Antibacterial Drug Discovery: Chemical Challenges and Opportunities
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 207
Special Issue Editor
Interests: anti-cancer drugs; antibiotics; antibacterial agents; bacterial infections; drug-resistant pathogens; medicinal chemistry; natural products; rational drug design; repurposing existing drugs and drug targets
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The majority of antibacterial agents applied in the current clinical practices were introduced before the 1980s. Some bacteria have already acquired extensively drug resistance to these classic antibacterial agents; therefore, multidrug-resistant bacteria represent a major public health problem. Despite the increase in antimicrobial resistance, the development of new antimicrobial agents by large pharmaceutical industries is declining. The continuous development of new antibacterial agents is essential to combating the global threat of antibiotic resistance. In recent years, governments and non-profit organizations have played a critical role in supporting and stimulating the private and public sectors.
Antibacterial drug discovery employs innovative translational sciences, including target-oriented drug discovery, organic synthesis, drug delivery, and analytical and assay methods. The aim of this “Special Issue” is to highlight the challenges and opportunities presented by antibacterial drug discovery. This Special Issue may include original research articles and reviews on drug targets, medicinal chemistry, chemical entities, assays, phage therapy, vaccine, computational chemistry, new formulations, pharmacokinetic and dynamic aspects, and new strategies to using approved drugs.
Prof. Dr. Michio Kurosu
Guest Editor
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Keywords
- antibacterial agents
- antibacterial drug discovery
- medicinal chemistry
- pharmacology
- drug delivery
- structural chemistry
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