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Antioxidant Properties of Bioactive Compounds from Plants

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 21

Special Issue Editors


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Guest Editor
Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: synthesis and biological studies on anti-inflammatory and antioxidant agents, on inhibitors of enzymes implicated in the inflammation and in the coagulation process in general; correlation of inflammation with cancer; neurodegeneration; antioxidant activity; theoretical and experimental calculation of physicochemical parameters implicated in biological response; use of computational chemistry in drug design as well as bioactive compounds of natural origin, e.g., essential oils
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: drug design; anti-inflammatory; lipoxygenase inhibitors; cinnamic acids; coumarins

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Guest Editor Assistant
Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: phytochemistry; natural products; nutraceuticals; antioxidant activity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plant materials, such as vegetables, fruits, leaves, oilseeds, cereal crops, barks and roots, spices, and herbs, as well as crude plant drugs, are potential sources of antioxidant compounds like flavonoids, phenolic acids, stilbenes, tannins, lignans, and lignin, which are contained within leaves, flowering tissues, and woody parts such as stems and barks. All these compounds are known to neutralize free radicals, reduce oxidative stress, and support the body's own antioxidant defense system. Reactive oxygen species (ROS) and other free radicals can cause oxidative stress, leading to cellular damage and various chronic diseases like cancer, cardiovascular disease, and neurodegenerative disease. 

Research findings support that geographical location and season are factors that can influence the chemical composition of a plant. Also, different plants have different classes of chemical antioxidants as well as different amounts of antioxidant compounds.

Several in vitro protocols have been used to provide a comprehensive assessment of plant extracts, including the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay, the FRAP (ferric reducing antioxidant power) assay, the ORAC (oxygen radical absorbance capacity) assay, and the ABTS (2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) assay.

Several factors influence the antioxidant activity of a plant extract, such as the extraction procedure, the solvent, and plant-specific factors.

We look forward to your submissions.

Prof. Dr. Dimitra Hadjipavlou-Litina
Guest Editor

Dr. Ioannis Fotopoulos
Dr. Olga Tsiftsoglou
Guest Editor Assistants

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • reactive oxidant species
  • antioxidant protocols
  • antioxidant compounds
  • factors of influence
  • diseases

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This special issue is now open for submission.
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