Fluorescent Nanomaterials and Their Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 8950

Special Issue Editors


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Guest Editor
Honorary Australian Research Fellow, School of Physics, University of Melbourne, Parkville, VIC 3010, Australia
Interests: optical imaging; fluorescence; nanomaterials; biomaterials

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Guest Editor
Vice Chancellor Fellow, School of Science, Engineering and Health, RMIT University, Melbourne, VIC 3001, Australia
Interests: nano-optics; fluorescence; confocal microscopy; diamond optics; silk biopolymer

Special Issue Information

Dear Colleagues,

In the last few years, the study of fluorescent nanomaterials has become a distinctive subject of research. This increase in interest is driven by the numerous applications of these materials in industry, medicine, information technology, energy storage, sensing, and many others. Compared to traditional fluorescent molecules, fluorescent nanomaterials display many advantages, such as photostability, tunable morphology and size, as well as the ability to perform multiple functions. Many kinds of fluorescent nanomaterials are currently available, including diamond, metal-oxides, polymer, silica carbide, carbon, just to mention some. They are fabricated in many different shapes and sizes, and have a wide range of properties suitable for many different applications, ranging from quantum to biomedical applications. However, despite significant progress, obstacles remain in their successful implementation as industrial and clinical solutions. The full potential of these nanomaterials is yet to be employed for applications.

The overarching goal of this Special Issue is to tackle all recent advances in the development, characterization, and translational applications of fluorescent nanomaterials to real-life applications. The interdisciplinary aspect of this Issue is open to all aspects of fluorescent nanomaterials-related research, and it welcomes full-size articles, short communications, and reviews.

Dr. Snjezana Tomljenovic-Hanic
Dr. Asma Khalid
Guest Editors

Manuscript Submission Information

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Keywords

  • fluorescence
  • nanomaterials
  • fabrication
  • imaging
  • applications

Published Papers (2 papers)

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Research

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20 pages, 5952 KiB  
Article
Silk Fibroin Coated Magnesium Oxide Nanospheres: A Biocompatible and Biodegradable Tool for Noninvasive Bioimaging Applications
by Jitao Li, Asma Khalid, Rajni Verma, Amanda Abraham, Farah Qazi, Xiuxiu Dong, Gaofeng Liang and Snjezana Tomljenovic-Hanic
Nanomaterials 2021, 11(3), 695; https://doi.org/10.3390/nano11030695 - 10 Mar 2021
Cited by 23 | Viewed by 2613
Abstract
Fluorescent nanoparticles (NPs) have been increasingly studied as contrast agents for better understanding of biological processes at the cellular and molecular level. However, their use as bioimaging tools is strongly dependent on their optical emission as well as their biocompatibility. This work reports [...] Read more.
Fluorescent nanoparticles (NPs) have been increasingly studied as contrast agents for better understanding of biological processes at the cellular and molecular level. However, their use as bioimaging tools is strongly dependent on their optical emission as well as their biocompatibility. This work reports the fabrication and characterization of silk fibroin (SF) coated magnesium oxide (MgO) nanospheres, containing oxygen, Cr3+ and V2+ related optical defects, as a nontoxic and biodegradable hybrid platform for bioimaging applications. The MgO-SF spheres demonstrated enhanced emission efficiency compared to noncoated MgO NPs. Furthermore, SF sphere coating was found to overcome agglomeration limitations of the MgO NPs. The hybrid nanospheres were investigated as an in vitro bioimaging tool by recording their cellular uptake, trajectories, and mobility in human skin keratinocytes cells (HaCaT), human glioma cells (U87MG) and breast cancer cells (MCF7). Enhanced cellular uptake and improved intracellular mobilities of MgO-SF spheres compared to MgO NPs was demonstrated in three different cell lines. Validated infrared and bright emission of MgO-SF NP indicate their prospects for in vivo imaging. The results identify the potential of the hybrid MgO-SF nanospheres for bioimaging. This study may also open new avenues to optimize drug delivery through biodegradable silk and provide noninvasive functional imaging feedback on the therapeutic processes through fluorescent MgO. Full article
(This article belongs to the Special Issue Fluorescent Nanomaterials and Their Applications)
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Review

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23 pages, 2603 KiB  
Review
Surface Modification of Fluorescent Nanodiamonds for Biological Applications
by Hak-Sung Jung and Keir C. Neuman
Nanomaterials 2021, 11(1), 153; https://doi.org/10.3390/nano11010153 - 9 Jan 2021
Cited by 35 | Viewed by 5540
Abstract
Fluorescent nanodiamonds (FNDs) are a new class of carbon nanomaterials that offer great promise for biological applications such as cell labeling, imaging, and sensing due to their exceptional optical properties and biocompatibility. Implementation of these applications requires reliable and precise surface functionalization. Although [...] Read more.
Fluorescent nanodiamonds (FNDs) are a new class of carbon nanomaterials that offer great promise for biological applications such as cell labeling, imaging, and sensing due to their exceptional optical properties and biocompatibility. Implementation of these applications requires reliable and precise surface functionalization. Although diamonds are generally considered inert, they typically possess diverse surface groups that permit a range of different functionalization strategies. This review provides an overview of nanodiamond surface functionalization methods including homogeneous surface termination approaches (hydrogenation, halogenation, amination, oxidation, and reduction), in addition to covalent and non-covalent surface modification with different functional moieties. Furthermore, the subsequent coupling of biomolecules onto functionalized nanodiamonds is reviewed. Finally, biomedical applications of nanodiamonds are discussed in the context of functionalization. Full article
(This article belongs to the Special Issue Fluorescent Nanomaterials and Their Applications)
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