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Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research and Clinical Application of Adenovirus (AdV), 3rd Edition

edited by

Julia Davydova

submission deadline 25 May 2025 | 1 articles | Viewed by 1534 | Submission Open

Keywords: adenovirus; gene therapy; cancer; oncolytic; vaccine; delivery

(This special issue belongs to the Section Human Virology and Viral Diseases)

Influenza, SARS-CoV-2, RSV and Other Vaccines: Immunogenicity Parameters and Protection, 3rd Edition

edited by

Zoltan Vajo

submission deadline 30 May 2025 | 7 articles | Viewed by 13470 | Submission Open

Keywords: SARS-CoV-2; serology; cellular immune response; protection; vaccines; influenza; Respiratory Syncytial Virus (RSV)

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Emerging Microbes, Infections and Spillovers, 2nd Edition

edited by

Ravi Kant

Tarja Sironen

and

Maciej Grzybek

submission deadline 30 May 2025 | 1 articles | Viewed by 829 | Submission Open

Keywords: emerging infections; virus spillovers; microbes; cross-species transmission; virus evolution; viral disease; virus reservoirs; virus– host interaction; pathogenesis

(This special issue belongs to the Section Animal Viruses)

Endogenous Retrovirus Proteins and Their Functions, 2nd Edition

edited by

Benoit Barbeau

submission deadline 30 May 2025 | Viewed by 381 | Submission Open

Keywords: endogenous retrovirus; ERV envelope protein; receptor; cell fusion; cancer; pre-eclampsia; obstetric disorder; diagnosis; evolutionary conservation; gene regulation

(This special issue belongs to the Section Human Virology and Viral Diseases)

Chronic Infection by Oncogenic Viruses

edited by

Christophe Nicot

submission deadline 31 May 2025 | 6 articles | Viewed by 16886 | Submission Open

Keywords: virus transmission; virus replication; virus pathogenesis; virus latency; virus– host interactions; antiviral immune responses; virus-induced cellular transformation; antiviral drugs and vaccines

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Microscopy Methods for Virus Research

edited by Krishanu Ray

submission deadline 31 May 2025 | 5 articles | Viewed by 14558 | Submission Open

Keywords: viruses; fluorescence imaging; single-molecule imaging; super-resolution imaging; intra-vital imaging; electron microscopy; Cryo-EM; Cryo-ET

(This special issue belongs to the Section General Virology)

Functional and Structural Features of Viral RNA Elements

edited by

Stefan Weger

submission deadline 31 May 2025 | 4 articles | Viewed by 9680 | Submission Open

Keywords: RNA viruses; IRES elements; cap-independent protein synthesis; translation initiation; conserved RNA motifs

(This special issue belongs to the Section General Virology)

Human T-Cell Leukemia Virus (HTLV) Infection and Treatment

edited by Cynthia A. Pise-Masison and Damian F.J. Purcell

submission deadline 31 May 2025 | 5 articles | Viewed by 8487 | Submission Open

Keywords: HTLV; HTLV-associated myelopathy/tropical spastic paraparesis; adult T-cell leukemia/lymphoma; inflammation; neurodegeneration; therapeutics; infectious dermatitis; cancer; antiviral drugs

(This special issue belongs to the Section Human Virology and Viral Diseases)

Avian Respiratory Viruses, 4th Edition

edited by

Faizal Careem

submission deadline 31 May 2025 | 3 articles | Viewed by 6307 | Submission Open

Keywords: avian influenza virus; newcastle disease virus; infectious bronchitis virus; infectious laryngotracheitis; virus evolution; pathogenesis; virus– host interaction; vaccine; innate immune response; adjuvant; avian; avian metapneumovirus (aMPV)

(This special issue belongs to the Section Animal Viruses)

Within-Host Viral Dynamics: A Window into Viral Evolution

edited by

Xiaofeng Fan

and

Mahmoud Reza Pourkarim

submission deadline 31 May 2025 | 2 articles | Viewed by 6038 | Submission Open

Keywords: virome; metagenomics; phylogenetics; viral evolution; quasispecies; infectious diseases

(This special issue belongs to the Section General Virology)

TMPRSS2 in Influenza Virus and Coronavirus Infections

edited by

Judy Wai Ping Yam

and Sze Keong Tey

submission deadline 31 May 2025 | 2 articles | Viewed by 4782 | Submission Open

Keywords: TMPRSS2; influenza virus; coronavirus; viral infection; treatment of viral diseases

(This special issue belongs to the Section Human Virology and Viral Diseases)

Measles, Mumps, and Rubella

edited by Alberto Severini

submission deadline 31 May 2025 | 2 articles | Viewed by 3707 | Submission Open

Keywords: measles; mumps; rubella; molecular epidemiology; next generation sequencing; analysis of outbreaks; vaccine preventable diseases

(This special issue belongs to the Section Human Virology and Viral Diseases)

Tick-Borne Viruses: Transmission and Surveillance, 2nd Edition

edited by

Anna Papa

submission deadline 31 May 2025 | 1 articles | Viewed by 3099 | Submission Open

Keywords: tick-borne viruses; transmissibility; vector competence; virulence; interactions; surveillance; discovery; replication; pathogenesis; vaccine development

(This special issue belongs to the Section Invertebrate Viruses)

Virus Recombination

edited by

Alexandre Hassanin

submission deadline 31 May 2025 | 1 articles | Viewed by 1915 | Submission Open

Keywords: RNA viruses; DNA viruses; inter-genomic recombination; recombination rates; virus diversity; host ranges; methods of detection; models of recombination

(This special issue belongs to the Section General Virology)

Role of Lectins in Viral Infections and Antiviral Intervention

edited by Yuan Guo

submission deadline 31 May 2025 | 1 articles | Viewed by 1383 | Submission Open

Keywords: lectin– glycan interaction; membrane fusion; immune evasion; multivalency; glycan conjugates; lectin constructs; antivirals

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Severe Fever with Thrombocytopenia Syndrome Virus 2025

edited by

Masayuki Saijo

submission deadline 31 May 2025 | 1 articles | Viewed by 708 | Submission Open

Keywords: SFTS; SFTSV; emerging viral infections

(This special issue belongs to the Section Human Virology and Viral Diseases)

Novel Insights into Porcine Viral Diseases: Recombinant Strains and Immune Responses

edited by

Kegong Tian

and

Xiangdong Li

submission deadline 31 May 2025 | 1 articles | Viewed by 575 | Submission Open

Keywords: porcine viral diseases; epidemiology; pathogenesis; recombination; immune responses

(This special issue belongs to the Section Animal Viruses)

Pharmacology of HIV Treatment and Antivirals Against Hepatitis Viruses

edited by José Vicente Fernández-Montero

submission deadline 31 May 2025 | Viewed by 332 | Submission Open

Keywords: long-acting injectable antiretrovirals; broadly neutralizing antibodies; direct-acting antivirals; entry inhibitors; drug administration; HIV-2; HTLV; antiviral drugs; HIV and viral hepatitis vaccines

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Chronic Wasting Disease: From Pathogenesis to Prevention

edited by Jiewen Guan and Hongsheng Huang

submission deadline 31 May 2025 | Viewed by 316 | Submission Open

Keywords: prion disease; pathogenesis; host genetics and disease resistance; disease transmission; detection and diagnosis; epidemiology; prevention

(This special issue belongs to the Section Prions)

RNA Viruses Replication and Innate Immunity

edited by

Griffith Parks

submission deadline 31 May 2025 | Viewed by 251 | Submission Open

Keywords: RNA virus replication and transcription; pathogen-associated molecular patterns; interferons; cytokines; signaling pathways

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Bornaviruses 2025: News, Gaps and Future Directions

edited by

Christiane E. Herden

submission deadline 31 May 2025 | Viewed by 166 | Submission Open

Keywords: bornaviruses; zoonotic; epidemiology; transmission; molecular infection mechanisms; pathogenesis; antiviral

(This special issue belongs to the Section Animal Viruses)

Discovery, Classification, and Early Research on the Lipid-Containing, Double-Stranded RNA Bacteriophage φ6

edited by

Paul Gottlieb

and Aleksandra Alimova

submission deadline 15 Jun 2025 | 7 articles | Viewed by 18440 | Submission Open

Keywords: procapsid; nucleocapsid; polymerase complex; assembly; replication; recombination; packaging10

(This special issue belongs to the Section Bacterial Viruses)

Long-Acting Antiretrovirals

edited by Camilla Muccini and Antonella Castagna

submission deadline 15 Jun 2025 | Viewed by 181 | Submission Open

Keywords: HIV infection; HIV prevention; long-acting; antiretroviral therapy; clinical studies

(This special issue belongs to the Section Human Virology and Viral Diseases)

Recent Advances on Arboviruses Pathogenesis and Evolution

edited by Mariana Sequetin Cunha

submission deadline 17 Jun 2025 | 2 articles | Viewed by 1485 | Submission Open

Keywords: virus outbreaks; phylogeny; virus evolution; pathology

(This special issue belongs to the Section Invertebrate Viruses)

Bacteriophage Lytic Proteins

edited by

Madalena Pimentel

submission deadline 20 Jun 2025 | 3 articles | Viewed by 5610 | Submission Open

Keywords: bacteriophage; phage lysis; holins; endolysins; spanins; mycolil esterases; antimicrobials

(This special issue belongs to the Section Bacterial Viruses)

Dengue, Zika and Yellow Fever Virus Replication

edited by

Rosa M. Del Angel

submission deadline 25 Jun 2025 | Viewed by 367 | Submission Open

Keywords: flavivirus; dengue; Zika; yellow fever; virus replication; virus entry; genome replication; host cell factors; replication structures

(This special issue belongs to the Section Invertebrate Viruses)

Canine Distemper Virus

edited by Monica G. Candela and

Nieves Ortega Hernández

submission deadline 30 Jun 2025 | 7 articles | Viewed by 11341 | Submission Open

Keywords: CDV taxonomy (lineages); new hosts of CDV; CDV pathogenesis; CDV epidemiology (risk factors; distribution; and prevalence); CDV prevention/risk mitigation

(This special issue belongs to the Section Animal Viruses)

Controlling Zoonotic Viral Diseases from One Health Perspective 2025

edited by

Maureen T. Long

and Erika Schwarz-Collins

submission deadline 30 Jun 2025 | 4 articles | Viewed by 9802 | Submission Open

Keywords: one health; viral zoonoses; control; vaccine; surveillance; epidemiology

(This special issue belongs to the Section Animal Viruses)

Viral Sepsis: Pathogenesis, Diagnostics and Therapeutics

edited by

Karolina Akinosoglou

and

Charalambos Gogos

submission deadline 30 Jun 2025 | 6 articles | Viewed by 9748 | Submission Open

Keywords: viral sepsis; HIV; HBV; HCV; EBV; HDV; HEV; CMV; HSV; HPV; influenza; RSV; COVID-19; SARS-CoV-2; other viruses; viral infection; sepsis; pathogenesis; diagnosis; therapy; biomarkers; vaccination

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Vertical Transmission of Human Papillomavirus Infections

edited by

Stina Syrjänen

submission deadline 30 Jun 2025 | 3 articles | Viewed by 9448 | Submission Open

(This special issue belongs to the Section Animal Viruses)

Cellular Restriction Factors against Viral Infection

edited by

Stephen Barr

submission deadline 30 Jun 2025 | 2 articles | Viewed by 9334 | Submission Open

Keywords: cellular restriction factors; antiviral proteins; viral antagonists; intrinsic immunity; interferon response; innate immunity; evolution of restriction factors; evolution of viral antagonists; viral antagonists as druggable targets

(This special issue belongs to the Section General Virology)

Advances in Alphavirus and Flavivirus Research, 2nd Edition

edited by

Young Chan Kim

and

Arturo Reyes-Sandoval

submission deadline 30 Jun 2025 | 9 articles | Viewed by 9066 | Submission Open

Keywords: arbovirus; alphavirus; flavivirus; Chikungunya; Mayaro; Zika; dengue; diagnostics; surveillance; vaccine; antivirals; animal models

(This special issue belongs to the Section General Virology)

Immune Modulation by Human Cytomegalovirus

edited by

Davide Abate

submission deadline 30 Jun 2025 | 6 articles | Viewed by 8495 | Submission Open

Keywords: human cytomegalovirus (CMV); molecular and cellular mechanisms; cell-intrinsic immunity; adaptive immunity; innate immunity

(This special issue belongs to the Section Human Virology and Viral Diseases)

Viral Hepatitis and Liver Diseases

edited by

Carlo Smirne

submission deadline 30 Jun 2025 | 7 articles | Viewed by 7564 | Submission Open

Keywords: chronic viral infection; viral hepatitis; liver fibrosis; hepatocellular carcinoma; hepatitis B virus; hepatitis C virus; hepatitis delta virus co-infection; hepatitis E virus; flavivirus; molecular mechanisms; epidemiological investigations

(This special issue belongs to the Section Human Virology and Viral Diseases)

Coronaviruses and Influenza Viruses: Evolution, Cross-Species Transmission, and Recombination

edited by

Maged Gomaa Hemida

submission deadline 30 Jun 2025 | 4 articles | Viewed by 4564 | Submission Open

Keywords: coronaviruses; influenza viruses; highly pathogenic influenza viruses; species jump; avian coronaviruses; porcine coronaviruses; vaccines; diagnostic assays; one health; virus/host interaction.

(This special issue belongs to the Section Coronaviruses)

Diversity and Coinfections of Plant or Fungal Viruses, 3rd Edition

edited by

Islam Hamim

Ken Komatsu

and

Hiromitsu Moriyama

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4514 | Submission Open

Keywords: diagnosis; surveillance; molecular mechanism; viroid; subviral agents; mycoviruses; biological control; pesticide resistance; antiviral defense mechanism; population genetics; recombination; gene expressions; host range

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Plant Virus Spillovers

edited by

Steve Wylie

and

Nuredin Habili

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4446 | Submission Open

Keywords: spillover; emergence; replication; wild-plant virus; transmission; virus-cell interaction; vector

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Viruses and Eye Diseases

edited by Homayon Ghiasi and

Deepak Shukla

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4061 | Submission Open

Keywords: ocular health; herpesviruses; herpes simplex virus (HSV); varicella zoster virus (VZV); adenovirus; respiratory viruses; Zika virus; cytomegalovirus (CMV); virus– ocular tissue interactions

(This special issue belongs to the Section Human Virology and Viral Diseases)

Biotechnological Applications of Phage and Phage-Derived Proteins 2025

edited by

Silvio Santos

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3466 | Submission Open

Keywords: bacteriophage; biotechnological applications; genetic engineering; antimicrobials; diagnostic

(This special issue belongs to the Section Bacterial Viruses)

Interplay Between Influenza Virus and Host Factors

edited by

Matloob Husain

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3236 | Submission Open

Keywords: influenza virus; host factors; proviral host factors; antiviral host factors; host adaptation; virus entry; virus assembly; virus release; innate antiviral response; interferon-stimulated genes; post-translational protein modifications

(This special issue belongs to the Section Animal Viruses)

Zoonotic Viral Diseases: Drivers, Causes, Prevention and Cure, 2nd Edition

edited by

Claude Saegerman

submission deadline 30 Jun 2025 | 4 articles | Viewed by 2729 | Submission Open

Keywords: zoonotic viral diseases; drivers of emergence; disease mechanism and pathogenesis in reservoir host and end host; prevention mitigation measures; treatment

(This special issue belongs to the Section Animal Viruses)

Molecular Virus-Insect Interactions, 2nd Edition

edited by Li-Long Pan

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2707 | Submission Open

Keywords: plant virus-insect vector interactions; virus transmission; entomopathogenic virus-insect host interactions; insect-specific viruses; induction and suppression of immune responses

(This special issue belongs to the Section Invertebrate Viruses)

HIV Protease

edited by

Gail E. Fanucci

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2133 | Submission Open

Keywords: HIV protease; antiretroviral therapy; drug resistance; inhibitor development; viral maturation; viral co-evolution; natural polymorphism

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Virological and Immunological Factors Underlying HBV Functional Cure and HBV Reactivation

edited by

Valentina Svicher

submission deadline 30 Jun 2025 | Viewed by 538 | Submission Open

Keywords: HBV persistence; HBV functional cure; cccDNA; immunology of HBV; HBV reactivation; immune-escape mutations

(This special issue belongs to the Section Human Virology and Viral Diseases)

Viral Manipulation of Plant Stress Responses

edited by

Miguel A. Aranda

and Manuel Miras

submission deadline 30 Jun 2025 | Viewed by 457 | Submission Open

Keywords: virus– plant interactions; virus– host– vector interactions; immune responses; hormone signaling; evolutionary adaptations; crop protection; stress responses

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Viral Infection and Platelets’ Disorders

edited by

Pierpaolo Di Micco

Alessandro Perrella

and

Giuseppe Camporese

submission deadline 30 Jun 2025 | Viewed by 321 | Submission Open

Keywords: viral infections; thrombosis; thrombotic microangiopathies; disseminated intravascular coagulation; low molecular weight heparin; bleedings; acute infections

(This special issue belongs to the Section Human Virology and Viral Diseases)

Advancing Research of Anelloviruses, Second Edition

edited by

Fabrizio Maggi

and

Pietro Giorgio Spezia

submission deadline 30 Jun 2025 | Viewed by 316 | Submission Open

Keywords: TTV; TTMV; TTMDV; virome; viral species; immune system; orphan virus

(This special issue belongs to the Section Human Virology and Viral Diseases)

Interferon Signaling in Viral Pathogenesis

edited by Lishan Su

submission deadline 30 Jun 2025 | Viewed by 273 | Submission Open

Keywords: type I interferons; virus replication; viral pathogenesis; autoimmune diseases; inflamation-induced cancer; immunotherapy

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Bacteriophage Diversity, 2nd Edition

edited by Bert Ely

submission deadline 30 Jun 2025 | Viewed by 128 | Submission Open

Keywords: bacteriophages phage; diversity genome; evolution; new genera; phage-host interactions

(This special issue belongs to the Section Bacterial Viruses)

Epigenetic Modifications in Viral Infections, Volume II

edited by

Matloob Husain

and

Farjana Ahmed

submission deadline 1 Jul 2025 | Viewed by 332 | Submission Open

Keywords: viral pathogenesis; virus– host interaction; epigenetic modifications; acetylation; methylation; proteomics; genomics

(This special issue belongs to the Section General Virology)

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