CerviCo-Vaginal Dysbiosis as Risk Factor for Sexually Transmitted Diseases: Insights from Molecular Researches
A special issue of Reproductive Medicine (ISSN 2673-3897).
Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 397
Special Issue Editor
Interests: identification of host defence factors towards C. trachomatis genital infection; study of C. trachomatis role in the pathogenesis of male infertility; study of chlamydia-host cell interaction; identification of new anti-chlamydial drugs; study of the etiopathogenic role Chlamydia pneumoniae in the chronic inflammatory diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The genital microenvironment is an ecological niche characterized by a dynamic balance between numerous aerobic and anaerobic microorganisms that constitute the resident microbiota, widely considered as an important defense factor in the female genital tract against invading pathogens. In healthy women, the genital microbiota is typically dominated by several Lactobacillus species, conferring protection against infections through several mechanisms, such as competitive exclusion and the production of hydrogen peroxide and bacteriocins. By contrast, the depletion of lactobacilli and the overgrowth of a wide array of strict and facultative anaerobes—including Gardnerella vaginalis, Atopobium vaginae and Prevotella spp.—leads to a condition called dysbiosis that has been associated with an increased risk of sexually transmitted infections, such as Chlamydia trachomatis, Neisseria gonorrhoeae, HPV, HIV, etc.
This Special Issue aims to gather the most recent evidence on either genital dysbiosis as a risk factor for sexually transmitted infections or the protective activity of a lactobacillus-dominated microbiota. Studies on microbe-associated molecular patterns will also be considered. Overall, this will provide a more comprehensive picture of the multifaceted role of the cervico-vaginal microenvironment regarding infectious agents.
You may choose our Joint Special Issue in International Journal of Molecular Sciences.
Prof. Rosa Sessa
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Reproductive Medicine is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Sexually transmitted diseases
- Cervico-vaginal microbiota
- Dysbiosis
- Microbe-associated molecular patterns
- Next-generation sequencing
- Metabolomic
- Proteomic
