Electrochemiluminescence Biosensor (ECL Biosensors)
A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".
Deadline for manuscript submissions: closed (26 October 2019) | Viewed by 4572
Special Issue Editor
Interests: electroanalytical chemistry; electrogenerated chemiluminescence (ECL); chemical sensors and biosensors based on electrochemical and ECL detections
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Electrogenerated chemiluminescence, also called electrochemiluminescence (ECL), is the light emission generated from molecular species (luminophores) via an electron transfer process. The main merits of ECL are its excellent selectivity, sensitivity, and simplicity, and the possibility of spatial and time control because the ECL is triggered by an electrochemical reaction of the luminophores on an electrode surface. Due to these merits of the ECL process, it has become an attractive transduction platform and has received growing interest not only in chemical sensors, but also in biosensors and bioassays. ECL-based biosensors use specific biological recognition elements such as oxidase or dehydrogenase enzymes, antibodies, aptamers, carbohydrate-binding lectins, peptides, and proteins to selectively recognize an analyte and produce an ECL signal change depending upon the analyte concentration. Some of these analytes include the substrates of enzymatic reactions, antigens, carbohydrates, peptides, nucleic acids, and living cells such as Escherichia coli or even cancer cells.
Over the past several decades, numerous studies on ECL biosensors and bioassays have been conducted in a variety of fields ranging from chemical analysis and clinical diagnostics to environmental, water, or food analysis. In addition, a number of new luminophores—mostly transition metal complexes and inorganic semiconductors—have been prepared and immobilized on electrode surfaces to be used as sensitive and biocompatible probes for the detection of analytes. To date, they have successfully verified that ECL-based biosensors and bioassays have great potential for use in real-world applications. However, the development of highly-sensitive and biocompatible luminophores remains a long journey, and the practical conversion of ECL biosensors from basic research to real applications is still a major challenge. This Special Issue of Sensors will cover current research topics in the exciting field of ECL-based biosensors and bioassays, aiming at discovering how they are fabricated and what merits they have for specific bioanalytical applications.
We welcome submissions that are related to ECL biosensors, such as the development of new ECL luminophores, highly sensitive ECL detection methods potentially used as transduction platforms in biosensors and bioassays, and a wide range of new applications of ECL-based biosensors and bioassays. Both research papers and review articles will be considered. We look forward to and welcome your participation in this Special Issue.
Prof. Dr. Wonyong Lee
Guest Editor
Manuscript Submission Information
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Keywords
- Electrochemiluminescence (ECL)
- ECL biosensors
- ECL bioassays
- ECL immunosensors
- ECL sensors
- ECL detection platforms
