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Molecularly Imprinted Polymer Sensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Chemical Sensors".

Deadline for manuscript submissions: closed (15 March 2023) | Viewed by 2846

Special Issue Editor


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Guest Editor
Institute of Physical Chemistry PAS, Kasprzaka 44/52, 01-224 Warsaw, Poland
Interests: molecularly imprinted polymers; chemosensors; conductive polymers

Special Issue Information

Dear colleagues,

Recently, the application of molecularly imprinted polymers (MIPs) in devising selective chemosensors has been gaining more and more interest. This is because MIP chemosensors offer high selectivity and robustness and are relatively easily fabricated. Moreover, molecular imprinting can be readily combined with micro- and nanofabrication methods. This results in significant enhancement in the sensitivity of the devised chemosensors. As such, numerous examples of practical applications of MIP chemosensors in various fields were reported in the last decade.

This Special Issue aims to put together both original research and review articles on recent advances, applications, and challenges in the field of MIP sensors.

Potential topics of the Special Issue include but are not limited to:

  • MIP electrochemical sensors;
  • MIP microgravimetric chemosensors;
  • Application of localized and surface plasmon spectroscopy (LSPR and SPR) for devising MIP chemosensors;
  • Application of MIP nanoparticles in optical assays;
  • Novel MIP micro- and nanofabrication methods;
  • New, advanced polymers for MIP synthesis;
  • Application of MIP sensors in clinical analysis, including point-of-care (POC) devises;
  • Fluorescent MIPs for in vivo imaging;
  • MIP chemosensors for pharmaceutical or food products quality control;
  • MIP sensors in environmental studies.

Dr. Maciej Cieplak
Guest Editor

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Keywords

  • Molecularly imprinted polymers (MIPs)
  • Polymer nanoparticles
  • Porous polymers
  • Selective chemosensors
  • POC devises
  • Point-of-care devises
  • Biomarker detection
  • Confocal fluorescence microscopy for tissue imaging
  • Handheld sensors
  • Infield analysis
  • Optical assays

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Published Papers (1 paper)

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Research

13 pages, 7478 KiB  
Article
Molecularly Imprinted Nanoparticle Ensembles for Rapidly Identifying S. epidermidis
by Chularat Hlaoperm, Wisnu Arfian A. Sudjarwo, Jakob Ehrenbrandtner, Endre Kiss, Giorgia Del Favero, Kiattawee Choowongkomon, Jatuporn Rattanasrisomporn and Peter A. Lieberzeit
Sensors 2023, 23(7), 3526; https://doi.org/10.3390/s23073526 - 28 Mar 2023
Viewed by 2154
Abstract
Staphylococcus epidermidis (S. epidermidis) belongs to methicillin-resistant bacteria strains that cause severe disease in humans. Herein, molecularly imprinted polymer (MIP) nanoparticles resulting from solid-phase synthesis on entire cells were employed as a sensing material to identify the species. MIP nanoparticles revealed [...] Read more.
Staphylococcus epidermidis (S. epidermidis) belongs to methicillin-resistant bacteria strains that cause severe disease in humans. Herein, molecularly imprinted polymer (MIP) nanoparticles resulting from solid-phase synthesis on entire cells were employed as a sensing material to identify the species. MIP nanoparticles revealed spherical shapes with diameters of approximately 70 nm to 200 nm in scanning electron microscopy (SEM), which atomic force microscopy (AFM) confirmed. The interaction between nanoparticles and bacteria was assessed using height image analysis in AFM. Selective binding between MIP nanoparticles and S. epidermidis leads to uneven surfaces on bacteria. The surface roughness of S. epidermidis cells was increased to approximately 6.3 ± 1.2 nm after binding to MIP nanoparticles from around 1 nm in the case of native cells. This binding behavior is selective: when exposing Escherichia coli and Bacillus subtilis to the same MIP nanoparticle solutions, one cannot observe binding. Fluorescence microscopy confirms both sensitivity and selectivity. Hence, the developed MIP nanoparticles are a promising approach to identify (pathogenic) bacteria species. Full article
(This article belongs to the Special Issue Molecularly Imprinted Polymer Sensors)
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