Association of Gut Microbiota Composition in Pregnant Women Colonized with Group B Streptococcus with Maternal Blood Routine and Neonatal Blood-Gas Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Enrollment of Patients and Healthy Controls
2.2. Sample Collection of Feces
2.3. Measurement of CBC in Pregnant Women
2.4. Neonatal Umbilical Artery Blood-Gas Analysis
2.5. 16S rRNA Gene Sequence Analysis
2.6. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Characteristic | GBS− (n = 14) | GBS+ (n = 12) | p-Value |
---|---|---|---|
Age (years) | 29.79 ± 2.97 | 30.58 ± 3.96 | 0.563 |
Gender | Female | Female | - |
WBC (×109/L) | 8.53 ± 1.20 | 9.37 ± 2.76 | 0.309 |
HGB (g/L) | 118.43 ± 8.21 | 118.67 ± 8.90 | 0.944 |
Neutrophil (%) | 72.21 ± 5.20 | 71.64 ± 9.48 | 0.849 |
Basophil (%) | 0.20 ± 0.30 | 0.17 ± 0.16 | 0.819 |
Lymphocyte (%) | 20.75 ± 4.87 | 21.46 ± 8.41 | 0. 792 |
Monocyte (%) | 5.75 ±0.10 | 5.09 ± 0.22 | 0.327 |
Eosinophil (%) | 0.97 ± 0.46 | 1.18 ± 1.11 | 0.536 |
Neutrophil count (×109/L) | 6.19 ± 1.17 | 6.80 ± 2.29 | 0.393 |
Basophil count (×109/L) | 0.01 ± 0.01 | 0.02 ± 0.02 | 0.704 |
Lymphocyte count (×109/L) | 1.74 ± 0.32 | 1.92 ± 0.67 | 0.370 |
Monocyte count (×109/L) | 0.49 ± 0.11 | 0.52 ± 0.27 | 0.668 |
Eosinophil count (×109/L) | 0.10 ± 0.04 | 0.10 ± 0.07 | 0.944 |
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Wang, Z.; Pu, W.; Liu, Q.; Zhu, M.; Chen, Q.; Xu, Y.; Zhou, C. Association of Gut Microbiota Composition in Pregnant Women Colonized with Group B Streptococcus with Maternal Blood Routine and Neonatal Blood-Gas Analysis. Pathogens 2022, 11, 1297. https://doi.org/10.3390/pathogens11111297
Wang Z, Pu W, Liu Q, Zhu M, Chen Q, Xu Y, Zhou C. Association of Gut Microbiota Composition in Pregnant Women Colonized with Group B Streptococcus with Maternal Blood Routine and Neonatal Blood-Gas Analysis. Pathogens. 2022; 11(11):1297. https://doi.org/10.3390/pathogens11111297
Chicago/Turabian StyleWang, Zhixia, Wenyuan Pu, Qi Liu, Meifeng Zhu, Qinlei Chen, Yingchun Xu, and Chunxiang Zhou. 2022. "Association of Gut Microbiota Composition in Pregnant Women Colonized with Group B Streptococcus with Maternal Blood Routine and Neonatal Blood-Gas Analysis" Pathogens 11, no. 11: 1297. https://doi.org/10.3390/pathogens11111297