Does Antrum Size Matter in Sleeve Gastrectomy? Volume II—A Retrospective Multicentric Study with Long-Term Follow-Up
Abstract
:1. Introduction
2. Methods
2.1. Study Setting and Study Population
2.2. GERD Health-Related Quality of Life (HRQL)
2.3. Surgical Technique
2.4. Outcome Measures
2.5. Study Outcomes
2.6. Statistical Analysis
3. Results
3.1. Study Population
3.2. Primary Outcome
3.3. Secondary Outcome
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Group A (241 pts) | Group B (356 pts) | p | |
---|---|---|---|
Age (years) * | 37.1 ± 6.7 | 36.8 ± 7.9 | 0.149 |
Gender (female/male) | 131/110 | 184/172 | 0.521 |
Weight (kg) * | 135.7 ± 11.4 | 134.4 ± 9.5 | 0.489 |
BMI (kg/m2) * | 45.1 ± 3.8 | 44.3 ± 9.8 | 0.612 |
ASA (I–II) (%) | 180 (74.6%) | 273 (76.7%) | 0.575 |
ASA (III–IV) (%) | 61 (25.4%) | 83 (23.3%) | 0.575 |
T2MD (%) | 31 (12.8%) | 42 (11.8%) | 0.696 |
COPD (%) | 6 (2.5%) | 9 (2.5%) | 0.976 |
Heart ischemia (%) | 0 | 1 (0.2%) | 0.411 |
Hypertension (%) | 159 (65.9%) | 225 (63.2%) | 0.487 |
6 Months | 12 Months | 24 Months | 36 Months | 60 Months | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group A (241 pts) | Group B (354 pts) | p | Group A (226 pts) | Group B (331 pts) | p | Group A (218 pts) | Group B (321 pts) | p | Group A (210 pts) | Group B (314 pts) | p | Group A (198 pts) | Group B (307 pts) | p | |
Weight (kg) * | 93.3 ± 6.4 | 98.4 ± 7.2 | <0.05 | 87.4 ± 6.9 | 90.7 ± 4.9 | <0.05 | 78.8 ± 7.8 | 79.5 ± 6.4 | 0.128 | 79.8 | 80.3 | 0.423 | 88.5 ± 5.9 | 90.1 ± 6.1 | 0.345 |
BMI (kg/m2) * | 32.3 ± 7.4 | 35.9 ± 5.2 | <0.05 | 28.1 ± 3.7 | 30.5 ± 4.1 | <0.05 | 26.7 ± 6.3 | 27.3 ± 4.7 | 0.348 | 27.1 ± 3.8 | 27.9 ± 6.9 | 0.486 | 29.1 ± 4.9 | 29.9 ± 5.2 | 0.215 |
%EWL | 66.3 ± 7.1 | 62.9 ± 7.5 | <0.05 | 70.7 ± 5.6 | 67.3 ± 7.8 | <0.05 | 79.7 ± 8.2 | 78.9 ± 7.4 | 0.245 | 78.4 ± 4.7 | 77.6 ± 5.9 | 0.348 | 70.1 ± 8.2 | 68.9 ± 5.8 | 0.157 |
%TWL | 31.9 ± 9.7 | 27.5 ± 9.9 | <0.05 | 32.9 ± 7.5 | 30.1 ± 4.9 | <0.05 | 36.8 ± 7.9 | 35.7 ± 7.3 | 0.318 | 35.7 ± 9.7 | 34.8 ± 7.2 | 0.319 | 34.7 ± 6.9 | 33.2 ± 5.8 | 0.229 |
Weight regain | 0 | 0 | - | 0 | 0 | - | 12 (5.5%) | 19 (5.9%) | 0.839 | 21 (10%) | 33 (10.5%) | 0.850 | 25 (12.6%) | 38 (12.4%) | 0.934 |
Insufficient weight loss | 1 (0.4%) | 2 (0.6%) | 0.799 | 4 (1.8%) | 7 (2.1%) | 0.773 | 9 (4.1%) | 22 (6.8%) | 0.146 | 18 (8.6%) | 36 (11.5%) | 0.285 | 22 (11.1%) | 40 (13.1%) | 0.521 |
Preoperative | 12 Months | 24 Months | 36 Months | 60 Months | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group A (241 pts) | Group B (354 pts) | p | Group A (226 pts) | Group B (331 pts) | p | Group A (218 pts) | Group B (321 pts) | p | Group A (210 pts) | Group B (314 pts) | p | Group A (198 pts) | Group B (307 pts) | p | |
GERD HRQL < 15 | 217 (90.4%) | 321 (90.6%) | 0.914 | 138 (61.1%) | 278 (83.9%) | <0.001 | 175 (80.3%) | 291(90.7%) | 0.008 | 191 (90.9%) | 301 (95.8%) | 0.211 | 188 (94.9%) | 299 (97.4%) | 0.148 |
GERD HRQL > 16 < 30 | 24 (9.9%) | 33 (90.4%) | 0.795 | 68 (30.1%) | 51 (15.5%) | <0.001 | 28 (12.8%) | 28 (8.7%) | 0.123 | 15 (7.2%) | 11 (3.6%) | 0.060 | 7 (3.6%) | 8 (2.6%) | 0.548 |
GERD HRQL > 31 | - | - | - | 20 (8.8%) | 2 (0.6%) | <0.001 | 15 (6.9%) | 2 (0.6%) | <0.001 | 6 (2.9%) | 2 (0.6%) | 0.042 | 3 (1.5%) | 0 | 0.334 |
Significant vomiting | - | - | - | 8 (3.5%) | 1 (0.3%) | 0.002 | 5 (2.3%) | 0 | 0.006 | 1 (0.5%) | 0 | 0.221 | 1 (0.5%) | 0 | 0.212 |
Intolerance to food | - | - | - | 2 (0.9%) | 0 | 0.035 | 0 | 0 | - | 0 | 0 | - | 0 | 0 | - |
Preoperative | 12 Months | 24 Months | 36 Months | 60 Months | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group A (241 pts) | Group B (356 pts) | p | Group A (198 pts) | Group B (287 pts) | p | Group A (162 pts) | Group B (258 pts) | p | Group A (122 pts) | Group B (229 pts) | p | Group A (98 pts) | Group B (187 pts) | p | |
Esophagitis A | 11 (4.5%) | 21 (5.9%) | 0.477 | 22 (11.1%) | 24 (8.4%) | 0.503 | 17 (10.5%) | 21 (8.1%) | 0.413 | 16 (13.1%) | 22 (9.8%) | 0.313 | 11 (11.2%) | 16 (8.6%) | 0.465 |
B | - | - | - | 12 (6.1%) | 3 (1.1%) | 0.001 | 9 (5.6%) | 2 (0.8%) | 0.002 | 6 (4.1%) | 1(0.4%) | <0.001 | 3 (3.1%) | 1 (0.5%) | 0.085 |
C | - | - | - | 2 (1%) | - | 0.088 | 1 (0.6%) | - | 0.206 | 1 (0.8%) | - | 0.170 | 1 (1%) | - | 0.166 |
D | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
Metaplasia | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Helicobacter Pylori | 22 (9.1%) | 29 (8.1%) | 0.673 | - | - | - | - | - | - | - | - | - | - | - | - |
Hiatal Hernia < 2 cm | 13 (5.4%) | 18 (5.1%) | 0.855 | 12 (6.1%) | 16 (5.6%) | 0.821 | 9 (5.6%) | 12 (4.6%) | 0.678 | 9 (7.3%) | 11 (4.8%) | 0.321 | 6 (6.1%) | 9 (4.8%) | 0.638 |
Preoperative | 12 Months | 24 Months | 36 Months | 60 Months | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group A (241 pts) | Group B (354 pts) | p | Group A (226 pts) | Group B (331 pts) | p | Group A (218 pts) | Group B (321 pts) | p | Group A (210 pts) | Group B (314 pts) | p | Group A (198 pts) | Group B (307 pts) | p | |
T2DM | 51 (21.2%) | 72 (20.3%) | 0.807 | 22 (9.7%) | 34 (10.2%) | 0.835 | 15 (6.9%) | 24 (7.4%) | 0.793 | 12 (5.7%) | 21 (6.7%) | 0.653 | 15 (7.6%) | 22 (7.2%) | 0.863 |
Hypertension | 159 (65.9%) | 225 (63.6%) | 0.545 | 45 (19.9%) | 70 (21.1%) | 0.723 | 22 (10.1%) | 34 (10.6%) | 0.851 | 14 (6.6%) | 22 (7.1%) | 0.880 | 17 (8.6%) | 25 (8.1%) | 0.860 |
Hyperlipidemia | 157 (65.1%) | 223 (62.9%) | 0.591 | 42 (18.5%) | 65 (19.6%) | 0.756 | 21 (9.6%) | 32 (9.9%) | 0.897 | 16 (7.6%) | 28 (8.9%) | 0.599 | 24 (12.1%) | 32 (10.4%) | 0.553 |
Obstructive Sleep Apnea | 113 (46.8%) | 169 (47.8%) | 0.838 | 41 (18.1%) | 57 (17.2%) | 0.742 | 31 (14.2%) | 46 (14.3%) | 0.971 | 14 (6.6%) | 25 (7.9%) | 0.199 | 12 (6.1%) | 22 (7.2%) | 0.628 |
Hyperuricemia | 37 (15.3%) | 49 (13.8%) | 0.606 | 22 (9.7%) | 31 (9.4%) | 0.884 | 7 (3.2%) | 12 (3.7%) | 0.744 | 1 (0.5%) | 1 (0.3%) | 0.774 | 0 (0%) | 1 (0.3%) | 0.421 |
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Gambardella, C.; Parisi, S.; Tolone, S.; Lucido, F.S.; del Genio, G.; Brusciano, L.; Esposito, R.; de Vito, D.; Docimo, L.; Pizza, F. Does Antrum Size Matter in Sleeve Gastrectomy? Volume II—A Retrospective Multicentric Study with Long-Term Follow-Up. J. Clin. Med. 2024, 13, 3912. https://doi.org/10.3390/jcm13133912
Gambardella C, Parisi S, Tolone S, Lucido FS, del Genio G, Brusciano L, Esposito R, de Vito D, Docimo L, Pizza F. Does Antrum Size Matter in Sleeve Gastrectomy? Volume II—A Retrospective Multicentric Study with Long-Term Follow-Up. Journal of Clinical Medicine. 2024; 13(13):3912. https://doi.org/10.3390/jcm13133912
Chicago/Turabian StyleGambardella, Claudio, Simona Parisi, Salvatore Tolone, Francesco Saverio Lucido, Gianmattia del Genio, Luigi Brusciano, Rosetta Esposito, Domenico de Vito, Ludovico Docimo, and Francesco Pizza. 2024. "Does Antrum Size Matter in Sleeve Gastrectomy? Volume II—A Retrospective Multicentric Study with Long-Term Follow-Up" Journal of Clinical Medicine 13, no. 13: 3912. https://doi.org/10.3390/jcm13133912