Modulation of Host Cells and Tissues by Bacterial Toxins
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".
Deadline for manuscript submissions: closed (31 March 2023)
Special Issue Editors
Interests: bacterial toxins; genotoxicity; pathogenicity; enterobacteria
Special Issues, Collections and Topics in MDPI journals
Interests: bacterial toxins; epithelial cell pathogens; epithelial membrane receptors, cytoskeleton; intracellular trafficking of toxins; proinflammatory cytokines; bacterial secretion systems
Special Issue Information
Pathogenic bacteria secrete protein toxins and effectors (virulence factors) that modulate the physiological characteristics of host cells and tissues to create a more suitable niche for their colonization and, sometimes, to persist for extraordinary time periods. Bacterial toxins are feature that pathogenic bacteria have acquired to promote adaptation to the specific and often diverse environments found within the host. Bacterial toxins are not only killers, but the idea has also emerged that they perform more sophisticated functions during bacteria–host interactions by acting as negotiators. Depending on the toxin, its cellular target, affected physiological process and mode of action, the final regulatory outcome may be different. Therefore, it is also necessary to understand the multiple ways in which toxins contribute to a bacterial lifestyle that extends well beyond their ability to destroy host tissue. In this Special Issue, we are interested in investigations of the mechanisms of cellular entry and trafficking, as well as the action of toxins on diverse host cell and tissue processes, such as those which are offensive, defensive, or something else altogether. This includes adenylate cyclase-affecting toxins, surfactant-like toxins, protein-synthesis-inhibiting toxins, neurotoxins, superantigens, as well toxins affecting host cell membrane, cytoskeleton, cell cycle, programmed cell death, immune cells among others.
Prof. Dr. Eric Oswald
Prof. Dr. Fernando Navarro-Garcia
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- toxins
- effectors
- autotransporters
- immunomodulators
- toxin uptake
- toxin secretion and trafficking
- action mechanisms
- target proteins
- signaling pathways
- cell disruption
