Nanomaterials Applied in Regenerative Healing and Scar Free Healing Current Concepts and Future Perspectives

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 6134

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Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania
Interests: inorganic materials; re-generating (raw) materials; end-of-life products; innovative bionanomaterials; transmission electron microscopy
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Special Issue Information

Dear Colleagues,

Among its numerous functions, the skin is mainly responsible for maintaining the structural and physiological barrier between an organism’s internal and external environment. As the first line of defense against external threats, the skin is injured more frequently than any other tissue and the damage, while repairable, leads to permanent scarring in mammals. In domestic animals and humans, scarring on the skin after surgery, trauma, burn, or sports injury is a major medical problem, generally resulting in adverse aesthetics, loss of function, restriction of tissue movement, and/or growth and adverse psychological effects. The main objective of this Special Issue is to collect the knowledge for the prevention and/or treatment of dermal scarring because the current treatments are empirical, unreliable, and unpredictable.

Dr. Bogdan Stefan Vasile
Guest Editor

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Keywords

  • Nanomaterials used in tissue regeneration
  • Tissue engineering
  • Skin regeneration
  • Nanobiomaterials for skin regeneration
  • Multifunctional materials
  • Naturally derived materials
  • Natural polymers
  • Synthetic polymers
  • Growth factor
  • Stem-cells
  • Cell delivery systems
  • Drug delivery systems
  • Extracellular matrix (ECM)
  • Wound healing
  • Scarring
  • Scar-free wound regeneration
  • Regenerative capacity

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Published Papers (1 paper)

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18 pages, 3672 KiB  
Review
Scar-Free Healing: Current Concepts and Future Perspectives
by Alexandra Elena Stoica, Alexandru Mihai Grumezescu, Anca Oana Hermenean, Ecaterina Andronescu and Bogdan Stefan Vasile
Nanomaterials 2020, 10(11), 2179; https://doi.org/10.3390/nano10112179 - 31 Oct 2020
Cited by 25 | Viewed by 5562
Abstract
Every year, millions of people develop scars due to skin injuries after trauma, surgery, or skin burns. From the beginning of wound healing development, scar hyperplasia, and prolonged healing time in wound healing have been severe problems. Based on the difference between adult [...] Read more.
Every year, millions of people develop scars due to skin injuries after trauma, surgery, or skin burns. From the beginning of wound healing development, scar hyperplasia, and prolonged healing time in wound healing have been severe problems. Based on the difference between adult and fetal wound healing processes, many promising therapies have been developed to decrease scar formation in skin wounds. Currently, there is no good or reliable therapy to cure or prevent scar formation. This work briefly reviews the engineering methods of scarless wound healing, focusing on regenerative biomaterials and different cytokines, growth factors, and extracellular components in regenerative wound healing to minimize skin damage cell types, and scar formation. Full article
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