Search Results (227)

This study presents a mathematical model to describe the transmission dynamics of asthma, explicitly accounting for the impact of dust waves and airborne particulate matter in the environment, recognized as key triggers of asthma exacerbations. The model incorporates a single endemic equilibrium point, which is shown to be locally asymptotically stable. To mitigate the burden of asthma, we employed the Pontryagin Maximum Principle within an optimal control framework, incorporating three time-dependent intervention strategies: vaccination, treatment, and avoidance of environmental triggers such as dust exposure. The model was numerically solved using the fourth-order Runge–Kutta method in conjunction with a forward–backward sweep algorithm to investigate the effects of various control combinations on the prevalence of asthma. Additionally, a comprehensive cost-effectiveness analysis was conducted to evaluate the economic viability of each strategy. The results indicate that the combined application of vaccination and treatment is the most cost-effective approach among the strategies analyzed, significantly reducing the number of asthma cases at minimal cost. All simulations and numerical experiments were performed to validate the theoretical findings and quantify the effectiveness of the proposed interventions under realistic environmental conditions driven by dust activity. The model highlights the importance of integrated medical and environmental control policies in mitigating asthma outbreaks, particularly in regions frequently exposed to dust storms. Full article

Considering the serious hazard of respiratory dust in underground coal mines and the low efficiency of traditional dust-reduction technology, this study optimizes the atomisation parameters of the gas–liquid two-phase flow nozzle through numerical simulation and experimental testing, and designs an on-board dust-reduction system. Based on the Fluent software (version 2023 R2), a flow field model outside the nozzle was established, and the effects of the air supply pressure, gas-phase inlet velocity, and droplet mass flow rate on the atomisation characteristics were analyzed. The results show that increasing the air supply pressure can effectively reduce the droplet particle size and increase the range and atomisation angle, and that the dust-reduction efficiency is significantly improved with the increase in pressure. The dust-reduction efficiency reached 69.3% at 0.6 MPa, which was the economically optimal operating condition. Based on the parameter optimization, this study designed an annular airborne gas–liquid two-phase flow dust-reduction system, and a field test showed that the dust-reduction efficiency of this system could reach up to 86.0%, which is 53.5% higher than that of traditional high-pressure spraying, and that the dust concentration was reduced to less than 6 mg/m³. This study provides an efficient and reliable technical solution for the management of underground coal mine dust and guidance for promoting the development of the coal industry. Full article

Since airborne microplastics (AMPs) are a recent and unexplored field of study, there are several unresolved issues regarding their effects on plants. The accumulating potential of AMPs and their effect on the biochemical parameters of ten different plant species in an Indian city environment were assessed. The four types of AMPs deposited in the phyllosphere—fragment (30.76%), film (28.95%), fiber (22.61%), and pellet (17.68%)—were examined using stereomicroscopy and fluorescence microscopy. The air pollution tolerance index (APTI) was determined, and other biochemical parameters such as proline, phenol, malondialdehyde, carotenoids, superoxide dismutase, catalase, and peroxidase were also measured. The findings showed that in the case of polymers type, PE (30%) was more abundant than others, followed by PET (17%), PP (15%), PVC (13%), PVA (10%), PS (7%), ABS (5%), and PMMA (3%). Clerodendrum infortunatum L., Calotropis procera (Aiton) W.T. Aiton, and Mangifera indica L. all showed a strong APTI and also exhibited significantly higher amounts of AMP accumulation. Principal component analysis showed a stronger association between phyllospheric AMPs and biochemical parameters. Additionally, the correlation analysis revealed that the presence of accumulated AMPs may significantly influence the biochemical parameters of the plants. Thus, it can be concluded that the different plant species are uniquely specialized in AMP accumulation, which is significantly impacted by the plants’ APTI as well as other biochemical parameters. Full article

Background: Lithium is an essential commodity; however, its mining and processing can expose miners to airborne contaminants such as inhalable dust, respirable dust and respirable crystalline silica. These exposures may adversely affect respiratory health. To protect the health of miners, exposure assessment and control activities are required, followed by respiratory health monitoring to assess the effect of exposure on respiratory health. This study aimed to investigate the relationship between workgroup exposure to airborne contaminants and respiratory health. To determine group exposure levels, exposure data was collected at the group level, which limits individual-level inference, followed by health monitoring. Methods: Industry health monitoring data were collected from miners in three surface lithium mines in Western Australia for the period between October 2023 and October 2024. Miners from Management Administration & Technical, Crusher/Dry/Wet Plant, and Laboratory Operations participated in a pulmonary function test, completed a health and exposure questionnaire and underwent a low dose high-resolution computed tomography. Multivariable linear and logistic regression models were fitted to identify factors associated with lung function and respiratory symptoms. Results: Older age, smoking and pre-existing respiratory conditions were correlated with poor respiratory airflow. The odds of having a respiratory obstruction or restriction were significantly higher by 3.942 and 2.165 times respectively, for miners who were 40 years old or above, and those who had existing diagnosed respiratory medical conditions. The risk of coughing among current smokers was more than four times higher compared to non-smokers. In addition, working in Crushing and Processing was significantly associated with the risk of experiencing respiratory symptoms compared to working in Management Administration & Technical and Laboratory Operations. Conclusions: The study demonstrated that respiratory health was influenced by non-work-related risk factors. Based on these results, it is recommended that health promotion programs be developed and implemented to empower miners to cease smoking and to manage non-work-related respiratory conditions. Full article

The dynamic relationship between microplastics (MPs) in the air and on the Earth’s surface involves both natural and anthropogenic forces. MPs are transported from the ocean to the air by bubble scavenging and sea spray formation and are released from land sources by air movements and human activities. Up to 8.6 megatons of MPs per year have been estimated to be in air above the oceans. They are distributed by wind, water and fomites and returned to the Earth’s surface via rainfall and passive deposition, but can escape to the stratosphere, where they may exist for months. Anthropogenic sprays, such as paints, agrochemicals, personal care and cosmetic products, and domestic and industrial procedures (e.g., air conditioning, vacuuming and washing, waste disposal, manufacture of plastic-containing objects) add directly to the airborne MP load, which is higher in internal than external air. Atmospheric MPs are less researched than those on land and in water, but, in spite of the major problem of a lack of standard methods for determining MP levels, the clothing industry is commonly considered the main contributor to the external air pool, while furnishing fabrics, artificial ventilation devices and the presence and movement of human beings are the main source of indoor MPs. The majority of airborne plastic particles are fibers and fragments; air currents enable them to reach remote environments, potentially traveling thousands of kilometers through the air, before being deposited in various forms of precipitation (rain, snow or “dust”). The increasing preoccupation of the populace and greater attention being paid to industrial ecology may help to reduce the concentration and spread of MPs and nanoparticles (plastic particles of less than 100 nm) from domestic and industrial activities in the future. Full article

Cyanobacteria can produce a wide range of toxins which have acute and chronic adverse health effects. Affecting a variety of mammalian systems, they are generally characterized according to their mode of action and the organs affected. Cyanobacterial neurotoxins are one cyanotoxin class that can negatively affect human health, and representatives of other cyanotoxins classes are increasingly showing neurotoxic effects. Of the various human exposure routes to cyanobacterial toxins, the significance of the airborne and inhalation route requires much greater clarity and understanding. People may be exposed to mixtures of cyanobacterial neurotoxins through the inhalation of sprays and dust, along with the potential to directly enter the central nervous system when crossing the blood-brain barrier. This review aims to summarize the current state of knowledge concerning airborne cyanobacterial neurotoxins, research gaps, health effects, and the need for management practices to protect human and animal health. Full article

Airborne micro and nanoplastics (MPs/NPs) are a growing issue due to their possible health hazards. Since the current bibliography lacks a thorough evaluation, this review examines the sources, environmental dynamics, and health impacts of airborne MPs/NPs. Through atmospheric transport processes, these neo-pollutants spread around the world after being released, potentially settling in urban and remote areas. This review is the first to compare active and passive aerosol sampling methods, and microscopy, thermochemical, and spectroscopy analytical techniques, with a focus on their limitations in precisely quantifying micro-nanoscale plastic particles. It also draws attention to the potential toxicological effects of inhaled MPs/NPs, which can lead to oxidative stress, respiratory inflammation, and other negative health consequences. This review concludes by examining how airborne MPs/NPs may worsen their ecological impact by serving as carriers of hazardous chemicals and microbial pollutants. Despite growing awareness, there still are many unanswered questions, especially about the impact of long-term exposure and how atmospheric conditions affect the spread of MPs/NPs. The aim of this review was to bring attention to the issue of airborne MP/NP effects and to promote the development of advanced monitoring systems, a new multidisciplinary scientific field for the study of these novel pollutants, and global regulatory frameworks. Full article

This scoping review examines the distribution, sources, and characterization of atmospheric microplastics (AMPs) in Southeast Asia (SEA), following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. A comprehensive search of Scopus and PubMed identified 58 relevant articles, with 16 meeting the inclusion criteria. Findings indicate high microplastic (MP) concentrations in urban centres, notably in Malaysia, Indonesia, and Thailand, a pattern driven by rapid urbanisation, industrial emissions, textile production, and insufficient waste management. Predominant polymer types include polyethylene (PE), polypropylene (PP), and polyester (PET), with fibres and black particles being the most common forms. Black particles, often linked to tire wear and vehicular emissions, underscore traffic pollution’s role in AMP distribution, while PET fibres reflect the influence of SEA’s textile industry. Geographic gaps were observed, with limited studies in countries such as Cambodia and Laos. The review highlights the need for standardised sampling and quantification methods to ensure data comparability and calls for expanded research into rural and coastal regions. Future studies should prioritise longitudinal investigations into the effects of chronic exposure on health; this is particularly relevant for nanoplastics (NPs) because of their greater potential for biological penetration. These insights form a crucial foundation for mitigating AMP pollution in SEA. Full article

Several studies have reported the incidence of fungi and mycotoxins in coffee beans; however, there are few reports related to occupational exposure to these agents at coffee dry milling industries. The aim of this review was to identify and to analyze studies assessing occupational exposure to fungi and mycotoxins in coffee industries. Therefore, a systematic literature search was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology and focusing on the assessment of occupational exposure to fungi and mycotoxins in the coffee industry. In these papers, different environmental matrices were considered in evaluating occupational exposure, but the most used matrix was airborne dust (four of the five studies). Airborne fungi were sampled using active (four of the five studies) and passive sampling. Only the most recent of the studies (2022) identified microorganisms by their genera and species, and only two groups of mycotoxins were analyzed in the studies considered, namely, Ochratoxin A and Aflatoxins. None of the studies reported data on both fungi and mycotoxins. The fungal genera identified in these occupational environments included Cladosporium, Paecilomyces, Aspergillus, Penicillium, and other genera. Among the mycotoxins, only aflatoxins and ochratoxin A were investigated. Occupational exposure to these biological agents may lead to several health effects. Fungal spores and fragments can cause respiratory diseases such as asthma, allergic rhinitis, bronchitis, and hypersensitivity pneumonitis. Additionally, the mycotoxins studied—particularly Aflatoxins and Ochratoxin A—are associated with serious toxicological effects. Coexposure to both fungi and mycotoxins may enhance health risks and should be carefully considered in occupational risk assessments. Considering the possible effects related to exposure to fungi and mycotoxins and the number of workers involved in this type of industry in the world, more studies should be developed. This is the first review to systematically consolidate data on occupational exposure to both fungi and mycotoxins specifically within the coffee industry, highlighting existing knowledge gaps and the need for targeted risk assessments in coffee-producing settings. Full article

Safety in workplaces is a requirement for work sustainability. Construction workers are frequently exposed to dangerous airborne substances. While previous studies examined chemical risks in other sectors, there is limited research on occupational chemical risk perception (OCRP) among construction workers. This study focuses on evaluating OCRP in construction workers and identifying its association with socio-demographic, occupational, and training variables. In L’Aquila, Italy, a sample of male construction workers involved in post-earthquake reconstruction were enrolled in this cross-sectional study. Chemical hazard perception, occupational exposure, personal protective equipment (PPE) use, and training were all covered by our questionnaire. Although the involved 117 workers appear to be aware of dust-related risks and asbestos-related diseases, 53% think that there is no asbestos at their worksite. Respiratory protection equipment was used by 36% of the respondents. OCRP was associated with refresher training (OR = 2.56; p = 0.025); perception of noise (OR = 10.03; p = 0.027); and solar radiation (OR = 26.07; p = 0.001). Although we observed an appropriate awareness of some occupational hazards, gaps between awareness, hazard perception, and protective behavior were evident. Comprehensive site inspections and improved risk communication are necessary to assess chemical hazards and enhance work sustainability. Full article

Airborne fine-dust pollution poses a significant threat to both respiratory and skin health; however, the skin’s wound-healing process in response to such exposure remains underexplored. Therefore, this study examined the effect of fine-dust-model compounds, specifically polycyclic aromatic hydrocarbons (PM₁₀-PAHs) and trace-metal-containing particles (PM₁₀-Trace), on the wound-healing process using human skin equivalents reconstructed with collagen-based biomaterials and human skin cells. Our findings revealed that fine-dust exposure significantly delayed wound closure by 2–3 times compared with unexposed controls, impairing re-epithelialization. Live imaging of wound-healing dynamics revealed that trace-metal-containing particles had a more pronounced inhibitory effect than polycyclic aromatic hydrocarbons. Furthermore, fine-dust exposure elevated protease-activated receptor-1 (PAR1) expression by up to 161%, indicating significant physiological disruption. Additionally, fine-dust exposure triggered inflammation and oxidative stress, leading to structural and functional damage in the reconstructed skin. These results provide critical insights into how airborne pollutants disrupt skin repair mechanisms and highlight the need for targeted strategies to mitigate their harmful effects. Full article

Spain exhibits significant climatic variability across its regions, ranging from the humid oceanic climate in the north to the Mediterranean and stepped climates in the southern and central areas. These climatic differences influence environmental allergen exposure, which may, in turn, affect allergic sensitization patterns in the pediatric population. Variations in temperature, humidity, and airborne allergen distribution, such as pollen, dust mites, animal epithelia, and mold, contribute to regional disparities in allergic responses among children. Understanding how climatic conditions shape allergen recognition patterns across different geographical areas is essential for improving allergy prevention and management strategies. This study aims to shed light on this issue by identifying sensitization patterns in a pediatric population of 236 patients (with 2 age groups analyzed: 6–10 and 11–15 years old) from different climatic regions of Spain. Skin tests with standard aeroallergens were performed, and specific IgE (sIgE) analysis by Allergy Explorer of Macroarray Diagnostic test (ALEX²) and Western blot. The results revealed different sensitization trends across patients from the eight cities analyzed (Barcelona, Granada, Lugo, Sagunto, Santiago de Compostela, Valencia, and Zaragoza). Full article

An integral part of daily dental practice is preparing and polishing placed composite restorations. When these procedures are performed, significant amounts of composite dust are released from the grinding material. This systematic review aims to enhance the existing body of knowledge, encourage further dialogue, and expand the understanding of composite dust and its related risks. Following inclusion and exclusion criteria, twelve studies were included. Several studies highlight that composite dust contains nanoparticles capable of deep lung penetration, posing significant health risks to both dental staff and patients. Inhalation of composite dust can lead to respiratory diseases such as pneumoconiosis. Studies have shown that water cooling during composite grinding reduces dust emissions but does not eliminate them completely. Researchers suggest that thermal degradation of the composite material, not just filler particles, may be the source of the nanoparticles. In vitro studies have shown the toxicity of composite dust to bronchial and gingival epithelial cells, especially at high concentrations. Further research is needed on the health effects of composite dust and the development of effective methods to protect staff and patients. Full article

Asbestos is a fibrous variety of certain minerals, some of which occur naturally as an accessory to a wide variety of mineral resources. Although asbestos itself has been historically mined for various useful properties, the negative health effects of asbestos dust have greatly diminished it as a useful earth material, as many countries have banned the use of these fibrous minerals based on those health concerns. Resulting regulations of asbestos have focused primarily on intentionally mined material used in product manufacturing, such as building materials made with beneficiated asbestos and their derivative exposures, e.g., airborne asbestos in schools with asbestos-containing materials. The hazards of asbestos as unintended byproducts have not been as extensively considered, although this “contamination” has been repeatedly observed in common earth materials including talc, vermiculite, sand, and gravel. This study reveals such contamination of ornamental and dimension stone commonly referred to as “marble”. Asbestos types that can be associated with certain Indian marble reserves include asbestiform tremolite, actinolite, anthophyllite, and chrysotile asbestos. This case reveals such contamination in a marble reserve in Rajsamand, Rajasthan. At this location, marble dust in slurry is disposed at waste collection points, unfortunately including a location now open to the public that has become a tourist destination. Using Transmission Electron Microscopy (TEM) in this study, dust from this location revealed abundant tremolite asbestos fibres in the disaggregated dust. This poses potential health risks to the workers, bystanders, and tourists that may be exposed to this recognized carcinogen, a known cause of mesothelioma, lung cancer, and other asbestos-related diseases. Full article

Background and Objectives: Persistent exposure to airborne fine dust (FD) particles contributing to air pollution has been linked to various human health issues, including respiratory inflammation, allergies, and skin diseases. We aimed to identify potential seaweed anti-inflammatory bioactive reagents and determine their effects on systemic inflammatory responses induced by FD particles. Materials and Methods: While exploring anti-inflammatory bioactive reagents, we purified compounds with potential anti-inflammatory effects from the seaweed extracts of Ecklonia cava, Ecklonia stolonifera, and Codium fragile. Structural analyses of the purified compounds siphonaxanthin (Sx), fucoxanthin (Fx), dieckol (Dk), and phlorofucofuroeckol-A (PFF-A) were performed using NMR and LC-MS/MS. Results: Notably, these compounds, especially PFF-A, showed significant protective effects against FD-induced inflammatory responses in RAW 264.7 cells without cytotoxicity. Further investigation of inflammatory-associated signaling demonstrated that PFF-A inhibited IL-1β expression by modulating the NF-κB/MAPK signal pathway in FD-induced RAW 264.7 cells. Additionally, gene profiling revealed the early activation of various signature genes involved in the production of inflammatory cytokines and chemokines using gene profiling. Treatment with PFF-A markedly reduced the expression levels of pro-inflammatory and apoptosis-related genes and even elevated the Bmp gene families. Conclusions: These results suggested that PFF-A is a potential natural therapeutic candidate for managing FD-induced inflammatory response. Full article