Phage Display in Cancer Diagnosis and Screening
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Bacterial Viruses".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 25
Special Issue Editor
Interests: phage display and phage nanobiotechnology; targeted drug and gene delivery; cancer nanomedicines; diagnosis of infectious diseases and cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Early cancer diagnosis is highly beneficial for the survival of cancer patients. Therefore, there is an urgent need for screening tools for the identification of early signs of cancer pathologies before symptoms appear. Despite recent progress in early diagnosis using liquid biopsy technologies, the early blood-based detection of breast, lung, colorectal, and other cancers is still a challenge. In this respect, the “Holy Grail” for cancer researchers and bioengineers for decades has been the use of molecular sensing probes, which would allow for the screening, diagnosis, prognosis, and monitoring of cancer diseases by their highly specific interactions with cancer cellular antigens and overexpressed blood biomarkers. To date, most analytical platforms for the detection of cancer biomarkers use monoclonal antibodies (mAb) as targeting and sensing probes. However, because of their high cost, background binding, and technological and storage hardships, the application of mAb as an analytical standard is limited. This Special Issue aims to demonstrate the power of phage display as a universal tool for directed molecular evolution in cancer research. We call for manuscripts that explore the fundamental principles of phage display and molecular evolution in novel ways in the development of diagnostics for cancer diseases.
Prof. Dr. Valery A. Petrenko
Guest Editor
Manuscript Submission Information
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Keywords
- phage display
- cancer
- diagnosis
- screening
- prognosis and monitoring
