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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Micro/Nanomaterials for Catalysis
edited by Juzhe Liu
submission deadline 31 Jan 2027 | Viewed by 74 | Submission Open
Keywords: micro/nanomaterials; catalysis; diverse applications; enhanced performance; advances
(This special issue belongs to the Section Materials Chemistry)
Phytochemistry, Biological Activities and Nanomaterial Applications of Medicinal and Aromatic Plants submission deadline 31 Jan 2027 | Viewed by 71 | Submission Open
Keywords: medicinal and aromatic plants; phytochemicals; bioactive natural products; biological activities; antioxidant and antimicrobial activity; green synthesis of nanoparticles; plant-mediated nanoparticles; metal and metal oxide nanoparticles; nanotechnology in biomedicine
(This special issue belongs to the Section Natural Products Chemistry)
New Insights into Maillard Reaction
edited by Junjian Miao and
submission deadline 31 Jan 2027 | Viewed by 52 | Submission Open
Keywords: Maillard reaction; advanced glycation end-products (AGEs); food chemistry; flavor formation; non-enzymatic browning; acrylamide mitigation; reaction kinetics; nutritional impact; bioactive compounds; food processing
(This special issue belongs to the Section Flavours and Fragrances)
Chemical Characterisation and Biological Evaluation of Bioactive Extracts and Functional Ingredients from Agro-Food By-Products
edited by Anca Becze
submission deadline 31 Jan 2027 | Viewed by 47 | Submission Open
Keywords: agro-food by-products; compositional profiling; bioactive compounds; extraction and valorisation; functional food ingredients; antioxidant and antimicrobial activity
(This special issue belongs to the Section Food Chemistry)
Production of Artemisia and Its Pharmacology vs. Artemisinin
edited by and Yuliang Wang
submission deadline 31 Jan 2027 | Viewed by 47 | Submission Open
Keywords: Artemisia annua; Artemisia afra; synergism; infectious and chronic diseases; phytochemistry; artemisinin biosynthesis
(This special issue belongs to the Section Natural Products Chemistry)
Aromatic Heterocyclic Compounds: From Synthesis to Biological Activities Research submission deadline 31 Jan 2027 | Viewed by 46 | Submission Open
Keywords: aromatic heterocycles; organic synthesis; medicinal chemistry; bioactive scaffolds; SAR; synthetic methodologies
(This special issue belongs to the Section Organic Chemistry)
Research Progress on Functional Lipids and Their Applications in Health Food Systems—2nd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 27 | Submission Open
Keywords: lipid crystallization; lipid oxidation; enzymatic lipid modification; processing; health benefits; structured emulsions; lipid emulsions; lipid capsules
(This special issue belongs to the Section Food Chemistry)
Phenolic Compounds from Foods: Extraction, Characterization, and Biological Activity submission deadline 31 Jan 2027 | Viewed by 24 | Submission Open
Keywords: phenolic compounds; food extracts; extraction techniques; chemical characterization; biological activity; antioxidant properties
(This special issue belongs to the Section Food Chemistry)
Research Advances in Rotational Spectroscopy: From Structures to Large Amplitude Motions of Molecules
edited by
submission deadline 31 Jan 2027 | Viewed by 9 | Submission Open
Keywords: rotational spectroscopy; microwave spectroscopy; large amplitude motion; structure determination; non-covalent interaction; nuclear quadrupole coupling
(This special issue belongs to the Section Molecular Structure)
Design and Applications of Phase Change Materials for Energy Storage and Conversion
edited by and Yinsheng Yu
submission deadline 31 Jan 2027 | Viewed by 6 | Submission Open
Keywords: phase change materials; materials chemistry; energy conversion and storage; thermally conductive composites; microencapsulation and interfacial engineering
(This special issue belongs to the Section Materials Chemistry)
Biochar in Environmental Chemistry: Mechanisms, Reactivity, and Applications submission deadline 31 Jan 2027 | Viewed by 5 | Submission Open
Keywords: biochar; environmental chemistry; sorption mechanisms; reactivity; pollutant transformation; advanced oxidation processes; carbon sequestration; soil remediation; water treatment
(This special issue belongs to the Section Green Chemistry)
Advances in Phenolic Compounds: Isolation, Characterization, and Bioapplications
edited by Didem Deliorman Orhan and
submission deadline 31 Jan 2027 | Viewed by 2 | Submission Open
Keywords: phenolic compounds; polyphenols; natural products; bioactive compounds; green extraction; functional foods; nutraceuticals
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Analytical Approaches and Chemical Profiling of Essential Oils: From Composition to Bioactivity
edited by
submission deadline 31 Jan 2027 | Submission Open
Keywords: essential oils; novel analytical approaches; metabolomics; chemometrics; chemical profiling; bioactivity; volatile terpenes; phenylpropanoids
(This special issue belongs to the Section Natural Products Chemistry)
Recent Trends in Pharmaceutical Analysis for Drug Development, Therapeutic Monitoring and Biomarker Discovery submission deadline 15 Feb 2027 | Viewed by 317 | Submission Open
Keywords: pharmaceutical analysis; bioanalysis; drug development; therapeutic monitoring; biomarker discovery; omics; toxicological analysis
(This special issue belongs to the Section Medicinal Chemistry)
Natural Compounds for Disease and Health, 4th Edition submission deadline 15 Feb 2027 | 1 articles | Viewed by 309 | Submission Open
Keywords: natural products; phytochemistry; structure– activity relationship; mechanisms of action; anti-aging; cancer; cardiovascular diseases; digestive diseases; endocrine disorders; immune diseases; infections; inflammation; liver diseases; metabolic diseases; musculoskeletal diseases; neurodegenerative diseases; pain; psychiatric diseases; renal diseases; respiratory diseases
(This special issue belongs to the Section Natural Products Chemistry)
Bioactive Compounds in Olive Oil: Biosynthesis, Transformations, and Health Effects submission deadline 28 Feb 2027 | Viewed by 422 | Submission Open
Keywords: virgin olive oil; olive oil bioactives; volatile compounds and aroma profile; biosynthesis and transformation of olive oil bioactives; olive oil production and processing chain; oxidative stability and antioxidant activity; sensory quality attributes; bioavailability and health-related effects
(This special issue belongs to the Section Food Chemistry)
Molecular Conformational Diversity submission deadline 28 Feb 2027 | Viewed by 150 | Submission Open
Keywords: conformational diversity; conformational ensemble; conformational flexibility; conformational sampling; energy landscape; protein dynamics; structural heterogeneity; intrinsically disordered proteins; molecular recognition; ligand binding; protein– protein interactions
(This special issue belongs to the Section Chemical Biology)
Electroanalysis of Biochemistry and Material Chemistry—3rd Edition
edited by Guangjin Wang
submission deadline 28 Feb 2027 | Viewed by 83 | Submission Open
Keywords: voltammetry; potentiometry; conductometry; electrolytic method; electrochemical biosensors; fuel cells; batteries; supercapacitors
(This special issue belongs to the Section Electrochemistry)
Advances in Target-Based Drug Design, Discovery and Screening
edited by Guang Huang
submission deadline 28 Feb 2027 | Viewed by 29 | Submission Open
Keywords: structure-based drug design; synthesis; target-based drug discovery; virtual screening; inhibitors; PROTACs; degraders; kinases; epigenetic targets
(This special issue belongs to the Section Medicinal Chemistry)
Small Molecules for Gonadal Diseases
edited by
submission deadline 28 Feb 2027 | Viewed by 13 | Submission Open
Keywords: small molecules; gonadal diseases; polycystic ovary syndrome; testicular dysfunction; prostate diseases; oxidative stress; inflammation; reproductive biology
(This special issue belongs to the Section Medicinal Chemistry)
The Role of Transition Metal Compounds in Energy Conversion
edited by , and
submission deadline 31 Mar 2027 | Viewed by 335 | Submission Open
Keywords: carrier density; electrode materials; energy conversion and storage; layered transition metal dichalcogenides; porous materials; MXene; fuel cells; batteries; supercapacitors; hydrogen production; energy storage and distribution; CO2 reduction
(This special issue belongs to the Section Electrochemistry)
Exploring Microorganisms and Their Bioactive Secondary Metabolites: From Nature to Application, 2nd Edition submission deadline 31 Mar 2027 | Viewed by 148 | Submission Open
Keywords: natural products; bioactive compounds; microbial secondary metabolites; biological activity; chemical composition; biosynthetic pathways; strategies for discovery; mechanisms of action; biotechnological potential; therapeutic applications
(This special issue belongs to the Section Natural Products Chemistry)
Novel Nanomaterials for Drug Delivery and Cancer Therapy
edited by and
submission deadline 31 Mar 2027 | Viewed by 94 | Submission Open
Keywords: nanomaterials; nanomedicine; drug delivery systems; cancer therapy; targeted delivery; translational nanotechnology
(This special issue belongs to the Section Nanochemistry)
CO2 Adsorption and Climatic Mitigation: Advanced Materials and Sustainable Technologies
edited by , Müslüm Demir and Suleyman Gokhan Colak
submission deadline 31 Mar 2027 | Viewed by 88 | Submission Open
Keywords: CO2 adsorption; carbon capture; climate change mitigation; metal– organic frameworks (MOFs); porous materials; advanced nanomaterials; carbon capture technologies; sustainable materials
(This special issue belongs to the Section Materials Chemistry)
Exploring Advanced Protein Inhibitors Based on Heterocyclic Scaffolds submission deadline 31 Mar 2027 | Viewed by 71 | Submission Open
Keywords: organic synthesis; drug design; heterocyclic compounds; computational studies; protein inhibitors; pharmacological evaluation; therapeutic application
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Adsorbents for Environmental Pollution and Resource Recycling—2nd Edition
edited by Lang Yang and Wei Wang
submission deadline 31 Mar 2027 | Viewed by 64 | Submission Open
Keywords: adsorption; molecular structure design; environmental pollution; metal enrichment extraction; resource recycling; adsorbent preparation and synthesis; wastewater treatment
(This special issue belongs to the Section Green Chemistry)
Environment and Energy-Related Photochemistry and Photocatalysis—A Theme Issue in Honor of Professor Pierre Pichat
edited by Matthew A. Tarr
submission deadline 31 Mar 2027 | Viewed by 56 | Submission Open
Keywords: photocatalysis: mechanisms; materials; reactors; photoelectrochemistry; environmental photocatalysis and photochemistry; photon-involving; energy-related chemical reactions; photochemistry of nanomaterials
(This special issue belongs to the Section Photochemistry)
Advanced Functional Materials for Thermal Management, Smart Wearables and Energy Saving
edited by Fujuan Liu
submission deadline 31 Mar 2027 | Viewed by 46 | Submission Open
Keywords: thermal insulation; smart wearables; thermal management; energy efficiency; intelligent textiles; bio-based materials; porous composites; sustainable development; building energy conservation
(This special issue belongs to the Section Materials Chemistry)
Multifunctional Coatings and Films Based on Nanomaterials submission deadline 31 Mar 2027 | Viewed by 43 | Submission Open
Keywords: tribology; wettability; nanomaterials; physicochemical diagnostics; antibacterial properties
(This special issue belongs to the Section Materials Chemistry)
Carbon Materials for Biomedical and Environmental Applications
edited by
submission deadline 31 Mar 2027 | Viewed by 37 | Submission Open
Keywords: carbon materials; biomedical applications; environmental applications; carbon based composites; catalysts; synthesis
(This special issue belongs to the Section Materials Chemistry)
Functional Molecules from Cannabis and Psilocybe: Synthesis, Chemistry, and Mechanistic Insights
edited by
submission deadline 31 Mar 2027 | Viewed by 29 | Submission Open
Keywords: cannabinoids; psilocybin; psilocin; synthesis; purification; structural elucidation; bioactivity; structure– activity relationships
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Phytochemical Analysis of Plant-Derived Bioactive Natural Products
edited by
submission deadline 31 Mar 2027 | Viewed by 20 | Submission Open
Keywords: phytochemical analysis; plant-derived bioactive compounds; natural products chemistry; polyphenols; metabolite profiling; sustainable plant matrices; circular economy valorization; agro-industrial by-products; nutraceutical applications; structure– activity relationships
(This special issue belongs to the Section Natural Products Chemistry)
Quantum Chemistry of the f-Elements
edited by
submission deadline 15 Apr 2027 | Viewed by 19 | Submission Open
Keywords: lanthanides; actinides; electronic structure; compounds; relativistic effects; multireference electron correlation methods; density functional theory
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Advances in Small-Molecule Cancer Therapeutics: Current Challenges and Future Perspectives
edited by and Gülşen Akalın Çiftçi
submission deadline 30 Apr 2027 | Viewed by 92 | Submission Open
Keywords: cancer; targeted therapy; anticancer drug discovery; lead identification; small molecules; cancer-related targets; signaling pathways in cancer; emerging approaches to anticancer drug design; targeted drug delivery
(This special issue belongs to the Section Medicinal Chemistry)
Magnetic Nanomaterials: Design, Properties and Potential Applications
edited by , Katarzyna Błoch and
submission deadline 30 Jun 2027 | Viewed by 172 | Submission Open
Keywords: magnetism; magnetic nanomaterials; nanoparticles; nanowires; nanotubes; nanoribbons; thin films; molecular magnets; design and synthesis of magnetic materials; characterization of magnetic materials; theoretical modeling and simulations of magnetic materials; applications of magnetic materials
(This special issue belongs to the Section Materials Chemistry)
Valorization Strategies for Plant-Based By-Products
edited by and Beenish Saba
submission deadline 30 Jun 2027 | Viewed by 27 | Submission Open
Keywords: valorization; biorefinery; bioeconomy; sustainability; circularity; upcycling; bioconversion; biomass; extraction; fermentation; bioprocessing; residues
(This special issue belongs to the Section Green Chemistry)
Advances in Nanoparticulate Drug Delivery Systems for Targeted Therapy submission deadline 31 Dec 2027 | 1 articles | Viewed by 776 | Submission Open
Keywords: nanocarriers; green synthesis; surface functionalization; stimulus-responsive systems; enhanced permeation and retention (EPR) effect; cell-membrane coating; ligand– receptor interactions; small-molecule ligands; biocompatibility; precision medicine
(This special issue belongs to the Section Nanochemistry)
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