Pathogenesis of Viral Infections

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 32

Special Issue Editor


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Guest Editor
Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 404, Taiwan
Interests: viral pathogenesis; antiviral agents; viral diagnosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Viral infections remain a major challenge to global health, affecting multiple physiological systems and leading to severe complications. Understanding their pathogenesis is essential for developing effective treatments and preventive strategies. Both human and zoonotic viruses, such as influenza and SARS-CoV-2, demonstrate the complexity of these infections, impacting specific systems while causing widespread effects in other organs. Complications like pneumonia, respiratory failure, and long-term sequelae highlight the importance of gaining deeper insights into viral mechanisms. Investigating the pathways of viral pathogenesis offers valuable insights into how viruses interact with the host, trigger immune responses, and contribute to prolonged health impacts. The immune response, particularly the activation of the NLRP3 inflammasome, plays a critical role in both protecting the host and exacerbating disease severity. This issue will explore the molecular mechanisms behind human and zoonotic viral diseases, with a focus on systems-level analyses of viral pathogenesis, immune regulation, and emerging therapeutic strategies aimed at mitigating viral-induced damage. Through this research, we aim to enhance the understanding of viral infection pathogenesis and its broader implications for human health.

Prof. Dr. Cheng-Wen Lin
Guest Editor

Manuscript Submission Information

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Keywords

  • human and zoonotic viral diseases
  • viral pathogenesis
  • systems-level analyses
  • immune response
  • protein–protein interactions

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Published Papers

This special issue is now open for submission.
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