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Optical Sensors for Biological and Biomedical Applications

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Optical Sensors".

Deadline for manuscript submissions: 20 March 2025 | Viewed by 533

Special Issue Editor


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Guest Editor
Department of Electronics and Computer Technology, Escuela Técnica Superior de Ingenierías Informática y de Telecomunicación (ETSIIT), University of Granada, 18014 Granada, Spain
Interests: electronic instrumentation; optical sensors; environmental analysis; electrical capacitance tomography; multispectral analysis
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Special Issue Information

Dear Colleagues,

Optical sensors are based on the principle of light–matter interaction. Depending on the type of sensor, they can measure different properties of light, such as intensity, wavelength, polarization, phase, or frequency. They can also generate light signals using different sources, such as lasers, LEDs, or fluorescent molecules. Optical sensors have biomedical applications for detecting biomarkers and measuring physiological parameters such as blood pressure, oxygen saturation, glucose level, or temperature. They are also used for administering light-based therapies. Optical sensors have significant advantages over other types of sensors: they are non-invasive, biocompatible, versatile, sensitive, accurate, and fast. They can also be portable, implantable, or disposable.

In this Special Issue, the entire scientific community is invited to participate with their contributions addressing topics related to the design, application, improvement, and results of optical sensors for biological and biomedical applications.

Prof. Dr. Antonio Martínez Olmos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optical sensor
  • LED
  • photodetector
  • biological
  • biomedical

Published Papers (1 paper)

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Research

11 pages, 5345 KiB  
Article
Development and Assessment of Multiple Illumination Color Fourier Ptychographic Microscopy for High Throughput Sample Digitization
by Patrik Gilley, Ke Zhang, Neman Abdoli, Youkabed Sadri, Laura Adhikari, Kar-Ming Fung and Yuchen Qiu
Sensors 2024, 24(14), 4505; https://doi.org/10.3390/s24144505 - 12 Jul 2024
Viewed by 403
Abstract
In this study, we proposed a multiplexed color illumination strategy to improve the data acquisition efficiency of Fourier ptychography microscopy (FPM). Instead of sequentially lighting up one single channel LED, our method turns on multiple white light LEDs for each image acquisition via [...] Read more.
In this study, we proposed a multiplexed color illumination strategy to improve the data acquisition efficiency of Fourier ptychography microscopy (FPM). Instead of sequentially lighting up one single channel LED, our method turns on multiple white light LEDs for each image acquisition via a color camera. Thus, each raw image contains multiplexed spectral information. An FPM prototype was developed, which was equipped with a 4×/0.13 NA objective lens to achieve a spatial resolution equivalent to that of a 20×/0.4 NA objective lens. Both two- and four-LED illumination patterns were designed and applied during the experiments. A USAF 1951 resolution target was first imaged under these illumination conditions, based on which MTF curves were generated to assess the corresponding imaging performance. Next, H&E tissue samples and analyzable metaphase chromosome cells were used to evaluate the clinical utility of our strategy. The results show that the single and multiplexed (two- or four-LED) illumination results achieved comparable imaging performance on all the three channels of the MTF curves. Meanwhile, the reconstructed tissue or cell images successfully retain the definition of cell nuclei and cytoplasm and can better preserve the cell edges as compared to the results from the conventional microscopes. This study initially validates the feasibility of multiplexed color illumination for the future development of high-throughput FPM scanning systems. Full article
(This article belongs to the Special Issue Optical Sensors for Biological and Biomedical Applications)
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