Super Resolution Optical Microscopy: Sensing and Imaging

Dear Colleagues,

Breaking the optical diffraction limit has been a longstanding challenge in studying the cellular- and molecularscale activities of living systems and the nanoscale dynamics of novel materials. Various super-resolution microscopies have been developed, of which the most successful is fluorescence labeling super-resolution microscopies (including stimulated emission depletion (STED), single-molecule localization microscopy (SMLM), and structured illumination microscopy (SIM)), which possess high contrast, signal-to-noise ratio, and specificity. Fluorescence labeling methods are very important for these microscopies. Complementary, label-free microscopies exploit the inherent physical properties of samples and fill the gap of fluorescence microscopies. The representatives include chemical microscopies, phase microscopy, interferometric light microscopies, and high-resolution light-field microscopies. In addition, newly developed optical materials and structures, such as optical waveguides, microsphere lenses, super oscillatory lenses, hyper lenses, and metasurfaces, also shine in this field. We will also observe the new computational approaches for achieving super-resolved microscopy.

This Special Issue aims to present an overview of cutting-edge research, results, and their applications. We welcome broad, visionary contributions in the form of short research reports as well as collections of reviews and accomplishments. We are excited to invite researchers to submit their contributions to this Special Issue. Topics include but are not limited to:

• Fluorescence super-resolution microscopies;
• Fluorescence labeling methods in super-resolution microscopy;
• Label-free super-resolution microscopies;
• Chemical super-resolution microscopies;
• Interferometric light microscopies;
• High-resolution light-field microscopies;
• Plasmonic-based super resolution microscopies;
• Microsphere-aided super resolution microscopies;
• Metasurface-aided super resolution microscopies;
• Optical waveguide-aided microscopies;
• New computational approaches for achieving super-resolved microscopy.

We look forward to receiving your contributions.

Dr. Yubing Han
Dr. Mingwei Tang 
Guest Editors

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• super-resolution microscopy
• computational approaches
• nanomaterials
• metamaterials