiovascular system between those who study these function in animal embryos/fetuses and those who study them in human embryos/fetuses. Research papers and review articles on any aspect related to the abovementioned topics are weclome. This Special Issue will provide a platform for the presentation and discussion of our current knowledge on the prenatal development of the human cardiovascular system and its functions
Prof. Dr. Jörg Männer
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- human embryo
- human fetus
- embryonic cardiovascular function
- fetal cardiovascular function
- congenital cardiovascular diseases
- prenatal imaging
- prenatal cardiovascular physiology
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