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Advanced Optical Biosensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (1 August 2019) | Viewed by 4019

Special Issue Editor


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Guest Editor
Department of Photonics and Bioenginering, CEMDATIC, ETSI Telecomunicación, Universidad Politécnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain
Interests: photonics; materials science; sensors; nanotechnology
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Special Issue Information

Dear Colleagues,

Optical biosensors offer appealing advantages over other types of biosensing devices. These include non-invasive, safe, and multi-dimensional (i.e., intensity, wavelength, phase, polarization) interrogation, high spatial resolution, noise-free information channels, ease of achieving 2-D array testing, the availability of well-established technologies from communication industries (e.g., lasers of almost any wavelength, detector arrays, micro-/nano-machining, waveguides and high-speed links), and the coincidence of optical frequencies with a wide range of physical properties of bio-related materials in nature. Their potential application areas include healthcare (medical diagnostics), environmental monitoring, food and agriculture control, defense, and security.
This Special Issue welcomes both reviews and original research articles in the field of optical biosensors. Topics include, but are not restricted to, surface plasmon resonance (SPR) biosensors, SPR imaging, localized SPR, evanescent wave fluorescence biosensors, bioluminescent biosensors, optical waveguide interferometric biosensors, ellipsometric biosensors, reflectometric interference spectroscopy biosensors, surface-enhanced Raman scattering biosensors, metasurface-based biosensors, and biosensing optical platforms such as lab-on-a-chip and optical fiber sensing. Fluorescent labelling, bioreceptor immobilization procedures, and the integration of synthetic receptors such as molecularly imprinted polymers into optical transducers, as well as novel concepts in both label-based and label-free schemes, and applications of this type of biosensor are also of interest. We invite and encourage your participation in this Special Issue.

Prof. Carlos Angulo Barrios
Guest Editor

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Keywords

  • label-free optical biosensing
  • label-based optical biosensing
  • surface plasmon resonance
  • surface enhanced Raman spectroscopy
  • optical fiber sensor
  • optical waveguide
  • microelectromechanical systems
  • fluorescence biosensing
  • fluorescent labelling
  • optical interferometry
  • optical metasurfaces
  • lab on a chip
  • multiplexed detection
  • bioreceptor immobilization
  • synthetic receptors

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Published Papers (1 paper)

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Research

8 pages, 2932 KiB  
Article
Design of an Optical Probe to Monitor Vaginal Hemodynamics during Sexual Arousal
by Hyeryun Jeong, Myeongsu Seong, Hyun-Suk Lee, Kwangsung Park, Sucbei Moon and Jae Gwan Kim
Sensors 2019, 19(9), 2129; https://doi.org/10.3390/s19092129 - 8 May 2019
Cited by 3 | Viewed by 3598
Abstract
An optical probe was developed to measure the change of oxy-hemoglobin (OHb), deoxy- hemoglobin (RHb), and total hemoglobin (THb) along with temperature from the vaginal wall of female rats. Apomorphine (APO, 80 μg/kg) was administered to elicit sexual arousal in female Sprague Dawley [...] Read more.
An optical probe was developed to measure the change of oxy-hemoglobin (OHb), deoxy- hemoglobin (RHb), and total hemoglobin (THb) along with temperature from the vaginal wall of female rats. Apomorphine (APO, 80 μg/kg) was administered to elicit sexual arousal in female Sprague Dawley rats (SD, 180–200 g). The behavior changes caused by APO administration were checked before monitoring vaginal responses. The changes of oxy-, deoxy-, and total hemoglobin concentration and the temperature from the vaginal wall were monitored before, during, and after APO administration. Animals were under anesthesia during the measurement. After APO administration, the concentration of OHb (55 ± 29 μM/DPF), RHb (33 ± 25 μM/DPF), and THb (83 ± 59 μM/DPF) in the vaginal wall increased in a few min, while saline administration did not cause any significant change. In case of the vaginal temperature change, APO decreased the temperature slightly in the vaginal wall while saline administration did not show any temperature change in the vaginal wall. As the outcomes demonstrated, the developed probe can detect hemodynamic and temperature variation in the vaginal wall. The hemodynamic information acquired by the probe can be utilized to establish an objective and accurate standard of female sexual disorders. Full article
(This article belongs to the Special Issue Advanced Optical Biosensors)
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