Anti-inflammatory Activities of Natural Products—Third Edition

Dear Colleagues,

Inflammation involves several steps to respond to harmful stimuli, such as pathogen agents, tissue lesions, and irritants, in order to destroy or isolate those agents, remove damaged tissues, and restore tissue homeostasis. The first step consists of the recognition of infection and damage, the second step consists of the activation of common signaling pathways, and the third step consists of the transcription and translation of genes, that is, the inducible expression of pro-inflammatory cytokines. These molecules, together with chemokines, originate the recruitment of monocytes and neutrophils to a damaged site, passing selectively through endothelial cells with a protein-rich fluid. Whereas acute inflammation involves an immediate and early response to an injurious agent and is quickly resolved, disturbance persists in chronic inflammation. Chronic inflammation is associated with a variety of cardiovascular, metabolic, and neurodegenerative diseases.

Plants, plant products, marine compounds, mushrooms, and bee products (honey, propolis, bee pollen) are examples of materials that have been the target of many studies in order to find effective anti-inflammatory compounds or extracts. Such studies include not only the isolation and identification of compounds but also the determination of the mechanisms involved in the anti-inflammatory activity.

This Special Issue, titled “Anti-inflammatory Activities of Natural Products—Third Edition”, invites researchers to contribute original research or review articles related to the anti-inflammatory activity, including mechanisms and pharmacological characterization, of extracts, fractions, or purified substances (extraction procedures, isolation, and identification) from mushrooms, bee products, marine sources, or plants. This Special Issue will not accept papers reporting only on the activity of extracts but lacking any chemical characterization of their components.

I look forward to receiving your contributions.

Dr. Maria da Graça Costa G. Miguel
Guest Editor

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• inflammation
• anti-inflammatory
• natural products
• pharmacology
• plant
• marine

• Anti-Inflammatory Activity of Natural Products II in Molecules (12 articles)