Idiopathic Osteoporosis and Nephrolithiasis: Two Sides of the Same Coin?
Abstract
:1. Introduction
2. Definition and Epidemiological Data
3. Natural History and Statistical Evidence
4. Pathogenesis
4.1. Modifiable Risk Factors
4.2. Non-Modifiable Risk Factors
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Gene | HGNC Symbol | Location | Ref. |
---|---|---|---|
Calcium-sensing receptor | CASR | 3q13.3-q21.1 | [124,125,126] |
Vitamin D receptor | VDR | 12q13.11 | [127,128,129,130,131,132] |
Alkaline phosphatase | ALPL | 1p36.12 | [133,134] |
Osteopontin | SPP1 | 4q22.1 | [135,136] |
Claudin 14 | CLDN14 | 21q22.13 | [137,138,139] |
Type 2a sodium–phosphate cotransporter | SLC34A1 | 5q35.3 | [140] |
Fibroblast growth factor 23 | FGF23 | 12p13.32 | [141] |
25(OH)D-24-hydroxylase | CYP24A1 | 20q13.2 | [142] |
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Rendina, D.; De Filippo, G.; Iannuzzo, G.; Abate, V.; Strazzullo, P.; Falchetti, A. Idiopathic Osteoporosis and Nephrolithiasis: Two Sides of the Same Coin? Int. J. Mol. Sci. 2020, 21, 8183. https://doi.org/10.3390/ijms21218183
Rendina D, De Filippo G, Iannuzzo G, Abate V, Strazzullo P, Falchetti A. Idiopathic Osteoporosis and Nephrolithiasis: Two Sides of the Same Coin? International Journal of Molecular Sciences. 2020; 21(21):8183. https://doi.org/10.3390/ijms21218183
Chicago/Turabian StyleRendina, Domenico, Gianpaolo De Filippo, Gabriella Iannuzzo, Veronica Abate, Pasquale Strazzullo, and Alberto Falchetti. 2020. "Idiopathic Osteoporosis and Nephrolithiasis: Two Sides of the Same Coin?" International Journal of Molecular Sciences 21, no. 21: 8183. https://doi.org/10.3390/ijms21218183