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Prosthesis
Special Issues
Antiviral and Antimicrobial Surface Design Strategies
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Antiviral and Antimicrobial Surface Design Strategies

A special issue of Prosthesis (ISSN 2673-1592).

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 34337

Special Issue Editor

Dr. Ajay Vikram Singh

E-Mail Website
Guest Editor
Department of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany
Interests: materials engineering and antibacterial surfaces; toxicology; micropatterning; micro/nanorobotics; magnetic applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Since the outbreak of SARS COV-2 (Covid-19), the disease has spread rapidly around as the global pandemic. Considering Covid-19's potential threat, material scientists and engineers have been rushing to understand this novel virus' surface stability, which could lead to the creation of antiviral coatings that could substantially reduce the virus' stabilization on different surfaces, thereby reducing community transmission. Such solutions also fit in context with prosthetic/implant surfaces involving vascularized areas and oral cavity prostheses, particularly as potential routes to viral entry. This will be a great focus to develop anti-infective solutions in the post-corona era. To support current research and development in this field, the journal Prosthesis is launching this Special Issue entitled "Antiviral and antimicrobial surface design strategies" to provide an overview of published scientific knowledge with a focus on prosthesis and implant coating. This Special Issue aims to present research papers, brief correspondence, and reviews articles based on new approaches addressing problems and recent developments in surface modification techniques that function as antiviral and antibacterial coatings. Specifically, topics of interest include, but are not limited to papers dealing with materials coating (as aligned with Prosthesis' wide scope in the sense of epidemiological research on disabled conditions), antiviral and antibacterial surface construction on high-traffic objects such as elderly homes, hospitals, and doors and windows in public transportation. We are also open to considering the subjects and research on occupational hygiene and socio-medical aspects of prosthetic rehabilitation.

Dr. Ajay Vikram Singh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Prosthesis is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Antiviral
  • Antibacterial
  • Antimicrobial surface treatments
  • Biofilm
  • Micro/Nano topography
  • Nanocoatings
  • Antiviral treatment
  • Vocational hygiene
  • Infectious organism

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (4 papers)

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Review

20 pages, 1646 KiB  
Review
Contemporary Tools for the Cure against Pernicious Microorganisms: Micro-/Nanorobots
by Mustafa Sami Ozaydin, Lorin Doganturk, Fulden Ulucan-Karnak, Ozan Akdogan and Pelin Erkoc
Prosthesis 2022, 4(3), 424-443; https://doi.org/10.3390/prosthesis4030034 - 5 Aug 2022
Cited by 9 | Viewed by 4161
Abstract
One of the most pressing concerns to global public health is the emergence of drug-resistant pathogenic microorganisms due to increased unconscious antibiotic usage. With the rising antibiotic resistance, existing antimicrobial agents lose their effectiveness over time. This indicates that newer and more effective [...] Read more.
One of the most pressing concerns to global public health is the emergence of drug-resistant pathogenic microorganisms due to increased unconscious antibiotic usage. With the rising antibiotic resistance, existing antimicrobial agents lose their effectiveness over time. This indicates that newer and more effective antimicrobial agents and methods should be investigated. Many studies have shown that micro-/nanorobots exhibit promise in the treatment of microbial infections with their great properties, such as the intrinsic antimicrobial activities owing to their oxidative stress induction and metal ion release capabilities, and effective and autonomous delivery of antibiotics to the target area. In addition, they have multiple simultaneous mechanisms of action against microbes, which makes them remarkable in antimicrobial activity. This review focuses on the antimicrobial micro-/nanorobots and their strategies to impede biofilm formation, following a brief introduction of the latest advancements in micro-/nanorobots, and their implementations against various bacteria, and other microorganisms. Full article
(This article belongs to the Special Issue Antiviral and Antimicrobial Surface Design Strategies)
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Graphical abstract

54 pages, 9511 KiB  
Review
A Review on the Recent Advancements on Therapeutic Effects of Ions in the Physiological Environments
by Muhammad Awais, Aqsa Aizaz, Arooba Nazneen, Qurat ul Ain Bhatti, Memoona Akhtar, Abdul Wadood and Muhammad Atiq Ur Rehman
Prosthesis 2022, 4(2), 263-316; https://doi.org/10.3390/prosthesis4020026 - 20 Jun 2022
Cited by 15 | Viewed by 4714
Abstract
This review focuses on the therapeutic effects of ions when released in physiological environments. Recent studies have shown that metallic ions like Ag+, Sr2+, Mg2+, Mn2+, Cu2+, Ca2+, P+5, [...] Read more.
This review focuses on the therapeutic effects of ions when released in physiological environments. Recent studies have shown that metallic ions like Ag+, Sr2+, Mg2+, Mn2+, Cu2+, Ca2+, P+5, etc., have shown promising results in drug delivery systems and regenerative medicine. These metallic ions can be loaded in nanoparticles, mesoporous bioactive glass nanoparticles (MBGNs), hydroxyapatite (HA), calcium phosphates, polymeric coatings, and salt solutions. The metallic ions can exhibit different functions in the physiological environment such as antibacterial, antiviral, anticancer, bioactive, biocompatible, and angiogenic effects. Furthermore, the metals/metalloid ions can be loaded into scaffolds to improve osteoblast proliferation, differentiation, bone development, fibroblast growth, and improved wound healing efficacy. Moreover, different ions possess different therapeutic limits. Therefore, further mechanisms need to be developed for the highly controlled and sustained release of these ions. This review paper summarizes the recent progress in the use of metallic/metalloid ions in regenerative medicine and encourages further study of ions as a solution to cure diseases. Full article
(This article belongs to the Special Issue Antiviral and Antimicrobial Surface Design Strategies)
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Figure 1

28 pages, 5357 KiB  
Review
Nanotechnology-Based Antimicrobial and Antiviral Surface Coating Strategies
by Pelin Erkoc and Fulden Ulucan-Karnak
Prosthesis 2021, 3(1), 25-52; https://doi.org/10.3390/prosthesis3010005 - 1 Feb 2021
Cited by 99 | Viewed by 16417
Abstract
Biocontamination of medical devices and implants is a growing issue that causes medical complications and increased expenses. In the fight against biocontamination, developing synthetic surfaces, which reduce the adhesion of microbes and provide biocidal activity or combinatory effects, has emerged as a major [...] Read more.
Biocontamination of medical devices and implants is a growing issue that causes medical complications and increased expenses. In the fight against biocontamination, developing synthetic surfaces, which reduce the adhesion of microbes and provide biocidal activity or combinatory effects, has emerged as a major global strategy. Advances in nanotechnology and biological sciences have made it possible to design smart surfaces for decreasing infections. Nevertheless, the clinical performance of these surfaces is highly depending on the choice of material. This review focuses on the antimicrobial surfaces with functional material coatings, such as cationic polymers, metal coatings and antifouling micro-/nanostructures. One of the highlights of the review is providing insights into the virus-inactivating surface development, which might particularly be useful for controlling the currently confronted pandemic coronavirus disease 2019 (COVID-19). The nanotechnology-based strategies presented here might be beneficial to produce materials that reduce or prevent the transmission of airborne viral droplets, once applied to biomedical devices and protective equipment of medical workers. Overall, this review compiles existing studies in this broad field by focusing on the recent related developments, draws attention to the possible activity mechanisms, discusses the key challenges and provides future recommendations for developing new, efficient antimicrobial and antiviral surface coatings. Full article
(This article belongs to the Special Issue Antiviral and Antimicrobial Surface Design Strategies)
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Figure 1

23 pages, 8607 KiB  
Review
Functionalization of Polymers and Nanomaterials for Biomedical Applications: Antimicrobial Platforms and Drug Carriers
by Masoud Delfi, Matineh Ghomi, Ali Zarrabi, Reza Mohammadinejad, Zahra Baghban Taraghdari, Milad Ashrafizadeh, Ehsan Nazarzadeh Zare, Tarun Agarwal, Vinod V. T. Padil, Babak Mokhtari, Filippo Rossi, Giuseppe Perale, Mika Sillanpaa, Assunta Borzacchiello, Tapas Kumar Maiti and Pooyan Makvandi
Prosthesis 2020, 2(2), 117-139; https://doi.org/10.3390/prosthesis2020012 - 23 Jun 2020
Cited by 48 | Viewed by 7054
Abstract
The use of polymers and nanomaterials has vastly grown for industrial and biomedical sectors during last years. Before any designation or selection of polymers and their nanocomposites, it is vital to recognize the targeted applications which require these platforms to be modified. Surface [...] Read more.
The use of polymers and nanomaterials has vastly grown for industrial and biomedical sectors during last years. Before any designation or selection of polymers and their nanocomposites, it is vital to recognize the targeted applications which require these platforms to be modified. Surface functionalization to introduce the desired type and quantity of reactive functional groups to target a cell or tissue in human body is a pivotal approach to improve the physicochemical and biological properties of these materials. Herein, advances in the functionalized polymer and nanomaterials surfaces are highlighted along with their applications in biomedical fields, e.g., antimicrobial therapy and drug delivery. Full article
(This article belongs to the Special Issue Antiviral and Antimicrobial Surface Design Strategies)
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