Synthesis and Characterization of Nanofunctionalized Natural Hydrogels

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3807

Special Issue Editor


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Guest Editor
Université de Lorraine, Laboratoire d'Ingénierie des Biomolécules, 2 avenue de la Forêt de Haye, BP 20163, F-54505 Vandoeuvre-lès-Nancy, France
Interests: biopolymers; biomaterials; hydrogels; encapsulation of active compounds; nanoparticles; controlled release; nanomaterials for biomedical applications; biodegradable polymers for active packaging

Special Issue Information

Dear Colleagues,

Recently, hydrogels based on natural polymers have attracted considerable interest owing to their possible applications in different fields, such as biomedical, drug delivery, tissue engineering and regenerative medicine. They possess nontoxicity, high biocompatibility, biodegradability and similarity with native ECM. However, natural hydrogels do not always provide the biological and physicochemical properties required, but nanofunctionalization is a promising approach to modulate their properties. Soft and hard nanoparticles can be incorporated as fillers or reinforcing agents in the matrix. Hard nanoparticles (inorganic and metallic particles, quantum dots and carbon nanotubes) facilitate the modulation of local and global mechanical properties and electrical conductivity, while soft nanoparticles (liposomes, dendrimers, polymeric micelles and nanogels) allow the level of biological factors to be sustained.

In this Special Issue, we are especially interested in works that describe nanomaterials with applications in controlled release, tissue engineering or regenerative medicine. The format of welcomed articles includes reviews, communications and full papers.

The Special Issue will cover the synthesis, preparation, characterization and applications of functionalized hydrogels.

Dr. Laura Sánchez-González
Guest Editor

Manuscript Submission Information

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Keywords

  • biopolymers
  • hydrogels
  • biomaterials
  • nanofunctionalization
  • nanoparticles
  • biofabrication
  • nanomaterials for biomedical applications
  • drug delivery
  • controlled release
  • tissue engineering

Published Papers (1 paper)

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Research

10 pages, 1645 KiB  
Article
Physicochemical Interactions in Nanofunctionalized Alginate/GelMA IPN Hydrogels
by Rana Kadri, Kamil Elkhoury, Ghazi Ben Messaoud, Cyril Kahn, Ali Tamayol, Joao F. Mano, Elmira Arab-Tehrany and Laura Sánchez-González
Nanomaterials 2021, 11(9), 2256; https://doi.org/10.3390/nano11092256 - 31 Aug 2021
Cited by 16 | Viewed by 3258
Abstract
Polymeric hydrogels are currently at the center of research due to their particular characteristics. They have tunable physical, chemical, and biological properties making them a material of choice for a large range of applications. Polymer-composite and nanocomposite hydrogels were developed to enhance the [...] Read more.
Polymeric hydrogels are currently at the center of research due to their particular characteristics. They have tunable physical, chemical, and biological properties making them a material of choice for a large range of applications. Polymer-composite and nanocomposite hydrogels were developed to enhance the native hydrogel’s properties and to include numerous functionalities. In this work, alginate/gelatin-methacryloyl-based interpenetrating polymer network hydrogels were prepared with different alginate concentrations and investigated before and after the functionalization with nanoliposomes. The multiscale analysis was obtained through Fourier transform infrared spectroscopy and proton nuclear magnetic resonance. The results show interactions between two polymers as well as between the nanoliposomes and biopolymer. Full article
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