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Advances in Functional Nanocomposite Materials for Bioapplications

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Sensor Materials".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 3139

Special Issue Editors


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Guest Editor
Institute of Biomedical Materials, Zhejiang Sci-Tech University, Hangzhou 310018, China
Interests: biomaterials; nanoparticles; nano-composites; antibacterial applications; drug delivery
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Guest Editor
National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan
Interests: nanotechnology; nanomaterial fabrication; nanobiotechnology; bio/chemical sensing; electrochemical sensors; mass-sensitive devices; conductance-based sensors; lateral flow sensors; molecular imprinted polymer synthesis; metal-based nanocomposites; atomic force microscopy

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Guest Editor
Schulich School of Engineering, University of Calgary, Calgary, AB, Canada
Interests: organic nanomaterials; biomaterials; cancer photothermal and photodynamic therapies; cancer imaging; surface fluid detection

Special Issue Information

Dear Colleagues,

Nanomaterials have proven to be powerful tools in a wide range of biomedical and natural science applications. Various organic and inorganic nanocomposites with outstanding characteristics can be envisioned to revolutionize clinical diagnostics, real-time screening, drug delivery systems, and theranostics for life-threatening diseases. Advancements in synthesis tools and engineering can enable researchers to design innovative applications in tissue engineering, biosensing, diagnostics, nanomedicine, and therapeutics. An ideal nanocomposite system should be biocompatible, cost-effective, and entailing all the befits of chemical composition and morphology, with functional nanomaterials possessing outstanding properties as excellent substitutes for conventional approaches. For instance, the diagnostic modalities combined with therapeutic features demonstrate a promising platform for evaluating therapeutic interventions, and image-guided therapy techniques provide precise treatments to avoid unnecessary surgical procedures.

Researchers have paid much attention to developing advanced and highly biocompatible nanocomposites for the addressal and improvement of clinical and biomedical shortcomings in recent years, although a still challenging task is to combine multimodalities into a single platform with controlled dimensions favorable for practical bioapplications. This research theme is proposed to address new innovative synthesis protocols of functional nanomaterials, their structures, and functional relationship, as well as harness them to viable and state-of-the-art bioapplications.

The aim of this Special Issue, “Advances in Functional Nanocomposite Materials for Bioapplications” is to invite researchers and scholars to submit original research and review articles focusing on current developments, challenges, and solutions unleashing the potential of functional nanocomposites.

Potential research topics include, but are not limited to, the following:

  • Synthesis of functional biocompatible organic/inorganic nanocomposites;
  • Structure–property relationship of biocompatible nanocomposites;
  • Nanocomposites for antibacterial/wound dressing applications;
  • Nanocomposites for imaging-guided drug delivery;
  • Nanocomposite-based sensors for advanced screening or medical diagnostics;
  • Nanocomposites for microfluidics and wearable sensors;
  • Multifunctional biodegradable nanocomposites for tissue engineering;
  • Nanocomposite for therapeutic drug monitoring and in vivo imaging.

Prof. Dr. Muhammad Zubair Iqbal
Dr. Sadia Zafar Bajwa
Dr. Ozioma Akakuru
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanocomposites
  • hybrid nanomaterials
  • organic/inorganic nanocomposites
  • nanosensors
  • synergistic nanocomposites
  • imaging-guided therapy
  • biosensor
  • wearables

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Published Papers (2 papers)

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Research

14 pages, 3760 KiB  
Article
Synthesis of Multifunctional Mn3O4-Ag2S Janus Nanoparticles for Enhanced T1-Magnetic Resonance Imaging and Photo-Induced Tumor Therapy
by Yuguang Lu, Yuling Wu, Zhe Tang, Yike Hou, Mingyue Cui, Shuqi Huang, Binghua Long, Zhangsen Yu, Muhammad Zubair Iqbal and Xiangdong Kong
Sensors 2023, 23(21), 8930; https://doi.org/10.3390/s23218930 - 2 Nov 2023
Cited by 1 | Viewed by 1298
Abstract
The global burden of cancer is increasing rapidly, and nanomedicine offers promising prospects for enhancing the life expectancy of cancer patients. Janus nanoparticles (JNPs) have garnered considerable attention due to their asymmetric geometry, enabling multifunctionality in drug delivery and theranostics. However, achieving precise [...] Read more.
The global burden of cancer is increasing rapidly, and nanomedicine offers promising prospects for enhancing the life expectancy of cancer patients. Janus nanoparticles (JNPs) have garnered considerable attention due to their asymmetric geometry, enabling multifunctionality in drug delivery and theranostics. However, achieving precise control over the self-assembly of JNPs in solution at the nanoscale level poses significant challenges. Herein, a low-temperature reversed-phase microemulsion system was used to obtain homogenous Mn3O4-Ag2S JNPs, which showed significant potential in cancer theranostics. Structural characterization revealed that the Ag2S (5–10 nm) part was uniformly deposited on a specific surface of Mn3O4 to form a Mn3O4-Ag2S Janus morphology. Compared to the single-component Mn3O4 and Ag2S particles, the fabricated Mn3O4-Ag2S JNPs exhibited satisfactory biocompatibility and therapeutic performance. Novel diagnostic and therapeutic nanoplatforms can be guided using the magnetic component in JNPs, which is revealed as an excellent T1 contrast enhancement agent in magnetic resonance imaging (MRI) with multiple functions, such as photo-induced regulation of the tumor microenvironment via producing reactive oxygen species and second near-infrared region (NIR-II) photothermal excitation for in vitro tumor-killing effects. The prime antibacterial and promising theranostics results demonstrate the extensive potential of the designed photo-responsive Mn3O4-Ag2S JNPs for biomedical applications. Full article
(This article belongs to the Special Issue Advances in Functional Nanocomposite Materials for Bioapplications)
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11 pages, 5417 KiB  
Article
Design of Laboratory Stand for Displacement Measurement of IPMC Actuators
by Karina Koślik, Paweł Kowol, Rafał Brociek, Agata Wajda and Grazia Lo Sciuto
Sensors 2023, 23(3), 1271; https://doi.org/10.3390/s23031271 - 22 Jan 2023
Cited by 1 | Viewed by 1306
Abstract
The polymer technology based on Electroactive polymers and metal composite ionic polymer has great potential and advantages in many engineering fields. In this paper, a laboratory stand for testing Ionic polymer–metal composites (IPMC) is presented. The laboratory station includes a power supply system [...] Read more.
The polymer technology based on Electroactive polymers and metal composite ionic polymer has great potential and advantages in many engineering fields. In this paper, a laboratory stand for testing Ionic polymer–metal composites (IPMC) is presented. The laboratory station includes a power supply system and a measuring system for the displacement of IPMC composites. Tests and measurements are carried out using a laser transducer and a camera equipped with image analysis software to determine the IPMC strips displacement. The experimental investigation of IPMCs under different voltage supplies and waveforms, environmental working humidity conditions, temperature, and loading conditions has proved the significant influence of geometric dimension and the effect of increased stress on the displacement value. For materials powered by a higher voltage value, an increased deflection value was noted. In case of displacement, longer is the sample, higher is the displacement value. The length of the sample under load, affects adversely its performance, resulting in an increase in the load on the sample. For samples of a thick size, a more stable movement with and without load can be noticed. Full article
(This article belongs to the Special Issue Advances in Functional Nanocomposite Materials for Bioapplications)
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