Search Results (70)

Background: Traditional Male Circumcision (TMC) has been practiced in many parts of the world. However, the impact thereof on reducing HIV transmission is still unclear. This study aimed to examine the prevalence and determinants of TMC and the associated risk of HIV transmission in Lesotho. Method: Using data from the 2023–24 Lesotho Demographic and Health Survey, the analysis included a weighted sample of 3202 men aged 15–59 years. Missing data was addressed through multiple imputations, and multilevel logistic regression was used to assess the factors associated with TMC, incorporating intra-class correlation to evaluate cluster-level variation. Results: The findings revealed that 51.0% (95% CI: 49.3–52.7) of men in Lesotho had undergone TMC. Older men, particularly those aged 35 years and above, were more likely to be circumcised compared to younger men aged 15–24 years (AOR = 1.63; 95% CI: 1.46–1.86). Other individual-level factors positively associated with TMC included smoking, being married to one partner, previous sexual experience, and rural residence. Conversely, men with formal education, unknown or undisclosed HIV status, residing in the Berea or Maseru districts, and those from middle- or high-income households were less likely to undergo TMC. Conclusion: The study highlights significant variation in TMC practices across communities and identifies both individual and contextual factors influencing its uptake. These insights underscore the need for culturally sensitive, voluntary, and medically safe circumcision programs. Public health initiatives should consider these determinants when designing interventions to ensure a safer and more effective implementation of TMC in Lesotho. Full article

The Export-Led Growth Hypothesis (ELGH) posits that expanding exports drive long-run economic growth. While this has held true for several Asian economies, its effectiveness across African regional blocs remains underexplored. This study investigates the validity of ELGH in the East African Community (EAC) and Southern African Development Community (SADC), assessing whether exports significantly contribute to economic growth in these regions. The analysis covers 22 EAC and SADC economies from 1990 to 2022—regions marked by structural transformation efforts, trade liberalisation, and participation in the AfCFTA. A dynamic panel data model based on an augmented Cobb-Douglas production function is estimated using the System Generalised Method of Moments (System GMM) to address endogeneity and reverse causality. Granger causality tests supplement the analysis. Exports and technology significantly enhance GDP growth, while labour and FDI are statistically insignificant. Trade openness negatively affects growth, suggesting vulnerability to external shocks. A bidirectional Granger causality exists between exports and GDP. This study offers the first dynamic, bloc-level empirical evaluation of ELGH across EAC and SADC, incorporating trade-related interactions. Findings affirm ELGH’s relevance and stress the need for export diversification, technological upgrading, and institutional reform for sustained growth in Africa. Full article

In African patriarchal contexts, women have borne the dual responsibilities of mental and physical caregiving for their households and communities. These responsibilities often contribute to significant emotional, social, and economic burdens imposed by deeply entrenched gender and power structures. Alternative psychological coping mechanisms emerge to navigate these challenges, some deeply rooted in cultural and historical practices. One such practice is soil eating, which has been observed in various African communities. Historically linked to cultural and spiritual beliefs, soil eating has been largely unexplored from a psychological perspective. This paper examined soil eating as a coping strategy among women in Africa, investigating its role as a means of emotional relief, resistance, or a symbolic reclamation of agency in the face of oppression. Drawing on the indigenous knowledge systems (IKS) of eZiko siPheka siSophula as a psychological framework, this study engaged sixteen women aged 20 to 89 in Ha Makintane Lesotho to participate in focus group discussions and reveal their personal narratives, cultural traditions, and the intersections of gender, race, and class to understand how this practice helps them manage their mental and emotional toll of patriarchal dominance. This research contributes to discussions on resilience, survival, and the psychological strategies developed by marginalized communities, shedding light on the complex interplay between cultural practices, mental health, and gendered experiences of power. Full article

Renewable energy has emerged as a transformative and essential alternative in the global energy sector. Many countries are striving to achieve the Sustainable Development Goals (SDGs) established by the United Nations for 2030, particularly the goal of ensuring that all individuals have access to clean and affordable energy. This paper re-examines the impact of economic growth (EG), trade openness (TO), exchange rates (ER), foreign direct investment (FDI), green finance (GF), and oil prices (OL) on renewable energy consumption (REC) across 14 Southern African countries: South Africa, Botswana, Lesotho, Namibia, Tanzania, Madagascar, Mauritius, Kenya, the Comoros, Zambia, Eswatini, Rwanda, Angola, and Mozambique, during the period of 2000 to 2022. This study employed cointegration and unit root tests, as well as the RALS-EG and MMQR models, to estimate the long-run relationships among the variables. The results reveal that renewable energy consumption is positively and directly related to economic growth, trade openness, exchange rates, green finance, and foreign direct investment across all quantiles (q05–q95), with no evidence of asymmetric effects. These findings suggest that economic growth, green finance, and foreign direct investment are crucial for fostering renewable energy innovation in Southern African countries. Policymakers are encouraged to prioritize strategies that enhance these factors as a foundation for achieving sustainable energy solutions. Full article

This study projects the performance of maternal and child mortalities in relation to the SDGs target (70 maternal deaths and 25 child deaths) by year 2030, based on three simulation scenarios of public health expenditures (PHEs). In essence, this study investigates the predictability of PHE in explaining maternal and child mortalities in a bid to confirm the possibility of meeting the SDGs target. The SSA is known to be facing critical health challenges; this study contributes to the problem underlying the health sector by forecasting PHEs in relation to goal 3 because the knowledge of correlation and threshold relationship between PHE and health outcomes, as seen in previous studies, may not be adequate to prepare the SSA countries towards achieving the SDGs target. This study uses Feasible Quasi-Generalised Least Squares as a baseline forecasting approach for 25 selected SSA countries. An increase in the PHE by 30 percent from the current level shows that only Botswana, Namibia, and South Africa will achieve the SDGs target of 70 maternal deaths, while Burundi, Cameroon, Central African Republic, Cote d’Ivoire, Eswatini, Lesotho, Mauritania, Niger, Nigeria, Tanzania, and Togo may have to bear more than 200 maternal deaths by 2030. In contrast, about 60 percent of the countries will achieve the SDGs target for child mortality. PHEs must meet the 30% increase forecasted for a reduction in mortality, being the benchmark that will enable the SSA region to achieve the SDGs target by year 2030. Full article

Meaningful learning is central to every teaching and learning exercise. The attainment of this goal in the face of the cultural diversity of students suggests the use of culturally sensitive approaches. Several studies have shown that teachers are adopting tenets of culturally relevant education to promote meaningful learning of STEM subjects for culturally, linguistically, and socially diverse populations of learners. In Africa, the culturo-techno-contextual approach (CTCA) has witnessed great exploration in Science Technology, Engineering, and Mathematics (STEM) education to ensure students learn meaningfully. However, missing in the literature is a systematic review study on the use of CTCA in STEM teaching and learning. By synthesizing the findings of studies on the use of CTCA, this review highlights the unique contributions of CTCA to promoting meaningful learning of STEM subjects for African learners through quality research reports connecting CTCA to students’ positive outcomes in science, technology, and mathematics from 2015 to 2025. Data were sought from peer-reviewed experimental studies found in Google Scholar, ResearchGate, Scopus, and Web of Science with specific selection criteria, and 24 studies were found eligible for inclusion. The findings demonstrated that CTCA has been repeatedly effective in breaking the barriers to meaningful learning of STEM subjects, helping students to understand difficult STEM concepts and improving their academic achievement. Additionally, the findings indicated several implications for practice and future research on the use of CTCA. Hence, we concluded that this review study will be a useful reference for teachers, STEM educators, and educational researchers willing to rewrite the narratives of STEM learning in Africa by decolonizing STEM education and bringing the African indigenous knowledge to the frontier of STEM teaching and learning. Full article

Wheat plants encounter both biotic and abiotic pressure in their surroundings. Among the biotic stress factors, the Russian wheat aphid (RWA: Diuraphis noxia Kurdjumov) decreases grain yield and quality. The current RWA control strategies, including resistance breeding and the application of aphicides, are outpaced and potentially environmentally harmful. Alternatively, priming can stimulate defence responses to RWA infestation. This study investigated the priming potential of two priming agents, avirulent Puccinia triticina (Pt) isolates and salicylic acid (SA), against RWA infestation. The priming effect of Pt isolates and SA in reducing RWA-induced leaf damage and increased antioxidant activities is an indication of defence responses. Selected South African wheat cultivars and Lesotho landraces, grown under greenhouse conditions, were inoculated with Pt isolates (UVPt13: avirulent, UVPt26: virulent) and treated with SA at the seedling or booting stages. The leaf damage rating score was used for phenotyping. The antioxidant-mediated defence responses were evaluated in three selected cultivars for further priming investigation. Our results revealed that the priming agents significantly reduced the leaf damage in most cultivars at both growth stages, and UVPt13 and SA priming significantly (p ≤ 0.05) increased superoxide dismutase, peroxidase, and ascorbate peroxidase activities. However, catalase activity exhibited a more pronounced decline in plants treated with the UVPt13 isolate. The Pt isolate priming was more efficient than the SA application. However, it is crucial to investigate the potential of effectors from the avirulent Pt isolate to prime wheat plants for resistance against RWA infestation. This could contribute to developing strategies to enhance crop protection and relieve pest pressure in wheat production. Full article

MADS-box genes are essential for plant development and secondary metabolism. The majority of genes within a genome exist in a gene family, each with specific functions. Ginseng is an herb used in medicine for its potential health benefits. The MADS-Box gene family in Jilin ginseng has not been studied. This study investigated the evolution and structural and functional diversification of the PgMADS gene family using bioinformatics and analyzed gene expression through methyl jasmonate (MeJA) regulation. The results revealed that the evolution of the PgMADS gene family is diverged into ten clusters of a constructed phylogenetic tree, of which the SOC1 cluster is the most prevalent with a higher number of PgMADS genes. Despite their distinct evolutionary clusters, a significant number of members contains common conserved motifs. The PgMADS gene family was functionally differentiated into three primary functional categories, biological process, molecular function, and cellular component. Their expression is variable within a tissue, at a developmental stage, and in cultivars. Regardless of the diversity of the functions of PgMADS genes and evolution, their expression correlated and formed a co-expression gene network. Weighted gene co-expression network analyses identified hub genes that could be regulating ginsenoside biosynthesis. Interestingly, the family also is involved in MeJA regulation. These findings provide a valuable reference for future investigations on PgMADS genes. Full article

(1) Background: HIV drug resistance (HIVDR) poses a significant challenge to the effectiveness of antiretroviral therapy and the overall management of HIVand AIDS. Understanding the predictors of HIVDR is critical for developing strategies to mitigate its impact. The objectives of this study were to identify the predictors of HIVDR among Zimbabwe Population-Based HIV Impact Assessment (ZIMPHIA 2020) study participants, a national population-based survey. (2) Methods: Data from people living with HIV who participated in the ZIMPHIA 2020 were used to determine the predictors of HIVDR. (3) Results: The prevalence of HIVDR was 44.9%. Acquired HIVDR was present in 76.1% of people with a virological failure and transmitted resistance is 22.6% in naïve individuals. Factors associated with HIVDR in adjusted analysis were the number of lifetime sexual partners (aOR = 1.03, 95% CI: 1.01–1.06, p = 0.017), each additional year since the first HIV positive result (aOR = 1.17, 95% CI: 1.09–1.25, p < 0.01), each additional year on ART (aOR = 1.14, 95% CI: 1.06–1.23, p = 0.001), initiating ART before 2014 (aOR = 3.08, 95% CI: 1.72–5.49, p = 0.020), ever had switched antiretrovirals (aOR = 2.47, 95% CI: 1.15–5.29, p = 0.020) or had ever had a viral load test (aOR = 2.54, 95% CI: 1.54–4.17, p < 0.001) and a CD4 count < 350 (aOR = 2.04, 95% CI: 1.48–2.83, p < 0.01), while age ≥ 50 (aOR = 0.56, 95% CI: 0.32–0.98, 32 p = 0.04), condom use at last encounter (OR: 0.49, 95%CI: 0.33–0.73, p < 0.001), and not being on ART (aOR = 0.09, 95% CI: 0.06–0.13, p < 0.01) were associated with reduced odds of HIVDR. Conclusions: HIVDR was high among the participants. There is a need to address HIVDR and enhance the mechanisms already in place. This study introduces more information that would help in developing targeted interventions to prevent HIVDR and improve patient outcomes. Full article

Background: Hands are critical vectors for microorganisms that cause healthcare-associated infections (HAIs). Hand hygiene, being done the right way, at the right time, and being given the right priority in a healthcare setting is an effective strategy to reduce HAIs and associated costs. Different strategies have been put in place to help improve hand hygiene compliance among healthcare workers; amongst them, continuous training is advised at all levels of care. Aim: This study, focusing on nursing students, aimed to describe their knowledge, attitudes, and perceptions towards hand hygiene, highlighting their crucial role in maintaining health and preventing infections. Methods: This study was a quantitative cross-sectional study. One hundred and fourteen questionnaires were distributed; 103 were filled out and returned by willing students at Maluti Adventist College, thus a 90% response rate. Results: 62% (64) demonstrated moderate knowledge, all had positive attitudes, and 61% (63) had a positive perception towards hand hygiene. There was a significant (p-value = 0.012) association between knowledge and training. Conclusions and recommendations: These provide valuable input for enhancing the World Health Organization’s (WHO) hand hygiene multimodal strategy, the SAFE LIFE Clean YOUR HAND campaign, and healthcare workers’ teaching curriculum. All stakeholders should implement strategies that prioritize knowledge dissemination to promote effective hand hygiene practices among healthcare workers worldwide. Full article

Exposure to respirable crystalline silica dust is one of the most common and severe risks due to the associated health outcomes among workers and results in many occupational-related lung diseases, such as silicosis and lung cancer. The study aimed to determine knowledge, attitudes, and practices on occupation health and safety among mine workers exposed to crystalline silica dust in Lesotho. A descriptive retrospective cross-sectional study design was used in the study. A record review guide was used to retrieve secondary data from the Southern Africa Tuberculosis and Health Systems Support (SATBHSS) project, which were thereafter entered into STATA software, version 17 for descriptive and inferential analysis. The study participants were purposively selected. Most participants were between the ages of 31 to 40 years of age and there was a significant difference between the genders with 35 (9%) females and 350 (91%) males. The majority of the participants had a high school level of education (305, 79%). The knowledge was generally positive in the study with a knowledge score mean of 13.43 (standard deviation: 2.99). The miners agreed with most attitude statements except for A1 (25%), A2 (35%), A3 (18%), and A4 (31%). The practice of exposed mine workers in the study was influenced by working in a dolerite mine (p = 0.003), knowledge score (p ˂ 0.001), and having an attitude about health and safety rules at the mine (p ˂ 0.001; 95% CI: 0.92 to 0.79), while age was a protective factor in the study. The findings of this study highlighted positive knowledge, attitudes, and practices toward occupational health and safety among mine workers. However, more educational programs can be implemented to ensure all mine workers understand the importance of good knowledge, positive attitude, and appropriate practices towards occupational health and safety in their environment. Full article

Lumpy skin disease is one of the fast-spreading viral diseases of cattle and buffalo that can potentially cause severe economic impact. Lesotho experienced LSD for the first time in 1947 and episodes of outbreaks occurred throughout the decades. In this study, eighteen specimens were collected from LSD-clinically diseased cattle between 2020 and 2022 from Mafeteng, Leribe, Maseru, Berea, and Mohales’ Hoek districts of Lesotho. A total of 11 DNA samples were analyzed by PCR and sequencing of the extracellular enveloped virus (EEV) glycoprotein, G-protein-coupled chemokine receptor (GPCR), 30 kDa RNA polymerase subunit (RPO30), and B22R genes. All nucleotide sequences of the above-mentioned genes confirmed that the PCR amplicons of clinical samples are truly LSDV, as they were identical to respective LSDV isolates on the NCBI GenBank. Two of the elevem samples were further characterized by whole-genome sequencing. The analysis, based on both CaPV marker genes and complete genome sequences, revealed that the LSDV isolates from Lesotho cluster with the NW-like LSDVs, which includes the commonly circulating LSDV field isolates from Africa, the Middle East, the Balkans, Turkey, and Eastern Europe. Full article

Artemisia afra is a plant that grows in the northern, central, and coastal regions of South Africa, as well as in neighboring countries such as Eswatini and Lesotho. These phytochemicals can be used as active compounds in plant-based medicine. Therefore, it is important to determine how plant minerals and phytochemicals, particularly bioactive compounds, are affected by the geolocation in which they grow. This study aimed to evaluate the mineral and phytochemical properties of A. afra genotypes in the southern regions of Africa. Leaf samples of A. afra genotypes were collected from Lesotho, in Mohale’s Hoek and Roma. In South Africa, leaf samples were collected in Wepener and Hobhouse, and 80 plants were randomly selected for phytochemical and mineral analyses. This study reveals that phosphorus, calcium, potassium, iron, and zinc loaded positively to the first principal component, while copper loaded positively to the second principal component with variabilities of 29.95% and 21.12%, respectively. Furthermore, both the Mohale’s Hoek and Hobhouse genotypes exhibited relatively high levels of ascorbic acid, phenolic compounds, flavonoids, and tannins. It is worth noting that genotypes from Roma and Wepener showed higher levels of foliar magnesium. Thus, the Mohale’s Hoek and Hobhouse genotypes could be recommended for their better phytochemical contents. Full article

Remittances are essential to the sustainability of economies in mountainous regions that face massive labour migration due to limited income generation and employment opportunities. In 2021, the share of remittances in GDP in the top 10 mountainous economies in the world was over 20%. Nonetheless, most are characterised by relatively lower GDP per capita and high poverty levels. Drawing a comparison with other mountainous areas, Phuthaditjhaba, an emerging mountainous city of South Africa on the border with Lesotho, faces similar out-migration and inferior socio-economic parameters. A global systematic literature review on the impact of remittances on livelihoods, specifically targeting mountainous areas, is missing. We, therefore, interrogate the role that remittances can play in Phuthaditjhaba. To inform our intended research, we seek to draw lessons from evidence on how migration and remittances affect mountainous communities globally. Accordingly, we carry out a systematic literature review (SLR) based on an updated Preferred Reporting Item for Systematic Reviews and Meta-Analysis (PRISMA) 2020 statement supported by bibliometric (co-word) analysis (BA) in VOSViewer. We collected data from the Scopus and Dimensions websites and drew 165 publications, of which only 88 were included after exclusion and inclusion assessments. The PRISMA results show that Mountain Research and Development, Russell King, and Nepal are the most productive and cited journal, the most productive and cited author, and the most researched country, respectively. The bibliometric analysis on keyword co-occurrences revealed that women, agriculture, labour migration, land management, forest, and poverty are the research hotspots. In light of these findings, we proffer important recommendations for future researchers and policymakers and identify thematic research areas for Phuthaditjhaba. Full article

Promoting human mobility and reducing inequality among countries are the Sustainable Development Goals’ (SDGs) targets. However, measuring human mobility, assessing its heterogeneity and changes, and exploring associated mechanisms and context effects are still key challenges, especially for developing countries. This study attempts to review the concept of human mobility with complex thinking, assess human mobility across forty countries in Sub-Saharan Africa (SSA), and examine the effect of climatic and socioeconomic factors. Based on the coined definition of human mobility, international migration and cross-border trips are taken to assess human mobility in terms of permanent migration and temporary moves. The forty SSA countries are hence classified into four mobility groups. Regression models are performed to identify key determinants and estimate their effects on mobility. The results reveal that seven of these forty countries had a high mobility, whereas most experienced a decline in permanent migration. Lesotho, Cabo Verde, and Namibia presented high temporary moves, while Eritrea, Rwanda, Equatorial Guinea, and Liberia had a high permanent migration. Climatic and socioeconomic conditions demonstrated significant effects on mobility but were different for temporary moves and permanent migration. Wet extremes reduced mobility, whereas extreme temperature variations had positive effects. Dry extremes promoted permanent migration but inhibited temporary moves. Economic wealth and political instability promoted permanent migration, while the young population counteracted temporary moves. Food insecurity and migrant networks stimulated human mobility. The analysis emphasises the interest in analysing human mobility for risk reduction and sustainability management at the multi-county level. Full article