Influenza B Virus: From Infection to Prevention
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".
Deadline for manuscript submissions: 30 May 2025 | Viewed by 89
Special Issue Editor
Interests: influenza drug susceptibility monitoring; virus fitness; preclinical models for infection; antiviral development
Special Issue Information
Dear Colleagues,
Influenza A (IAV) and B (IBV) viruses co-circulate yearly during seasonal epidemics. IBV causes about a quarter of all influenza cases in an average season. Both influenza types cause severe respiratory illnesses in humans. IAV significantly affects young children and the elderly, while the burden of IBV infections is especially high among school-aged children in terms of incidence, hospitalization, and fatal outcomes, with the underlying pathogenic mechanisms remaining unclear. The primary treatment for influenza, Neuraminidase inhibitors (NAIs), are less effective against IBV compared to IAV. In the 21st century, two lineages of IBV, B/Victoria and B/Yamagata, have been co-circulating. After non-pharmaceutical interventions that were introduced during the COVID-19 pandemic, B/Yamagata lineage viruses have not been detected. Less research has been conducted on IBV than on IAV, as IBV lacks an established animal reservoir and pandemic potential. However, this also means that IBV infections and transmissions could be controlled well by broadly protective vaccines.
The objective of this Special Issue is to collect articles (research articles, short communications, reviews, and commentaries) that focus on surveillance, advancing knowledge about IBV epidemiology, evolution, antigenicity, pathogenesis, and immunity, as well as suitable animal models for infection, which is critical for the development of seasonal influenza vaccines and novel treatment strategies.
Dr. Saira Hussain
Guest Editor
Manuscript Submission Information
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Keywords
- influenza B viruses
- epidemiology
- evolution
- pathogenesis
- immunity
- vaccine
- antivirals
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