In Honor of Prof. Dr. Osvaldo Cascone: From His Biotechnology Lessons to Industrial Application

Special Issue Editors


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Guest Editor
Cátedra de Biotecnología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires (UBA), Inst. NANOBIOTEC UBA-CONICET, Junín 956, Buenos Aires 1113, Argentina
Interests: protein purification; immunogenic peptides; vaccines; antivenoms; bioactive peptides; immunoassays

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Guest Editor
Cátedra de Biotecnología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires (UBA), Inst. NANOBIOTEC UBA-CONICET, Junín 956, Buenos Aires 1113, Argentina
Interests: protein expression and purification; baculovirus-larvae platform; antivenom; veterinary vaccines; immunoassays

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Guest Editor
Cátedra de Biotecnología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires (UBA), Inst. NANOBIOTEC UBA-CONICET, Junín 956, Buenos Aires 1113, Argentina
Interests: protein purification; adsorptive technology; chromatography; biopolymers

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Guest Editor
1. School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa
2. Department of Organic Chemistry, University of Barcelona, Barcelona, Spain
Interests: antimicrobial peptides; solid-phase chemistry; combinatorial chemistry; drug delivery systems; peptide drug conjugates; orthogonal chemistry; drug discovery; biomaterials
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Special Issue Information

Dear Colleagues,

We are announcing this Special Issue in honor of Prof. Dr. Osvaldo Cascone (1943-2024), whose distinguished career in the fields of biochemistry and biotechnology deserves recognition and celebration. The aim of this Special Issue is to collate papers (articles, short communications, reviews, perspectives, opinions) focused on the biotechnology process.

Professor Cascone graduated with honors in Biochemistry and Pharmacy from the Faculty of Pharmacy and Biochemistry (FF&B) at the University of Buenos Aires (UBA). He received his PhD in Pharmacy and Biochemistry from the same institution and took position as a Researcher at the National Scientific and Technical Research Council (CONICET); during his career, he was promoted to Senior Researcher and Associate and Consultant Professor, and then to Biotechnology Chair, at FF&B, UBA.

He developed great expertise in protein purification at the industrial scale during his stays in Sanofi-ELF Biorecherches (Toulouse, France), the University of Reading (United Kingdom), and Pharmacia (Uppsala, Sweden), and he led high-impact research projects and mentored the next generation of students, scientists, and professionals. He made exceptional pioneering contributions to biotechnology, especially in terms of large-scale protein expression and purification. "Do not purify more than necessary” he always said to his undergraduate and PhD students, with the aim and great desire to reduce the cost of the process and increase its yields. He successfully directed projects supported by major national and international institutions and created many research groups dedicated to optimizing the biotechnology process from upstream to downstream. Such highly fruitful research resulted in over 160 articles being published in prestigious scientific journals and book chapters with renowned publishers, as well as in the supervision of numerous doctoral and master's theses. His love for teaching has been reflected in his immense contributions throughout his prolific academic career, during which he designed and directed many signatures in the field of biotechnology and over 65 postgraduate courses, especially in protein purification.

Because of his great contributions, Professor Cascone was honored with the "Faculty of Pharmacy and Biochemistry" award for academic excellence and the "Bernardo Houssay" award for research excellence, among others.

His dedication and contributions have left a significant mark on the scientific community, and his work deserves to be recognized through this Special Issue in his honor.

Dr. Silvia Andrea Camperi
Prof. Dr. María Victoria Miranda
Dr. Federico Wolman
Prof. Dr. Fernando Albericio
Guest Editors

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Keywords

  • biotechnology process and scaling-up
  • biopharmaceuticals
  • vaccines
  • antivenoms
  • protein expression and purification
  • peptides
  • immunoassays

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Published Papers

This special issue is now open for submission.
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