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Feature Review Papers in Biosensors Section 2024
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Feature Review Papers in Biosensors Section 2024

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 4802

Special Issue Editors

Dr. Igor Medintz

E-Mail Website
Guest Editor
US Naval Research Laboratory, 4555 Overlook Ac SW, Washington, DC 20375, USA
Interests: bionanotechnology; nanoparticle; energy transfer; enzyme; kinetics; cell-free synthetic biology; biocatalysis; bioconjugation
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Toshiyo Tamura

E-Mail Website
Guest Editor
Future Robotics Organization, Waseda University, Tokyo, Japan
Interests: bio instrumentation; bio signal interpretation; noninvasive monitor; unobtrusive sensing; blood pressure monitoring; healthcare system; assistive device; temperature regulation; heat stroke
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite submissions for the 2024 Special Issue titled "Feature Review Papers in Biosensors Section 2024".

This Special Issue aims to review the recent developments of advanced sensors and their applications in healthcare and clinical practice. Heavily impacted by the COVID-19 pandemic, the healthcare sector is witnessing the development and application of new technologies for diagnostics. Smarter, more accurate, faster, wireless, safer, self-learning, smaller, and standardized sensors are being widely developed and deployed. Many sensors that do not interfere with daily life and sensors made of new biocompatible materials have been attempted and are starting to be used clinically.

Potential topics include, but are not limited to, the following:

  • Sensors that predict and prevent disease and improve the quality of daily life;
  • Challenges and opportunities in the development of innovative sensing devices;
  • Biosensors for microelectromechanical systems (MEMSs) and nanoelectromechanical systems (NEMSs);
  • Wearable sensors and energy harvest;
  • Sensors with the rapid development of fifth-generation (5G) cellular network technology;
  • Key technologies influencing sensor design and innovation.

Dr. Igor Medintz
Prof. Dr. Toshiyo Tamura
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • noninvasive
  • unconstrained
  • optical
  • biochemical
  • physical MEMS/NEMS
  • wearable energy harvest
  • healthcare
  • clinical practice

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Published Papers (3 papers)

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Review

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31 pages, 2779 KiB  
Review
Emerging Sensing Technologies for Liquid Biopsy Applications: Steps Closer to Personalized Medicine
by Panagiota M. Kalligosfyri, Eleni Lamprou and Despina P. Kalogianni
Sensors 2024, 24(24), 7902; https://doi.org/10.3390/s24247902 - 11 Dec 2024
Viewed by 390
Abstract
Liquid biopsy is an efficient diagnostic/prognostic tool for tumor-derived component detection in peripheral circulation and other body fluids. The rapid assessment of liquid biopsy techniques facilitates early cancer diagnosis and prognosis. Early and precise detection of tumor biomarkers provides crucial information about the [...] Read more.
Liquid biopsy is an efficient diagnostic/prognostic tool for tumor-derived component detection in peripheral circulation and other body fluids. The rapid assessment of liquid biopsy techniques facilitates early cancer diagnosis and prognosis. Early and precise detection of tumor biomarkers provides crucial information about the tumor that guides clinicians towards effective personalized medicine. Point-of-care-testing remains still a great challenge in cancer diagnostics. Liquid biopsy is a promising alternative to tissue biopsy with the great advantages of less invasion and real-time monitoring of the disease, also providing information about tumor heterogeneity. The field is continuously and rapidly expanding. Numerous sophisticated biosensors have been developed targeting several biomarkers to achieve low detection limits, increased specificity and robustness. Current biosensors include mainly optical sensors, such as colorimetric, fluorescent, SPR, SERS and lateral flow assays. Electrochemical sensors have also been developed, providing very low detection limits. Colorimetric sensors exhibited simplicity in signal interpretation, while fluorescent sensors contributed to low analysis times, and SPR/SERS enabled label-free and rapid analysis. Novel target amplification and signal enhancement techniques have been exploited to increase the detectability of the sensors. In this context, this review is focused on the recent advances in biosensing technology for cutting-edge liquid biopsy applications towards point-of-care testing. Full article
(This article belongs to the Special Issue Feature Review Papers in Biosensors Section 2024)
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21 pages, 450 KiB  
Review
Noninvasive Electromagnetic Neuromodulation of the Central and Peripheral Nervous System for Upper-Limb Motor Strength and Functionality in Individuals with Cervical Spinal Cord Injury: A Systematic Review and Meta-Analysis
by Loreto García-Alén, Aina Ros-Alsina, Laura Sistach-Bosch, Mark Wright and Hatice Kumru
Sensors 2024, 24(14), 4695; https://doi.org/10.3390/s24144695 - 19 Jul 2024
Viewed by 1640
Abstract
(1) Background: Restoring arm and hand function is one of the priorities of people with cervical spinal cord injury (cSCI). Noninvasive electromagnetic neuromodulation is a current approach that aims to improve upper-limb function in individuals with SCI. The aim of this study is [...] Read more.
(1) Background: Restoring arm and hand function is one of the priorities of people with cervical spinal cord injury (cSCI). Noninvasive electromagnetic neuromodulation is a current approach that aims to improve upper-limb function in individuals with SCI. The aim of this study is to review updated information on the different applications of noninvasive electromagnetic neuromodulation techniques that focus on restoring upper-limb functionality and motor function in people with cSCI. (2) Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were used to structure the search protocol. A systematic review of the literature was performed in three databases: the Cochrane Library, PubMed, and Physiotherapy Evidence Database (PEDro). (3) Results: Twenty-five studies were included: four were on transcranial magnetic stimulation (TMS), four on transcranial direct current stimulation (tDCS), two on transcutaneous spinal cord stimulation (tSCS), ten on functional electrical stimulation (FES), four on transcutaneous electrical nerve stimulation (TENS), and one on neuromuscular stimulation (NMS). The meta-analysis could not be completed due to a lack of common motor or functional evaluations. Finally, we realized a narrative review of the results, which reported that noninvasive electromagnetic neuromodulation combined with rehabilitation at the cerebral or spinal cord level significantly improved upper-limb functionality and motor function in cSCI subjects. Results were significant compared with the control group when tSCS, FES, TENS, and NMS was applied. (4) Conclusions: To perform a meta-analysis and contribute to more evidence, randomized controlled trials with standardized outcome measures for the upper extremities in cSCI are needed, even though significant improvement was reported in each non-invasive electromagnetic neuromodulation study. Full article
(This article belongs to the Special Issue Feature Review Papers in Biosensors Section 2024)
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12 pages, 923 KiB  
Perspective
Safety of Immersive Virtual Reality for the Management of Parkinson’s Disease
by Daniela Pimenta Silva, Filipa Pona-Ferreira, Beatriz Santos, Pablo Campo-Prieto, Raquel Bouça-Machado and Joaquim J. Ferreira
Sensors 2024, 24(24), 8188; https://doi.org/10.3390/s24248188 - 22 Dec 2024
Viewed by 268
Abstract
Virtual reality (VR) has been used in research and clinical practice in the management of Parkinson’s disease (PD), potentially enhancing physiotherapy. Adverse events (AEs) associated with VR applications in PD have been poorly explored. We conducted a randomized controlled trial to compare two [...] Read more.
Virtual reality (VR) has been used in research and clinical practice in the management of Parkinson’s disease (PD), potentially enhancing physiotherapy. Adverse events (AEs) associated with VR applications in PD have been poorly explored. We conducted a randomized controlled trial to compare two 12-week interventions using physiotherapy and immersive VR, and analyzed the frequency and type of AEs occurring in 30 people with PD. We reported 144 AEs (8.4% of the sessions), predominantly classified as mild and unrelated to the interventions. Two were serious AEs, one leading to study discontinuation. Notably, discomfort/pain, motor fluctuations, and falls were the most frequently reported, accounting for 63% of the total AEs. Five falls were definitely associated with the ‘sense of presence’ provided by the fully immersive VR system, which underscores the necessity for careful game selection when designing interventions for PD. Motor fluctuations may have been associated with various factors, which merit further investigation. We also explored the role of SSQ as a measure of cybersickness in PD. In conclusion, it is important to closely monitor and characterize AEs to ensure safety and efficacy in clinical practice as AEs may be more common than previously recognized in VR interventions in PD. Full article
(This article belongs to the Special Issue Feature Review Papers in Biosensors Section 2024)
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