The Role of Dendritic Cells and Macrophages in HIV Infection
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: 15 November 2024 | Viewed by 137
Special Issue Editors
Interests: dendritic cells; HIV; antigen processing and presentation
Interests: mucosal immunity; HIV-1; SARS-CoV-2
Interests: mucosal immunity; HIV-1; HSV
Special Issue Information
Dear Colleagues,
The role of dendritic cells and macrophages in HIV infection should be frequently re-evaluated, as it evolves constantly. As the first cells with HIV receptors and co-receptors encountered by the virus at contamination sites, dendritic cells and macrophages are reservoirs and can transfer the virus to CD4+ T cells and activate them for full-blown replication. As innate immune cells, they detect the virus and initiate intrinsic, innate, and adaptive immune responses. They are major sources of interferons and other antiviral cytokines and can be cytotoxic. As antigen-presenting cells, they are necessary for constant adaptation to viral escape from T- and B-cell responses, and they are targeted or sometimes used by themselves for vaccination. During chronic, antiretroviral-treated infection, their constant activation is a source of metabolic complications and comorbidities. Understanding how to use their properties to achieve immune control over HIV-1 is key to obtaining a functional cure for HIV and removing the necessity for life-long antiretroviral treatments.
We are pleased to invite you to participate in a Special Issue of Viruses on “The Role of Dendritic Cells and Macrophages in HIV Infection”. Research areas may include (but are not limited to) defining the roles of new populations of dendritic cells and macrophages or monocytes in HIV infection, their cross-talk with other cell populations, their roles as reservoirs, strategies to stimulate them in order to eliminate HIV reservoirs and boost innate and adaptive immunity, and any other new, exciting results that you would like to share or discuss.
Original research articles and reviews are welcome.
Dr. Anne Hosmalin
Dr. Morgane Bomsel
Prof. Anthony Cunningham
Prof. Dr. Petronela Ancuta
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- reservoirs
- viral control
- vaccination
- cell interactions
- interferons
- cytokines
- mucosa
- lymphoid organs
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