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Advances in Electrospun Nanofibers for Skin Regeneration

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Fibers".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 15

Special Issue Editor


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Guest Editor
Center for Rapid and Sustainable Product Development, Polytechnic of Leiria, 2430-028 Marinha Grande, Portugal
Interests: tissue engineering; electrospinning; skin regeneration; nanofibers; biomaterials; polymers; bioresponsive structures
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Special Issue Information

Dear Colleagues,

Electrospinning is one of the most promising biofabrication techniques for skin regeneration due to its versatility. It allows the use of various polymers and biomolecules and enables the combination of different materials through multiple processing approaches, such as blending, core–shell structures, and single- or multi-jet systems. Additionally, electrospun scaffolds effectively mimic the morphology of the skin's extracellular matrix (ECM), including random fiber deposition, fiber diameter, and inter-fiber spacing.

Moreover, electrospun wound dressings have demonstrated exceptional properties, such as promoting hemostasis, absorbing exudates, ensuring permeability, conforming to wound contours, and reducing scar formation. However, despite these advantages, electrospinning presents three key limitations:

  1. Its inherently two-dimensional structure, which restricts its application in full-thickness wounds.
  2. Limited biological cues, as native ECM comprises a variety of bioactive molecules that are challenging to replicate.
  3. Poor replication of transepithelial potential, which is crucial for mimicking the "current of injury" that sustains cell migration and promotes physiological wound healing.

This Special Issue aims to provide a platform for academic exchange among researchers working on advanced structures to overcome these challenges. As Guest Editors, we invite you to submit original research or review articles on this topic.

Dr. Juliana Rosa Dias
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrospun meshes
  • skin regeneration
  • wound healing
  • 3D electrospun-based structures
  • stimuli-responsive electrospun wound dressings
  • ECM composition mimicking

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Published Papers

This special issue is now open for submission.
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