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Feature Papers in Biomaterials for Drug Delivery
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Feature Papers in Biomaterials for Drug Delivery

A topical collection in Journal of Functional Biomaterials (ISSN 2079-4983). This collection belongs to the section "Biomaterials for Drug Delivery".

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Editor

Dr. Junjie Li

E-Mail Website
Collection Editor
Institute for Materials Chemistry and Engineering (IMCE), Kyushu University, Fukuoka, Japan
Interests: polymer and self-assembly; polymersomes; nanomedicine; biomaterials; biocompatible coatings
Special Issues, Collections and Topics in MDPI journals

Topical Collection Information

Dear Colleagues,

This Topical Collection, entitled “Feature Papers in Biomaterials for Drug Delivery”, of the Journal of Functional Biomaterials is set to comprise important contributions from scholars and Editorial Board Members. This collection will feature high-quality research papers and review articles that highlight some of the innovative and impactful research in the field of biomaterials for drug delivery.

The collection will showcase cutting-edge approaches across a broad spectrum of biomaterials, including nanoparticles, hydrogels, microneedles, implantable devices, and cell-inspired/-based therapeutics. The papers will explore the latest strategies for targeted drug delivery, controlled release, and enhanced therapeutic efficacy. Additionally, they will address key challenges such as overcoming biological barriers, minimizing side effects, and improving patient adherence to treatment regimens.

Whether you are a researcher, clinician, or student, this collection will provide a comprehensive overview of the state of the art in this rapidly evolving field. By bringing together leading experts from around the world, these feature papers will offer a wealth of information on the latest trends and breakthroughs at the intersection of materials science and medicine.

Dr. Junjie Li
Collection Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • nanomaterials
  • drug delivery
  • controlled release
  • targeted delivery

Published Papers (2 papers)

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2025

Jump to: 2024

17 pages, 2019 KiB  
Review
From Blood to Therapy: The Revolutionary Application of Platelets in Cancer-Targeted Drug Delivery
by Lijuan Xie, Fengxu Gan, Yun Hu, Yibin Zheng, Junshan Lan, Yuting Liu, Xiaofang Zhou, Jianyu Zheng, Xing Zhou and Jie Lou
J. Funct. Biomater. 2025, 16(1), 15; https://doi.org/10.3390/jfb16010015 - 6 Jan 2025
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Abstract
Biomimetic nanodrug delivery systems based on cell membranes have emerged as a promising approach for targeted cancer therapy due to their biocompatibility and low immunogenicity. Among them, platelet-mediated systems are particularly noteworthy for their innate tumor-homing and cancer cell interaction capabilities. These systems [...] Read more.
Biomimetic nanodrug delivery systems based on cell membranes have emerged as a promising approach for targeted cancer therapy due to their biocompatibility and low immunogenicity. Among them, platelet-mediated systems are particularly noteworthy for their innate tumor-homing and cancer cell interaction capabilities. These systems utilize nanoparticles shielded and directed by platelet membrane coatings for efficient drug delivery. This review highlights the role of platelets in cancer therapy, summarizes the advancements in platelet-based drug delivery systems, and discusses their integration with other cancer treatments. Additionally, it addresses the limitations and challenges of platelet-mediated drug delivery, offering insights into future developments in this innovative field. Full article
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2024

Jump to: 2025

25 pages, 1462 KiB  
Review
Targeting Reactive Oxygen Species for Diagnosis of Various Diseases
by Moung Young Lee, Donguk Lee, Dayun Choi, Kye S. Kim and Peter M. Kang
J. Funct. Biomater. 2024, 15(12), 378; https://doi.org/10.3390/jfb15120378 - 15 Dec 2024
Viewed by 1125
Abstract
Reactive oxygen species (ROS) are generated predominantly during cellular respiration and play a significant role in signaling within the cell and between cells. However, excessive accumulation of ROS can lead to cellular dysfunction, disease progression, and apoptosis that can lead to organ dysfunction. [...] Read more.
Reactive oxygen species (ROS) are generated predominantly during cellular respiration and play a significant role in signaling within the cell and between cells. However, excessive accumulation of ROS can lead to cellular dysfunction, disease progression, and apoptosis that can lead to organ dysfunction. To overcome the short half-life of ROS and the relatively small amount produced, various imaging methods have been developed, using both endogenous and exogenous means to monitor ROS in disease settings. In this review, we discuss the molecular mechanisms underlying ROS production and explore the methods and materials that could be used to detect ROS overproduction, including iron-based materials, ROS-responsive chemical bond containing polymers, and ROS-responsive molecule containing biomaterials. We also discuss various imaging and imaging techniques that could be used to target and detect ROS overproduction. We discuss the ROS imaging potentials of established clinical imaging methods, such as magnetic resonance imaging (MRI), sonographic imaging, and fluorescence imaging. ROS imaging potentials of other imaging methods, such as photoacoustic imaging (PAI) and Raman imaging (RI) that are currently in preclinical stage are also discussed. Finally, this paper focuses on various diseases that are associated with ROS overproduction, and the current and the future clinical applications of ROS-targeted imaging. While the most widely used clinical condition is cardiovascular diseases, its potential extends into non-cardiovascular clinical conditions, such as neurovascular, neurodegenerative, and other ROS-associated conditions, such as cancers, skin aging, acute kidney injury, and inflammatory arthritis. Full article
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