Polymeric and Organic/Inorganic Hybrid Nano-Vehicles for the Delivery of Multiple Drugs and RNA
A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 4641
Special Issue Editor
Interests: pyrrole macrocycles for imaging and theranostics; nanoparticles for sensing applications and drug delivery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The combined administration of drugs and RNA has many potential applications in biomedicine for the treatment of genetic disorders and cancer. The general principle of combination therapy is the administration of more than one drug, with an independent mechanism of action, with the aim to enhance the efficiency of the treatment. For an optimal performance, the implementation of such therapies requires the delivery of the correct combination of drugs to a specific cellular target, which minimize undesirable side-effects. In this context, the use of polymeric and organic/inorganic hybrid nanoparticles as nano-vehicles for the co-delivery of multiple drugs have emerged as a promising strategy. However, although the use of such systems is promising, many challenges must be addressed in order to bring the benefits of this technology from the lab to the clinic.
This Special Issue is open to new advances in the application of polymeric and organic/inorganic hybrid nano-vehicles for multiple drugs and RNA delivery, involving:
- Design and preparation of polymeric or hybrid nano-vehicles
- Decoration of the nanoparticles using bio-conjugation technics
- Assessment of the stability, biocompatibility and safety of the nano-vehicles
- Study of the effective delivery of the drugs and RNA in vitro and in vivo
Prof. Dr. David Sánchez-García
Guest Editor
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Keywords
- polymeric nanoparticles
- hybrid nanoparticles
- RNA delivery
- Codelivery systems
- multipledrug resistance (MDR)
