Electrospinning Nanofibers: Synthesis and Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: closed (25 July 2020) | Viewed by 3411

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Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11052, Taiwan
Interests: medical devcies; dental materials; biomimetics; hydrogels; silk proteins.
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Special Issue Information

Dear Colleagues,

Electrospinning is a modern and efficient method which uses an electric field to produce fine fibers of a diameter down to nanoscale even with milligrams of materials. It encompasses the utilization of various small molecules/biomolecules, synthetic or natural polymers, ceramics, or their combinations/composites for nanofiber production at a mass scale. Fiber-shaped nanostructures with a tunable porosity, high specific surface area, and a flexibility of functionalization with biological molecules are its advantages. These spun fibers have wide applications in industry and biomedical areas, such as energy, catalysis, water treatment, aerospace, batteries, sensors, and electronic devices, filtration, composites, would dressing, tissue engineering scaffolds, and drug delivery. This Special Issue aims to enclose the most innovative advancements in the field of electrospinning of materials and fabrication processes. Furthermore, this may serve as a potent platform for knowledge sharing on the advancements in novel technologies and applications.

Prof. Dr. Jen-Chang Yang
Guest Editor

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Published Papers (1 paper)

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Research

17 pages, 2401 KiB  
Article
Mechanical Properties of Electrospun, Blended Fibrinogen: PCL Nanofibers
by Jacquelyn M. Sharpe, Hyunsu Lee, Adam R. Hall, Keith Bonin and Martin Guthold
Nanomaterials 2020, 10(9), 1843; https://doi.org/10.3390/nano10091843 - 15 Sep 2020
Cited by 17 | Viewed by 3126
Abstract
Electrospun nanofibers manufactured from biocompatible materials are used in numerous bioengineering applications, such as tissue engineering, creating organoids or dressings, and drug delivery. In many of these applications, the morphological and mechanical properties of the single fiber affect their function. We used a [...] Read more.
Electrospun nanofibers manufactured from biocompatible materials are used in numerous bioengineering applications, such as tissue engineering, creating organoids or dressings, and drug delivery. In many of these applications, the morphological and mechanical properties of the single fiber affect their function. We used a combined atomic force microscope (AFM)/optical microscope technique to determine the mechanical properties of nanofibers that were electrospun from a 50:50 fibrinogen:PCL (poly-ε-caprolactone) blend. Both of these materials are widely available and biocompatible. Fibers were spun onto a striated substrate with 6 μm wide grooves, anchored with epoxy on the ridges and pulled with the AFM probe. The fibers showed significant strain softening, as the modulus decreased from an initial value of 1700 MPa (5–10% strain) to 110 MPa (>40% strain). Despite this extreme strain softening, these fibers were very extensible, with a breaking strain of 100%. The fibers exhibited high energy loss (up to 70%) and strains larger than 5% permanently deformed the fibers. These fibers displayed the stress–strain curves of a ductile material. We provide a comparison of the mechanical properties of these blended fibers with other electrospun and natural nanofibers. This work expands a growing library of mechanically characterized, electrospun materials for biomedical applications. Full article
(This article belongs to the Special Issue Electrospinning Nanofibers: Synthesis and Applications)
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