Nanomaterials for Photothermal Therapy and Antibacterial Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (20 May 2022) | Viewed by 4645

Special Issue Editor


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Guest Editor
National Formosa University Taiwan, Yunlin, Taiwan
Interests: Nanotechnology; Nanotherapeutics; Photothermal/photodynamic therapy; Nanotoxicology; Environmental Toxicology

Special Issue Information

Dear Colleagues,

Cancer and bacterial infectious disease have attracted considerable public attention due to their great threat to human health. In recent years, photothermal therapy (PTT) has been the object of growing interest, has undergone technological advances, and has been recognized as a non-invasive method to kill cancer cells and pathogenic bacteria. PTT requires the use of nanomaterials (e.g., gold nanoparticles, carbon nanomaterials, iron oxide nanoparticles, etc.) that exhibit high absorption in the near-infrared (NIR) region of the electromagnetic spectrum. The benefits of using nanomaterials is that the NIR light can be absorbed and rapidly converted into heat, thus increasing the surrounding temperature of the irradiated organisms.

We are launching a Special Issue of Nanomaterials entitled “Nanomaterials for Photothermal Therapy and Antibacterial Applications”. This Special Issue aims to cover different strategies against cancer and bacteria, improving the effect of phototherapy. We are particularly interested in the design of nanomaterials, and in the effects of their physico-chemical properties on their photothermal therapeutic efficiency in treating cancers and bacterial infections. We invite investigators to contribute review and original research papers reporting recent efforts in the field of nanomaterial-based photothermal therapies and antibacterial applications.

Dr. Chia-Hua Lin
Guest Editor

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Keywords

  • Nanomaterials
  • Photothermal therapy
  • Antibacterial
  • Anticancer
  • Nanotherapeutics

Published Papers (2 papers)

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Research

10 pages, 3901 KiB  
Article
Iron Hydroxide/Oxide-Reduced Graphene Oxide Nanocomposite for Dual-Modality Photodynamic and Photothermal Therapy In Vitro and In Vivo
by Wei-Jane Chiu, Yi-Chun Chen, Chih-Ching Huang, Lingyan Yang, Jiantao Yu, Shih-Wei Huang and Chia-Hua Lin
Nanomaterials 2021, 11(8), 1947; https://doi.org/10.3390/nano11081947 - 28 Jul 2021
Cited by 14 | Viewed by 3061
Abstract
Minimal invasive phototherapy utilising near-infrared (NIR) laser to generate local reactive oxygen species (ROS) and heat has few associated side effects and is a precise treatment in cancer therapy. However, high-efficiency and safe phototherapeutic tumour agents still need developing. The application of iron [...] Read more.
Minimal invasive phototherapy utilising near-infrared (NIR) laser to generate local reactive oxygen species (ROS) and heat has few associated side effects and is a precise treatment in cancer therapy. However, high-efficiency and safe phototherapeutic tumour agents still need developing. The application of iron hydroxide/oxide immobilised on reduced graphene oxide (FeOxH–rGO) nanocomposites as a therapeutic agent in integration photodynamic cancer therapy (PDT) and photothermal cancer therapy (PTT) was discussed. Under 808 nm NIR irradiation, FeOxH–rGO offers a high ROS generation and light-to-heat conversion efficiency because of its strong NIR absorption. These phototherapeutic effects lead to irreversible damage in FeOxH–rGO-treated T47D cells. Using a tumour-bearing mouse model, NIR ablated the breast tumour effectively in the presence of FeOxH–rGO. The tumour treatment response was evaluated to be 100%. We integrated PDT and PTT into a single nanodevice to facilitate effective cancer therapy. Our FeOxH–rGO, which integrates the merits of FeOxH and rGO, displays an outstanding tumoricidal capacity, suggesting the utilization of this nanocomposites in future medical applications. Full article
(This article belongs to the Special Issue Nanomaterials for Photothermal Therapy and Antibacterial Applications)
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17 pages, 5180 KiB  
Article
Iron Modified Titanate Nanotube Arrays for Photoelectrochemical Removal of E. coli
by Chia-Hung Chen, Yen-Ping Peng, Ming-Hsun Lin, Ken-Lin Chang, Yung-Chang Lin and Jian Sun
Nanomaterials 2021, 11(8), 1944; https://doi.org/10.3390/nano11081944 - 28 Jul 2021
Cited by 2 | Viewed by 2042
Abstract
This study used iron modified titanate nanotube arrays (Fe/TNAs) to remove E. coli in a photoelectrochemical system. The Fe/TNAs was synthesized by the anodization method and followed by the square wave voltammetry electrochemical deposition (SWVE) method with ferric nitrate as the precursor. Fe/TNAs [...] Read more.
This study used iron modified titanate nanotube arrays (Fe/TNAs) to remove E. coli in a photoelectrochemical system. The Fe/TNAs was synthesized by the anodization method and followed by the square wave voltammetry electrochemical deposition (SWVE) method with ferric nitrate as the precursor. Fe/TNAs were characterized by SEM, XRD, XPS, and UV-vis DRS to investigate the surface properties and light absorption. As a result, the iron nanoparticles (NPs) were successfully deposited on the tubular structure of the TNAs, which showed the best light utilization. Moreover, the photoelectrochemical (PEC) properties of the Fe/TNAs were measured by current-light response and electrochemical impedance spectroscopy. The photocurrent of the Fe/TNAs-0.5 (3.5 mA/cm2) was higher than TNAs (2.0 mA/cm2) and electron lifetime of Fe/TNAs-0.5 (433.3 ms) were also longer than TNAs (290.3 ms). Compared to the photolytic (P), photocatalytic (PC), and electrochemical (EC) method, Fe/TNAs PEC showed the best removal efficiency for methyl orange degradation. Furthermore, the Fe/TNAs PEC system also performed better removal efficiency than that of photolysis method in E. coli degradation experiments. Full article
(This article belongs to the Special Issue Nanomaterials for Photothermal Therapy and Antibacterial Applications)
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