Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.3
3.4
Journals
Sensors
Special Issues
Biomedical Sensors Based on Microfluidics
sensors-logo
Submit to Special Issue Submit Abstract to Special Issue Review for Sensors Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Biomedical Sensors Based on Microfluidics

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 2050

Special Issue Editors

Prof. Dr. Han-Sheng Chuang

E-Mail Website
Guest Editor
Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan
Interests: biosensing technology; optical sensors; lab-on-a-chip; microfluidics; optical diffusometry; bioMEMS
Special Issues, Collections and Topics in MDPI journals
Dr. Dhrubajyoti Das

E-Mail Website
Guest Editor
Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan
Interests: biosensors; rotational diffusometry; microfluidics; polymerase chain reaction; loop mediated isothermal amplification; microfabrication

Special Issue Information

Dear Colleagues,

The burgeoning interest in the development of biosensing devices with integrated microfluidic technology stems from their potential to significantly transform healthcare through the creation of miniaturized, portable solutions. By providing precise analysis of biological samples, these sensors facilitate early diagnostics, mass screening, ongoing monitoring, and tailored treatment approaches. Consequently, they are propelling noteworthy advancements in medical technology and enhancing patient care. This Special Issue endeavors to present leading-edge research in the development of medical, biomolecular, and biochemical sensors integrated with microfluidic platforms and their diverse applications in diagnostics, continuous monitoring, and personalized medicine. Topics of interest include, but are not limited to, the following: 

  • Electrochemical and chemical sensors;
  • Optical biosensors and biomedical imaging;
  • Acoustofluidic and piezoelectric devices;
  • Lab-on-a-chip and organ-on-a-chip devices;
  • Wearable devices;
  • Extracellular vesicles and nanoparticles;
  • Nano-biosensors, nanomaterials, and nanoanalytical systems;
  • Nucleic acid analysis and aptasensors;
  • Enzyme-based sensors and immunosensors;
  • CRISPER technique;
  • Polymers, synthetic receptors, and molecularly imprinted polymers;
  • Biomaterials and bioengineered sensors. 

Prof. Dr. Han-Sheng Chuang
Dr. Dhrubajyoti Das
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microfluidics
  • biosensors
  • lab-on-a-chip
  • point-of-care
  • diagnostics

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

7 pages, 931 KiB  
Communication
Development of Lasing Silica Microsphere for High-Speed DNA Molecular Detection
by Chan Seok Jun and Wonsuk Lee
Sensors 2024, 24(18), 6088; https://doi.org/10.3390/s24186088 - 20 Sep 2024
Viewed by 417
Abstract
Laser and molecular detection techniques that have been used to overcome the limitations of fluorescent DNA labeling have presented new challenges. To address some of these challenges, we developed a DNA laser that uses a solid-state silica microsphere as a ring resonator and [...] Read more.
Laser and molecular detection techniques that have been used to overcome the limitations of fluorescent DNA labeling have presented new challenges. To address some of these challenges, we developed a DNA laser that uses a solid-state silica microsphere as a ring resonator and a site for DNA-binding reactions, as well as a platform to detect and sequence target DNA molecules. We detected target DNA using laser emission from a DNA-labeling dye and a developed solid-state silica microsphere ring resonator. The microsphere was sensitive; a single base mismatch in the DNA resulted in the absence of an optical signal. As each individual microsphere can be utilized as a parallel DNA analysis chamber, this optical digital detection scheme allows for high-throughput and rapid analysis. More importantly, the solid-state DNA laser is free from deformation, which guarantees stable lasing characteristics, and can be manipulated freely outside the solution. Thus, this promising advanced DNA laser scheme can be implemented on platforms other than optofluidic chips. Full article
(This article belongs to the Special Issue Biomedical Sensors Based on Microfluidics)
►▼ Show Figures

Figure 1

15 pages, 2335 KiB  
Article
Looping Flexible Fluoropolymer Microcapillary Film Extends Analysis Times for Vertical Microfluidic Blood Testing
by Rüya Meltem Sarıyer, Kirandeep K. Gill, Sarah H. Needs, Nuno M. Reis, Chris I. Jones and Alexander Daniel Edwards
Sensors 2024, 24(18), 5870; https://doi.org/10.3390/s24185870 - 10 Sep 2024
Viewed by 1163
Abstract
The microfluidic measurement of capillary flow can be used to evaluate the response of biological samples to stimulation, where distance and velocity are altered. Melt-extruded multi-bored microfluidic capillaries allow for high-throughput testing with low device cost, but simple devices may limit control over [...] Read more.
The microfluidic measurement of capillary flow can be used to evaluate the response of biological samples to stimulation, where distance and velocity are altered. Melt-extruded multi-bored microfluidic capillaries allow for high-throughput testing with low device cost, but simple devices may limit control over sample flow when compared to the more complex “lab-on-a-chip” devices produced using advanced microfluidic fabrication methods. Previously, we measured the dynamics of global haemostasis stimulated by thrombin by dipping straight vertical microcapillaries into blood, but only the most rapid response could be monitored, as flow slowed significantly within 30 s. Here, we show an innovative method to extend both the stimulation process and flow measurement time without increasing the cost of the device by adding simple loops to the flexible extruded device. The loops enable longer time-scale measurements by increasing resistance to flow, thereby reducing the dependence on high stimulus concentrations for rapid reactions. The instantaneous velocity and equilibrium heights of straight and looped vertical microcapillary films were assessed with water, plasma and whole blood, showing that the loops create additional frictional resistances, reduce flow velocity and prolong residence times for increased time scales of the stimulation process. A modified pressure balance model was used to capture flow dynamics with the added loop. Looped devices loaded with thrombin and collagen showed an improved detection of blood stimulation responses even with lower stimulus concentrations, compared to straight vertical capillaries. Thrombin-activated blood samples in straight capillaries provided a maximum measurement zone of only 4 mm, while the looped design significantly increased this to 11 mm for much longer time scale measurements. Our results suggest that extending stimulation times can be achieved without complex microfluidic fabrication methods, potentially improving concentration–response blood stimulation assays, and may enhance the accuracy and reliability. We conclude adding a loop to low-cost extruded microfluidic devices may bring microfluidic devices closer to delivering on their promise of widespread, decentralized low-cost evaluation of blood response to stimulation in both research and clinical settings. Full article
(This article belongs to the Special Issue Biomedical Sensors Based on Microfluidics)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop