Recent Advances in the Development of Nano-Biomaterials

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 467

Special Issue Editors


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Guest Editor
Department of Biological Applications and Technology, University of Ioannina, 45110 Ioannina, Grecee
Interests: nanobiocatalysts; bionanoassemblies; bionanodevices; “green” biocatalytic processes; enzymatic and microbial biotransformations
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Guest Editor
Department of Biological Applications and Technologies, University of Ioannina, 45110 Ioannina, Greece
Interests: nanobiocatalysis; nanobiotechnology; nanostructures; carbon nanomaterials

Special Issue Information

Dear Colleagues,

Nano-biomaterials are identified as biomaterials (including carbon-based nanomaterials, polymers, metals, ceramic, and composites) with constituent or surface feature sizes less than 100 nm and are being researched as potential alternatives to conventional nanomaterials for biological applications. These nanoscale biomaterials can be produced by living organisms, mainly microbes, or derived from natural sources, such as plant extracts and agricultural wastes. Moreover, functionalized conventional nanomaterials through the encapsulation or immobilization of biological macromolecules, such as enzymes and other proteins, can also be labeled as nano-biomaterials, considering the impacts of biomolecules on a nanomaterial’s parental characteristics and properties. The unique properties of nanoscale biomaterials, along with their enhanced biocompatibility, bioavailability, bioreactivity, and low or negligible toxicity, overcome scientific and medical challenges, thus making them an attractive research direction in a vast variety of biomedical and biotechnological applications. This Special Issue of Nanomaterials aims to review the current state of the art for nano-biomaterials research, welcoming review articles and original papers that deal with the synthesis, characterization, and properties of nanoscale biomaterials. This Special Issue will also emphasize prospective applications of nano-biomaterials in biomedical and biotechnological fields, covering drug or gene delivery, tissue engineering, implant design, disease treatment, bioimaging, biosensing, and biocatalysis.

Prof. Dr. Haralambos Stamatis
Dr. Michaela Patila
Guest Editors

Manuscript Submission Information

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Keywords

  • nano-biomaterials
  • nano-biomaterials synthesis and properties
  • design and fabrication of nano-biomaterials
  • drug or gene delivery
  • biosensing
  • bioimaging
  • biocatalysis

Published Papers (1 paper)

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Research

16 pages, 4155 KiB  
Article
New 3D Vortex Microfluidic System Tested for Magnetic Core-Shell Fe3O4-SA Nanoparticle Synthesis
by Adelina-Gabriela Niculescu, Oana Maria Munteanu (Mihaiescu), Alexandra Cătălina Bîrcă, Alina Moroșan, Bogdan Purcăreanu, Bogdan Ștefan Vasile, Daniela Istrati, Dan Eduard Mihaiescu, Tony Hadibarata and Alexandru Mihai Grumezescu
Nanomaterials 2024, 14(11), 902; https://doi.org/10.3390/nano14110902 (registering DOI) - 21 May 2024
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Abstract
This study’s main objective was to fabricate an innovative three-dimensional microfluidic platform suitable for well-controlled chemical syntheses required for producing fine-tuned nanostructured materials. This work proposes using vortex mixing principles confined within a 3D multilayered microreactor to synthesize magnetic core-shell nanoparticles with tailored [...] Read more.
This study’s main objective was to fabricate an innovative three-dimensional microfluidic platform suitable for well-controlled chemical syntheses required for producing fine-tuned nanostructured materials. This work proposes using vortex mixing principles confined within a 3D multilayered microreactor to synthesize magnetic core-shell nanoparticles with tailored dimensions and polydispersity. The newly designed microfluidic platform allowed the simultaneous obtainment of Fe3O4 cores and their functionalization with a salicylic acid shell in a short reaction time and under a high flow rate. Synthesis optimization was also performed, employing the variation in the reagents ratio to highlight the concentration domains in which magnetite is mainly produced, the formation of nanoparticles with different diameters and low polydispersity, and the stability of colloidal dispersions in water. The obtained materials were further characterized by X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy, dynamic light scattering (DLS), and transmission electron microscopy (TEM), with the experimental results confirming the production of salicylic acid-functionalized iron oxide (Fe3O4-SA) nanoparticles adapted for different further applications. Full article
(This article belongs to the Special Issue Recent Advances in the Development of Nano-Biomaterials)
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