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Review

“Lessons Learned” Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review

1
Geisinger NeuroScience Institute, Geisinger Health System, Danville, PA 17822, USA
2
Yale New Haven Hospital, Department of Neurology, New Haven, CT 06510, USA
3
Department of Population Health Sciences, Geisinger Health System, Danville, PA 17822, USA
4
Department of Molecular and Functional Genomics, Geisinger Health System, Danville, PA 17822, USA
5
Department of Public Health Sciences, College of Medicine, The Pennsylvania State University, Hershey, PA 16802, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2021, 10(18), 4209; https://doi.org/10.3390/jcm10184209
Submission received: 11 July 2021 / Revised: 9 September 2021 / Accepted: 10 September 2021 / Published: 17 September 2021
(This article belongs to the Section Vascular Medicine)

Abstract

Recurrent ischemic strokes are a cause of significant healthcare burdens globally. Patients with uncontrolled vascular risk factors are more likely to develop recurrent ischemic strokes. This study aims to compile information gained from current secondary prevention programs. A pre-defined literature search strategy was applied to PubMed, SCOPUS, CINAHL, and Google Scholar databases, and studies from 1997 to 2020 were evaluated for quality, study aims, and outcomes. The search produced 1175 articles (1092 after duplicates were removed) and titles were screened; 55 titles were retained for the full-text analysis. Of the remaining studies, 31 were retained for assessment, five demonstrated long-term effectiveness, eight demonstrated short-term effectiveness, and 18 demonstrated no effectiveness. The successful studies utilized a variety of different techniques in the categories of physical fitness, education, and adherence to care plans to reduce the risk of recurrent strokes. The lessons we learned from the current prevention programs included (1) offer tailored care for underserved groups, (2) control blood pressure, (3) provide opportunities for medication dosage titration, (4) establish the care plan prior to discharge, (5) invest in supervised exercise programs, (6) remove barriers to accessing care in low resource settings, and (7) improve the transition of care.
Keywords: recurrent stroke; secondary prevention; cerebrovascular disease recurrent stroke; secondary prevention; cerebrovascular disease

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MDPI and ACS Style

Lambert, C.M.; Olulana, O.; Bailey-Davis, L.; Abedi, V.; Zand, R. “Lessons Learned” Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review. J. Clin. Med. 2021, 10, 4209. https://doi.org/10.3390/jcm10184209

AMA Style

Lambert CM, Olulana O, Bailey-Davis L, Abedi V, Zand R. “Lessons Learned” Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review. Journal of Clinical Medicine. 2021; 10(18):4209. https://doi.org/10.3390/jcm10184209

Chicago/Turabian Style

Lambert, Clare McGarvey, Oluwaseyi Olulana, Lisa Bailey-Davis, Vida Abedi, and Ramin Zand. 2021. "“Lessons Learned” Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review" Journal of Clinical Medicine 10, no. 18: 4209. https://doi.org/10.3390/jcm10184209

APA Style

Lambert, C. M., Olulana, O., Bailey-Davis, L., Abedi, V., & Zand, R. (2021). “Lessons Learned” Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review. Journal of Clinical Medicine, 10(18), 4209. https://doi.org/10.3390/jcm10184209

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