Membrane Interactions in Biology

A special issue of Membranes (ISSN 2077-0375). This special issue belongs to the section "Biological Membrane Functions".

Deadline for manuscript submissions: closed (15 October 2021) | Viewed by 3867

Special Issue Editor


E-Mail Website
Guest Editor
Physical Chemistry and Soft Matter, Wageningen University and Research, Stippenweg 4, 6708 WE Wageningen, The Netherlands
Interests: membranes; cytoskeleton; liquid–liquid phase separation; synthetic biology; microfluidics; self-oganization

Special Issue Information

Dear Colleagues,

Life, as we know it, does not exist without membranes. Living cells are enveloped within lipid bilayers, safeguarding and allowing the self-organization of the inner biomolecular soup. These self-assembled membranous boundaries distinguish and, in a way, define cells and further allow controlled communication with the surroundings. Membranes are thus undoubtedly one of the most important biological interfaces.

We have known for a long time that membranes are anything but inert. The complex cellular interior as well as the external environment continuously interacts with the cell membrane. From understanding membranes as a fascinating biomaterial, we are now in an era of understanding the complex interplay of membranes with other important classes of biomolecules. Numerous in vivo and in vitro studies are revealing the dynamic interactions of membranes with other components, such as cytoskeleton, genomes, and, in recent years, phase-separated biomolecular condensates. These findings are not only crucial to understanding cell biology in further detail, but also foundational for designing biomimetic artificial entities. Furthermore, novel on-chip microfluidic assays are proving to be crucial to achieving more complex and controlled experimentation and are an integral part of further scientific progress.

This Special Issue, “Membrane Interactions in Biology”, aims to cover the latest developments on interactions of biomolecules with natural/cell-mimicking membranes. We welcome original research papers as well as review articles related to any aspect of membrane–biomolecule interactions and associated technological advancements.

Dr. Siddharth Deshpande
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Membranes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Membrane dynamics
  • Membrane–protein interactions
  • Membrane–cytoskeleton interactions
  • Membrane–chromosome interactions
  • Membrane–biomolecular condensate interactions
  • Membrane-bound liquid–liquid phase separation
  • Liposome morphogenesis
  • Synthetic biology
  • Synthetic cells
  • On-chip microfluidic assays

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

19 pages, 3396 KiB  
Review
Synthetic Cell as a Platform for Understanding Membrane-Membrane Interactions
by Bineet Sharma, Hossein Moghimianavval, Sung-Won Hwang and Allen P. Liu
Membranes 2021, 11(12), 912; https://doi.org/10.3390/membranes11120912 - 23 Nov 2021
Cited by 10 | Viewed by 3224
Abstract
In the pursuit of understanding life, model membranes made of phospholipids were envisaged decades ago as a platform for the bottom-up study of biological processes. Micron-sized lipid vesicles have gained great acceptance as their bilayer membrane resembles the natural cell membrane. Important biological [...] Read more.
In the pursuit of understanding life, model membranes made of phospholipids were envisaged decades ago as a platform for the bottom-up study of biological processes. Micron-sized lipid vesicles have gained great acceptance as their bilayer membrane resembles the natural cell membrane. Important biological events involving membranes, such as membrane protein insertion, membrane fusion, and intercellular communication, will be highlighted in this review with recent research updates. We will first review different lipid bilayer platforms used for incorporation of integral membrane proteins and challenges associated with their functional reconstitution. We next discuss different methods for reconstitution of membrane fusion and compare their fusion efficiency. Lastly, we will highlight the importance and challenges of intercellular communication between synthetic cells and synthetic cells-to-natural cells. We will summarize the review by highlighting the challenges and opportunities associated with studying membrane–membrane interactions and possible future research directions. Full article
(This article belongs to the Special Issue Membrane Interactions in Biology)
Show Figures

Figure 1

Back to TopTop