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Toxins publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mechanisms Underlying Metabolic Regulation by Marine Toxins

edited by

Allan Cembella

submission deadline 31 Mar 2025 | Viewed by 361 | Submission Open

Keywords: chemical ecology; marine toxin; ecotoxicology; phycotoxins; marine bioactives; toxin biosynthesis; metabolic regulation; toxin mode of action; toxin modelling; metabolomics

(This special issue belongs to the Section Marine and Freshwater Toxins)

Alleviation of Mycotoxin-Induced Toxicity

edited by

Haifei Wang

and

Lvhui Sun

submission deadline 31 Mar 2025 | Viewed by 92 | Submission Open

Keywords: mycotoxin; plant extracts; small molecules; molecular targets; toxicity alleviation; molecular toxicology

(This special issue belongs to the Section Mycotoxins)

Biological Activities of Ribosome Inactivating Proteins II

edited by

José Miguel Ferreras

Lucía Citores

and

Rosario Iglesias

submission deadline 15 Apr 2025 | 5 articles | Viewed by 8641 | Submission Open

Keywords: antifeedant; antifungal; antitumoral; antiviral; apoptosis; immunotoxin; ribosome-inactivating protein (RIP); rRNA N-glycosylase

(This special issue belongs to the Section Plant Toxins)

New Aspects in Clinical Characteristics and Toxicology of Animal Venom

edited by

Marcos Hikari Toyama

submission deadline 15 Apr 2025 | 1 articles | Viewed by 1259 | Submission Open

Keywords: venomous animal; venom; envenoming; antivenom; drug; therapeutics; toxicology; pharmaceutical

(This special issue belongs to the Section Animal Venoms)

Neurotoxicity and Health Risks of Freshwater and Marine Toxin Exposure

edited by

Remedios Guzmán-Guillén

and

Leticia Diez-Quijada Jiménez

submission deadline 15 Apr 2025 | Viewed by 197 | Submission Open

Keywords: neurotoxicity; freshwater toxins; marine toxins; anatoxins; saxitoxins; BMAA; cylindrospermopsin; domoic acid; risk assessment; analytics

(This special issue belongs to the Section Marine and Freshwater Toxins)

Co-Occurrence of Mycotoxins and Their Combined Toxicity

edited by

Marzia Beccaccioli

submission deadline 25 Apr 2025 | Viewed by 96 | Submission Open

Keywords: mycotoxins; combined toxicity; analytical methods for simultaneous identification; (bio)control strategies; food safety; global warming; human and animal health

(This special issue belongs to the Section Mycotoxins)

Immunogenicity of Botulinum Toxin

edited by

Sara Samadzadeh

and

Harald Hefter

submission deadline 30 Apr 2025 | 9 articles | Viewed by 19062 | Submission Open

Keywords: botulinum neurotoxin (BoNT); botulinum neurotoxin type A (BoNT/A); neutralizing antibodies; immunoresistance; primary and secondary treatment failure; antigenicity; complex protein-free BoNT/A; complex protein containing BoNT/A; therapy switching

(This special issue belongs to the Section Bacterial Toxins)

Multi Methods for Detecting Natural Toxins

edited by Svetlana V. Malysheva

submission deadline 30 Apr 2025 | 6 articles | Viewed by 9621 | Submission Open

Keywords: fungal toxins; plant toxins; bacterial toxins; marine and freshwater toxins; method development; analysis; multi-toxin methods; validation

Eco-Toxins: Exploring Biological, Ecological and Environmental Impacts

edited by

Marco Masi

and

Antonietta Siciliano

submission deadline 30 Apr 2025 | Viewed by 326 | Submission Open

Keywords: toxins; chemical compositions; biological functionalities; ecological roles; environmental repercussions; interdisciplinary approach; chemistry; ecotoxicology; ecosystem dynamics; biodiversity

(This special issue belongs to the Section Marine and Freshwater Toxins)

Biomonitoring of Mycotoxins the Silent Invaders, Their Subtle Assault on Human and Animal Health

edited by

Cristina Juan García

and

Ana Juan-García

submission deadline 30 Apr 2025 | Viewed by 295 | Submission Open

Keywords: mycotoxins; biomonitoring; blood; cells; biotransformation; in vitro; in vivo; mass spectrometry

(This special issue belongs to the Section Mycotoxins)

Staphylococcus aureus Toxins Update: Detection, Prevention, and Response to Foodborne Outbreaks

edited by

Alexander Govaris

and

Andreana Pexara

submission deadline 30 Apr 2025 | Viewed by 130 | Submission Open

Keywords: Staphylococcus aureus; enterotoxins; foodborne toxicosis; food-borne disease; S. aureus toxins; TSST-1; outbreaks

(This special issue belongs to the Section Bacterial Toxins)

Snake Bite and Related Injury

edited by

Matteo Riccardo Di Nicola

submission deadline 15 May 2025 | Viewed by 85 | Submission Open

Keywords: snakebite; front-fanged snakes; Viperidae; Elapidae; Atractaspidae; non-front fanged; NFFC; epidemiology; veterinary toxicology

(This special issue belongs to the Section Animal Venoms)

Adverse Effects of Co-Contaminated Mycotoxins and Strategies for Their Mitigation

edited by

Wence Wang

submission deadline 20 May 2025 | Viewed by 80 | Submission Open

Keywords: co-contaminated mycotoxins; mechanisms of toxicity; mitigation strategies

(This special issue belongs to the Section Mycotoxins)

Advances in Mycotoxin Determination: From Risk Assessment to Global Management Strategies

edited by

Maykel Hernández-Mesa

submission deadline 20 May 2025 | Viewed by 79 | Submission Open

Keywords: mycotoxins; food analysis; exposure assessment; risk assessment; risk management

(This special issue belongs to the Section Mycotoxins)

Targeting Uremic Toxins in Chronic Kidney Disease: Novel Therapeutic Approaches

edited by

Christophe O. Soulage

, Fitsum Guebre-Egziabher and

Laetitia Koppe

submission deadline 21 May 2025 | Viewed by 92 | Submission Open

Keywords: uremic toxins; dialysis; hemodialysis; gut microbiota; prebiotics; probiotics; adsorbents; protein-bound uremic toxins

(This special issue belongs to the Section Uremic Toxins)

Transcriptomic and Proteomic Study on Animal Venom: Looking Forward

edited by Paulo Lee Ho

submission deadline 30 May 2025 | 2 articles | Viewed by 3138 | Submission Open

Keywords: transcriptome; proteome; venom composition; toxin(s)

(This special issue belongs to the Section Animal Venoms)

Biological and Pharmacological Properties of Botulinum Neurotoxins

edited by Zoltan Mari

submission deadline 30 May 2025 | Viewed by 264 | Submission Open

Keywords: botulinum neurotoxins; biochemical and physical properties; clinical applications

(This special issue belongs to the Section Bacterial Toxins)

Antibodies for Innovative Studies of Bacterial Toxins

edited by Roxane Maria Fontes Piazza and María M. Amaral

submission deadline 31 May 2025 | Viewed by 553 | Submission Open

Keywords: bacterial toxins; mechanism of action; antibodies; neutralization; detection; diagnosis; in vivo and in vitro models

(This special issue belongs to the Section Bacterial Toxins)

Analytical Novelties and Challenges for the Detection of Natural Toxins

edited by

Teresa D’Amore

and

Sofia Agriopoulou

submission deadline 31 May 2025 | Viewed by 380 | Submission Open

Keywords: analytical methods; detection and quantification; food & feed safety; risk assessment; surveillance; natural toxins; emerging toxins; mycotoxins; biotoxins; phytotoxins; immunoassays; mass spectrometry; chromatography; biosensors; green analytical chemistry

Current Status and Emerging Trends in the Biodiscovery of Canonical Toxins and Bioactive Peptides from Cnidarians

edited by

Dany Domínguez Pérez

Guillermin Agüero-Chapin

and Olga Castañeda

submission deadline 31 May 2025 | Viewed by 284 | Submission Open

Keywords: cnidarian toxins; bioactive peptides; toxin-like peptides; biodiscovery; OMICs; bioinformatics; evolutionary biology; genomics; transcriptomics; proteomics

(This special issue belongs to the Section Marine and Freshwater Toxins)

Important Value of Botulinum Toxin in Pain Management

edited by

Christian Wong

submission deadline 15 Jun 2025 | Viewed by 201 | Submission Open

Keywords: botulinum toxin; botulinum neurotoxin; neuropathic pain; neuralgia; pain medicine

(This special issue belongs to the Section Bacterial Toxins)

Pore-Forming Toxins: From Structure to Function

edited by

Peter A. Keyel

submission deadline 15 Jun 2025 | Viewed by 70 | Submission Open

Keywords: pore-forming toxin; cell signaling; hemolysin; host-pathogen interaction; cell death; cholesterol-dependent cytolysin; plasma membrane; toxin evolution

(This special issue belongs to the Section Bacterial Toxins)

The Evolving Role of Botulinum Toxin in Clinical Therapeutics

edited by

Barbara Karp

and Zoltan Mari

submission deadline 15 Jun 2025 | Viewed by 11 | Submission Open

Keywords: botulinum toxin; therapeutics; dystonia; spasticity; aesthetics; pain; migraine; headache; achalasia; sphincter dysfunction; strabismus; hyperhidrosis; hemifacial spasm; tics

(This special issue belongs to the Section Bacterial Toxins)

The Role of Uremic Toxins in Comorbidities of Chronic Kidney Disease

edited by Suguru Yamamoto

submission deadline 20 Jun 2025 | Viewed by 54 | Submission Open

Keywords: uremic toxins; chronic kidney disease; hemodialysis; blood purification; frailty; mortality; cardiovascular; fracture; infection; pruritus; cognitive disorder

(This special issue belongs to the Section Uremic Toxins)

Advances in Contamination, Detection and Risk Assessment of Mycotoxins

edited by José Diana Di Mavungu

submission deadline 25 Jun 2025 | 3 articles | Viewed by 4001 | Submission Open

Keywords: mycotoxins; detection methods; occurrence; contamination; exposure assessment; risk assessment; recent developments and applications; new challenges and trends

(This special issue belongs to the Section Mycotoxins)

Botulinum Toxins: New Uses in the Treatment of Diseases (2nd Edition)

edited by

Siro Luvisetto

submission deadline 30 Jun 2025 | 4 articles | Viewed by 3352 | Submission Open

Keywords: botulinum toxin; animal models; human diseases; clinical study; case reports; off-label use; new indications

(This special issue belongs to the Section Bacterial Toxins)

Animal Venoms: Unraveling the Molecular Complexity (2nd Edition)

edited by

Ren Lai

and

Qiumin Lu

submission deadline 30 Jun 2025 | 3 articles | Viewed by 2747 | Submission Open

Keywords: venomous animal; venom; toxin; protein; peptide; receptor; ion channel; transcriptomics; proteomics; bioinformatics

(This special issue belongs to the Section Animal Venoms)

Plant Toxin Emergency

edited by

Andrea Bolognesi

and

Massimo Bortolotti

submission deadline 30 Jun 2025 | Viewed by 104 | Submission Open

Keywords: plant toxins; secondary metabolites; alkaloids; ribosome-inactivating proteins; toxic lectins; biological activity; toxicity mechanisms; clinical features of intoxication; bioterrorism; toxin detection

(This special issue belongs to the Section Plant Toxins)

Special Issue in Honor of Prof. Richard J. Lewis: “From Ciguatera to Conotoxin Research”

edited by