Biomaterials in Bone Regeneration
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 271
Special Issue Editors
Interests: molecular biology; cell cycle; stem cells; bone metabolism; regenerative medicine
Special Issue Information
Dear Colleagues,
The treatment of severe bone defects caused by fractures, cancers, congenital abnormalities, etc., remains a significant challenge. Reconstructive surgeries using autografts involve additional surgical stress and limit the amount of tissue that can be grafted. The efficiency of bone regeneration in allografts or xenografts is lower than in autografts.
To overcome these problems, bone regeneration therapy using osteogenic compounds or biomaterials has been eagerly studied. Osteogenic small molecules are utilized for local administration or osteogenic induction in cell-based therapy, and these molecules are also useful in terms of stability and safety compared with recombinant proteins. In addition, novel biomaterials efficiently induce bone formation and the new bones exhibit properties equivalent to the surrounding bone.
This Special Issue will focus on the novel in vivo or in vitro studies of osteogenic compounds and biomaterials for bone regeneration.
Dr. Toru Ogasawara
Dr. Fumiko Yano
Guest Editors
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Keywords
- biomaterials
- osteogenic compounds
- bone metabolism
- bone regeneration
- macromolecules
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