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19 pages, 6081 KB  
Article
Daylight Sonography: Clinical Relevance of Color-Tinted Ultrasound Imaging
by Christoph F. Dietrich, Matthias Wüstner, Christian Jenssen, Daniel Merkel and Jörg S. Bleck
Life 2025, 15(11), 1672; https://doi.org/10.3390/life15111672 (registering DOI) - 27 Oct 2025
Abstract
Daylight sonography refers to the technique of using color-tinted, brightness and contrast-controlled B-mode ultrasound images optimized for well-lit environments. Originally introduced as Photopic (“Tageslichtsonographie”, Daylight sonography) by Siemens, this approach addresses the limitations of grayscale imaging under ambient light conditions. With the growing [...] Read more.
Daylight sonography refers to the technique of using color-tinted, brightness and contrast-controlled B-mode ultrasound images optimized for well-lit environments. Originally introduced as Photopic (“Tageslichtsonographie”, Daylight sonography) by Siemens, this approach addresses the limitations of grayscale imaging under ambient light conditions. With the growing emphasis on point-of-care ultrasound (POCUS) and mobile diagnostics, daylight-compatible imaging modes such as Photopic Mode have become increasingly relevant since they are performed under daylight conditions. This paper explores the technical background, visual physiology, clinical applications, implementation challenges, and future perspectives of daylight sonography, advocating for broader use and standardization. Standardization, further clinical validation, and integration with emerging technologies such as artificial intelligence (AI) are essential to fully realize the potential of daylight sonography in routine practice. Full article
(This article belongs to the Section Medical Research)
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22 pages, 330 KB  
Review
Passive AI Detection of Stress and Burnout Among Frontline Workers
by Rajib Rana, Niall Higgins, Terry Stedman, Sonja March, Daniel F. Gucciardi, Prabal D. Barua and Rohina Joshi
Nurs. Rep. 2025, 15(11), 373; https://doi.org/10.3390/nursrep15110373 - 22 Oct 2025
Viewed by 147
Abstract
Background: Burnout is a widespread concern across frontline professions, with healthcare, education, and emergency services workers experiencing particularly high rates of stress and emotional exhaustion. Passive artificial intelligence (AI) technologies may provide novel means to monitor and predict burnout risk using data [...] Read more.
Background: Burnout is a widespread concern across frontline professions, with healthcare, education, and emergency services workers experiencing particularly high rates of stress and emotional exhaustion. Passive artificial intelligence (AI) technologies may provide novel means to monitor and predict burnout risk using data collected continuously and non-invasively. Objective: This review aims to synthesize recent evidence on passive AI approaches for detecting stress and burnout among frontline workers, identify key physiological and behavioral biomarkers, and highlight current limitations in implementation, validation, and generalizability. Methods: A narrative review of peer-reviewed literature was conducted across multiple databases and digital libraries, including PubMed, IEEE Xplore, Scopus, ACM Digital Library, and Web of Science. Eligible studies applied passive AI methods to infer stress or burnout in individuals in frontline roles. Only studies using passive data (e.g., wearables, Electronic Health Record (EHR) logs) and involving healthcare, education, emergency response, or retail workers were included. Studies focusing exclusively on self-reported or active measures were excluded. Results: Recent evidence indicates that biometric data (e.g., heart rate variability, skin conductance, sleep) from wearables are most frequently used and moderately predictive of stress, with reported accuracies often ranging from 75 to 95%. Workflow interaction logs (e.g., EHR usage patterns) and communication metrics (e.g., email timing and sentiment) show promise but remain underexplored. Organizational network analysis and ambient computing remain largely conceptual in nature. Few studies have examined cross-sector or long-term data, and limited work addresses the generalizability of demographic or cultural findings. Challenges persist in data standardization, privacy, ethical oversight, and integration with clinical or operational workflows. Conclusions: Passive AI systems offer significant promise for proactive burnout detection among frontline workers. However, current studies are limited by small sample sizes, short durations, and sector-specific focus. Future work should prioritize longitudinal, multi-sector validation, address inclusivity and bias, and establish ethical frameworks to support deployment in real-world settings. Full article
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9 pages, 753 KB  
Article
Novel Tight Jensen’s Inequality-Based Performance Analysis of RIS-Aided Ambient Backscatter Communication Systems
by Kyuhyuk Chung
Electronics 2025, 14(20), 4099; https://doi.org/10.3390/electronics14204099 - 19 Oct 2025
Viewed by 166
Abstract
This paper presents a performance analysis of the reconfigurable intelligent surface (RIS)-aided ambient backscatter communication (AmBC) network. The system consists of a base station (BS), a backscatter device (BD), an RIS, and a destination (D). No direct link exists between the BS and [...] Read more.
This paper presents a performance analysis of the reconfigurable intelligent surface (RIS)-aided ambient backscatter communication (AmBC) network. The system consists of a base station (BS), a backscatter device (BD), an RIS, and a destination (D). No direct link exists between the BS and RIS and between the BD and D. We propose a novel tight Jensen’s inequality. A new tighter upper bound is derived for the ergodic capacity, and we demonstrate that the proposed upper bound is much tighter than the existing bound. Monte Carlo simulations are performed to validate the analytical results. The tightened upper bound is found to be almost identical to that in the Monte Carlo simulation results, and the ergodic capacity significantly increases with the number of reflecting elements. In addition, the ergodic capacity improves when the RIS is placed close to the BD or D, and when the distance between the BS and BD is small, the ergodic capacity is severely affected. Full article
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22 pages, 6104 KB  
Article
Real-Time Adaptive Nanofluid-Based Lubrication in Stainless Steel Turning Using an Intelligent Auto-Tuned MQL System
by Mahip Singh, Amit Rai Dixit, Anuj Kumar Sharma, Akash Nag and Sergej Hloch
Materials 2025, 18(20), 4714; https://doi.org/10.3390/ma18204714 - 14 Oct 2025
Viewed by 194
Abstract
Achieving optimal lubrication during machining processes, particularly turning of stainless steel, remains a significant challenge due to dynamic variations in cutting conditions that affect tool life, surface quality, and environmental impact. Conventional Minimum Quantity Lubrication (MQL) systems provide fixed flow rates and often [...] Read more.
Achieving optimal lubrication during machining processes, particularly turning of stainless steel, remains a significant challenge due to dynamic variations in cutting conditions that affect tool life, surface quality, and environmental impact. Conventional Minimum Quantity Lubrication (MQL) systems provide fixed flow rates and often fail to adapt to changing process parameters, limiting their effectiveness under fluctuating thermal and mechanical loads. To address these limitations, this study proposes an ambient-aware adaptive Auto-Tuned MQL (ATM) system that intelligently controls both nanofluid concentration and lubricant flow rate in real time. The system employs embedded sensors to monitor cutting zone temperature, surface roughness, and ambient conditions, linked through a feedback-driven control algorithm designed to optimize lubrication delivery dynamically. A Taguchi L9 design was used for experimental validation on AISI 304 stainless steel turning, investigating feed rate, cutting speed, and nanofluid concentration. Results demonstrate that the ATM system substantially improves machining outcomes, reducing surface roughness by more than 50% and cutting force by approximately 20% compared to conventional MQL. Regression models achieved high predictive accuracy, with R-squared values exceeding 99%, and surface analyses confirmed reduced adhesion and wear under adaptive lubrication. The proposed system offers a robust approach to enhancing machining performance and sustainability through intelligent, real-time lubrication control. Full article
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16 pages, 798 KB  
Article
Smart Spectrum Recommendation Approach with Edge Learning for 5G and Beyond Radio Planning
by Ahmet Yazar, Abdulkadir Sönmezışık, Metehan Doğan, Emre Kart and Ayşe Ayhan
Electronics 2025, 14(19), 3956; https://doi.org/10.3390/electronics14193956 - 8 Oct 2025
Viewed by 341
Abstract
Radio spectrum planning has become increasingly important, since the radio spectrum is a scarce resource. Moreover, the utilization of millimeter wave (mmWave) frequencies with fifth-generation (5G) standards has made radio planning more compelling. Considering their different strengths and weaknesses, it is essential to [...] Read more.
Radio spectrum planning has become increasingly important, since the radio spectrum is a scarce resource. Moreover, the utilization of millimeter wave (mmWave) frequencies with fifth-generation (5G) standards has made radio planning more compelling. Considering their different strengths and weaknesses, it is essential to know when mmWave frequencies should be selected in radio planning. In this paper, an approach with edge learning is developed to provide smart spectrum recommendations on which frequency bands should be used for a region. Using the proposed approach, radio spectrum planning can be carried out more efficiently, especially for the frequency ranges of mmWave communications. The proposed approach is designed with a distributed structure, based on awareness of the environment and ambient intelligence. This approach can be performed for each transmission point considering the environment information of the related coverage area. As a result, radio spectrum planning can be conducted for an entire region with the proposed system. The results show that this study both enhances overall user satisfaction and provides reasonable recommendations to operators in the transition to mmWave usage. Thus, the developed approach can be utilized for 5G and beyond communications. Specifically, this methodology is based on applying supervised ML algorithms to a synthetically generated dataset, and the best model achieves around 80% classification accuracy, demonstrating the feasibility of the approach. These quantitative results confirm its practicality and provide a concrete baseline for future studies. Full article
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22 pages, 558 KB  
Review
Smart Healthcare at Home: A Review of AI-Enabled Wearables and Diagnostics Through the Lens of the Pi-CON Methodology
by Steffen Baumann, Richard T. Stone and Esraa Abdelall
Sensors 2025, 25(19), 6067; https://doi.org/10.3390/s25196067 - 2 Oct 2025
Viewed by 918
Abstract
The rapid growth of AI-enabled medical wearables and home-based diagnostic devices has opened new pathways for preventive care, chronic disease management and user-driven health insights. Despite significant technological progress, many solutions face adoption hurdles, often due to usability challenges, episodic measurements and poor [...] Read more.
The rapid growth of AI-enabled medical wearables and home-based diagnostic devices has opened new pathways for preventive care, chronic disease management and user-driven health insights. Despite significant technological progress, many solutions face adoption hurdles, often due to usability challenges, episodic measurements and poor alignment with daily life. This review surveys the current landscape of at-home healthcare technologies, including wearable vital sign monitors, digital diagnostics and body composition assessment tools. We synthesize insights from the existing literature for this narrative review, highlighting strengths and limitations in sensing accuracy, user experience and integration into daily health routines. Special attention is given to the role of AI in enabling real-time insights, adaptive feedback and predictive monitoring across these devices. To examine persistent adoption challenges from a user-centered perspective, we reflect on the Pi-CON methodology, a conceptual framework previously introduced to stimulate discussion around passive, non-contact, and continuous data acquisition. While Pi-CON is highlighted as a representative methodology, recent external studies in multimodal sensing, RFID-based monitoring, and wearable–ambient integration confirm the broader feasibility of unobtrusive, passive, and continuous health monitoring in real-world environments. We conclude with strategic recommendations to guide the development of more accessible, intelligent and user-aligned smart healthcare solutions. Full article
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16 pages, 778 KB  
Article
A Framework for Evaluating the Reliability of Health Monitoring Technologies Based on Ambient Intelligence
by Mfundo Shakes Scott, Nobert Jere, Khulumani Sibanda and Ibomoiye Domor Mienye
Information 2025, 16(10), 833; https://doi.org/10.3390/info16100833 - 26 Sep 2025
Viewed by 322
Abstract
The reliability of health monitoring technologies has become increasingly critical as Ambient Intelligence (AmI) becomes integrated into healthcare. However, a significant gap remains in systematically evaluating reliability, particularly in resource-constrained environments. This study addresses this gap by introducing a comprehensive framework specifically designed [...] Read more.
The reliability of health monitoring technologies has become increasingly critical as Ambient Intelligence (AmI) becomes integrated into healthcare. However, a significant gap remains in systematically evaluating reliability, particularly in resource-constrained environments. This study addresses this gap by introducing a comprehensive framework specifically designed to evaluate the reliability of AmI-based health monitoring systems. The proposed framework combines robust simulation-based techniques, including reliability block diagrams (RBDs) and Monte Carlo Markov Chain (MCMC), to evaluate system robustness, data integrity, and adaptability. Validation was performed using real-world continuous glucose monitoring (CGM) and heart rate monitoring (HRM) systems in elderly care. The results demonstrate that the framework successfully identifies critical vulnerabilities, such as rapid initial system degradation and notable connectivity disruptions, and effectively guides targeted interventions that significantly enhance overall system reliability and user trust. The findings contribute actionable insights for practitioners, developers, and policymakers, laying a robust foundation for further advancements in explainable AI, proactive reliability management, and broader applications of AmI technologies in healthcare. Full article
(This article belongs to the Special Issue Artificial Intelligence and Data Science for Health, 2nd Edition)
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23 pages, 12353 KB  
Article
Cross-Media Infrared Measurement and Temperature Rise Characteristic Analysis of Coal Mine Electrical Equipment
by Xusheng Xue, Jianxin Yang, Hongkui Zhang, Yuan Tian, Qinghua Mao, Enqiao Zhang and Fandong Chen
Energies 2025, 18(19), 5122; https://doi.org/10.3390/en18195122 - 26 Sep 2025
Viewed by 368
Abstract
With the advancement of coal mine electrical equipment toward larger scale, higher complexity, and greater intelligence, traditional temperature rise monitoring methods have revealed critical limitations such as intrusive measurement, low spatial resolution, and delayed response. This study proposes a novel cross-media infrared measurement [...] Read more.
With the advancement of coal mine electrical equipment toward larger scale, higher complexity, and greater intelligence, traditional temperature rise monitoring methods have revealed critical limitations such as intrusive measurement, low spatial resolution, and delayed response. This study proposes a novel cross-media infrared measurement method combined with temperature rise characteristic analysis to overcome these challenges. First, a cross-media measurement principle is introduced, which uses the enclosure surface temperature as a proxy for the internal heat source temperature, thereby enabling non-invasive internal temperature rise measurement. Second, a non-contact, infrared thermography-based array-sensing measurement approach is adopted, facilitating the transition from traditional single-point temperature measurement to full-field thermal mapping with high spatial resolution. Furthermore, a multi-source data perception method is established by integrating infrared thermography with real-time operating current and ambient temperature, significantly enhancing the comprehensiveness and timeliness of thermal state monitoring. A hybrid prediction model combining Support Vector Regression (SVR) and Random Forest Regression (RFR) is developed, which effectively improves the prediction accuracy of the maximum internal temperature—particularly addressing the issue of weak surface temperature features during low heating stages. The experimental results demonstrate that the proposed method achieves high accuracy and stability across varying operating currents, with a root mean square error of 0.741 °C, a mean absolute error of 0.464 °C, and a mean absolute percentage error of 0.802%. This work provides an effective non-contact solution for real-time temperature rise monitoring and risk prevention in coal mine electrical equipment. Full article
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23 pages, 924 KB  
Article
Energy and Water Management in Smart Buildings Using Spiking Neural Networks: A Low-Power, Event-Driven Approach for Adaptive Control and Anomaly Detection
by Malek Alrashidi, Sami Mnasri, Maha Alqabli, Mansoor Alghamdi, Michael Short, Sean Williams, Nashwan Dawood, Ibrahim S. Alkhazi and Majed Abdullah Alrowaily
Energies 2025, 18(19), 5089; https://doi.org/10.3390/en18195089 - 24 Sep 2025
Viewed by 472
Abstract
The growing demand for energy efficiency and sustainability in smart buildings necessitates advanced AI-driven methods for adaptive control and predictive maintenance. This study explores the application of Spiking Neural Networks (SNNs) to event-driven processing, real-time anomaly detection, and edge computing-based optimization in building [...] Read more.
The growing demand for energy efficiency and sustainability in smart buildings necessitates advanced AI-driven methods for adaptive control and predictive maintenance. This study explores the application of Spiking Neural Networks (SNNs) to event-driven processing, real-time anomaly detection, and edge computing-based optimization in building automation. In contrast to conventional deep learning models, SNNs provide low-power, high-efficiency computation by mimicking biological neural processes, making them particularly suitable for real-time, edge-deployed decision-making. The proposed SNN based on Reward-Modulated Spike-Timing-Dependent Plasticity (STDP) and Bayesian Optimization (BO) integrates occupancy and ambient condition monitoring to dynamically manage assets such as appliances while simultaneously identifying anomalies for predictive maintenance. Experimental evaluations show that our BO-STDP-SNN framework achieves notable reductions in both energy consumption by 27.8% and power requirements by 70%, while delivering superior accuracy in anomaly detection compared with CNN, RNN, and LSTM based baselines. These results demonstrate the potential of SNNs to enhance the efficiency and resilience of smart building systems, reduce operational costs, and support long-term sustainability through low-latency, event-driven intelligence. Full article
(This article belongs to the Special Issue Digital Engineering for Future Smart Cities)
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17 pages, 11907 KB  
Article
Towards Health Status Determination and Local Weather Forecasts from Vitis vinifera Electrome
by Alessandro Chiolerio, Federico Taranto and Giuseppe Piero Brandino
Biomimetics 2025, 10(9), 636; https://doi.org/10.3390/biomimetics10090636 - 22 Sep 2025
Viewed by 511
Abstract
Recent advances in plant electrophysiology and machine learning suggest that bioelectric signals in plants may encode environmentally relevant information beyond physiological processes. In this study, we present a novel framework to analyse waveforms from real-time bioelectrical potentials recorded in vascular plants. Using a [...] Read more.
Recent advances in plant electrophysiology and machine learning suggest that bioelectric signals in plants may encode environmentally relevant information beyond physiological processes. In this study, we present a novel framework to analyse waveforms from real-time bioelectrical potentials recorded in vascular plants. Using a multi-channel electrophysiological monitoring system, we acquired continuous data from Vitis vinifera samples in a vineyard plantation under natural conditions. Plants were in different health conditions: healthy; under the infection of Flavescence dorée; plants in recovery from the same disease; and dead stumps. These signals were used as input features for an ensemble of complex machine learning models, including recurrent neural networks, trained to infer short-term meteorological parameters such as temperature and humidity. The models demonstrated predictive capabilities, with accuracy comparable to sensor-based benchmarks between one and two degree Celsius for temperature, particularly in forecasting rapid weather transitions. Feature importance analysis revealed plant-specific electrophysiological patterns that correlated with ambient conditions, suggesting the existence of biological pre-processing mechanisms sensitive to microclimatic fluctuations. This bioinspired approach opens new directions for developing plant-integrated environmental intelligence systems, offering passive and biologically rooted strategies for ultra-local forecasting—especially valuable in remote, sensor-sparse, or climate-sensitive regions. Our findings contribute to the emerging field of plant-based sensing and biomimetic environmental monitoring, expanding the role of flora to biosensors, useful in Earth system observation tasks. Full article
(This article belongs to the Section Bioinspired Sensorics, Information Processing and Control)
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17 pages, 8430 KB  
Article
Robust Audio–Visual Speaker Localization in Noisy Aircraft Cabins for Inflight Medical Assistance
by Qiwu Qin and Yian Zhu
Sensors 2025, 25(18), 5827; https://doi.org/10.3390/s25185827 - 18 Sep 2025
Viewed by 524
Abstract
Active Speaker Localization (ASL) involves identifying both who is speaking and where they are speaking from within audiovisual content. This capability is crucial in constrained and acoustically challenging environments, such as aircraft cabins during in-flight medical emergencies. In this paper, we propose a [...] Read more.
Active Speaker Localization (ASL) involves identifying both who is speaking and where they are speaking from within audiovisual content. This capability is crucial in constrained and acoustically challenging environments, such as aircraft cabins during in-flight medical emergencies. In this paper, we propose a novel end-to-end Cross-Modal Audio–Visual Fusion Network (CMAVFN) designed specifically for ASL under real-world aviation conditions, which are characterized by engine noise, dynamic lighting, occlusions from seats or oxygen masks, and frequent speaker turnover. Our model directly processes raw video frames and multi-channel ambient audio, eliminating the need for intermediate face detection pipelines. It anchors spatially resolved visual features with directional audio cues using a cross-modal attention mechanism. To enhance spatiotemporal reasoning, we introduce a dual-branch localization decoder and a cross-modal auxiliary supervision loss. Extensive experiments on public datasets (AVA-ActiveSpeaker, EasyCom) and our domain-specific AirCabin-ASL benchmark demonstrate that CMAVFN achieves robust speaker localization in noisy, occluded, and multi-speaker aviation scenarios. This framework offers a practical foundation for speech-driven interaction systems in aircraft cabins, enabling applications such as real-time crew assistance, voice-based medical documentation, and intelligent in-flight health monitoring. Full article
(This article belongs to the Special Issue Advanced Biomedical Imaging and Signal Processing)
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39 pages, 928 KB  
Review
Intelligence Architectures and Machine Learning Applications in Contemporary Spine Care
by Rahul Kumar, Conor Dougherty, Kyle Sporn, Akshay Khanna, Puja Ravi, Pranay Prabhakar and Nasif Zaman
Bioengineering 2025, 12(9), 967; https://doi.org/10.3390/bioengineering12090967 - 9 Sep 2025
Viewed by 1184
Abstract
The rapid evolution of artificial intelligence (AI) and machine learning (ML) technologies has initiated a paradigm shift in contemporary spine care. This narrative review synthesizes advances across imaging-based diagnostics, surgical planning, genomic risk stratification, and post-operative outcome prediction. We critically assess high-performing AI [...] Read more.
The rapid evolution of artificial intelligence (AI) and machine learning (ML) technologies has initiated a paradigm shift in contemporary spine care. This narrative review synthesizes advances across imaging-based diagnostics, surgical planning, genomic risk stratification, and post-operative outcome prediction. We critically assess high-performing AI tools, such as convolutional neural networks for vertebral fracture detection, robotic guidance platforms like Mazor X and ExcelsiusGPS, and deep learning-based morphometric analysis systems. In parallel, we examine the emergence of ambient clinical intelligence and precision pharmacogenomics as enablers of personalized spine care. Notably, genome-wide association studies (GWAS) and polygenic risk scores are enabling a shift from reactive to predictive management models in spine surgery. We also highlight multi-omics platforms and federated learning frameworks that support integrative, privacy-preserving analytics at scale. Despite these advances, challenges remain—including algorithmic opacity, regulatory fragmentation, data heterogeneity, and limited generalizability across populations and clinical settings. Through a multidimensional lens, this review outlines not only current capabilities but also future directions to ensure safe, equitable, and high-fidelity AI deployment in spine care delivery. Full article
(This article belongs to the Special Issue Artificial Intelligence and Machine Learning in Spine Research)
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22 pages, 9741 KB  
Article
Augminded: Ambient Mirror Display Notifications
by Timo Götzelmann, Pascal Karg and Mareike Müller
Multimodal Technol. Interact. 2025, 9(9), 93; https://doi.org/10.3390/mti9090093 - 4 Sep 2025
Viewed by 592
Abstract
This paper presents a new approach for providing contextual information in real-world environments. Our approach is consciously designed to be low-threshold; by using mirrors as augmented reality surfaces, no devices such as AR glasses or smartphones have to be worn or held by [...] Read more.
This paper presents a new approach for providing contextual information in real-world environments. Our approach is consciously designed to be low-threshold; by using mirrors as augmented reality surfaces, no devices such as AR glasses or smartphones have to be worn or held by the user. It enables technical and non-technical objects in the environment to be visually highlighted and thus subtly draw the attention of people passing by. The presented technology enables the provision of information that can be viewed in more detail by the user if required by slowing down their movement. Users can decide whether this is relevant to them or not. A prototype system was implemented and evaluated through a user study. The results show a high level of acceptance and intuitive usability of the system, with participants being able to reliably perceive and process the information displayed. The technology thus offers promising potential for the unobtrusive and context-sensitive provision of information in various application areas. The paper discusses limitations of the system and outlines future research directions to further optimize the technology and extend its applicability. Full article
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27 pages, 764 KB  
Article
Establishing a Digitally Enabled Healthcare Framework for Enhanced Prevention, Risk Identification, and Relief for Dementia and Frailty
by George Manias, Spiridon Likothanassis, Emmanouil Alexakis, Athos Antoniades, Camillo Marra, Guido Maria Giuffrè, Emily Charalambous, Dimitrios Tsolis, George Tsirogiannis, Dimitrios Koutsomitropoulos, Anastasios Giannaros, Dimitrios Tsoukalos, Kalliopi Klelia Lykothanasi, Paris Vogazianos, Spyridon Kleftakis, Dimitris Vrachnos, Konstantinos Charilaou, Jacopo Lenkowicz, Noemi Martellacci, Andrada Mihaela Tudor, Nemania Borovits, Mirella Sangiovanni, Willem-Jan van den Heuvel, on behalf of the COMFORTage Consortium and Dimosthenis Kyriazisadd Show full author list remove Hide full author list
J. Dement. Alzheimer's Dis. 2025, 2(3), 30; https://doi.org/10.3390/jdad2030030 - 1 Sep 2025
Viewed by 915
Abstract
During the last decade, artificial intelligence (AI) has enabled key technological innovations within the modern dementia and frailty healthcare and prevention landscape. This has boosted the impact of technology in the clinical setting, enabling earlier diagnosis with improved specificity and sensitivity, leading to [...] Read more.
During the last decade, artificial intelligence (AI) has enabled key technological innovations within the modern dementia and frailty healthcare and prevention landscape. This has boosted the impact of technology in the clinical setting, enabling earlier diagnosis with improved specificity and sensitivity, leading to accurate and time-efficient support that has driven the development of preventative interventions minimizing the risk and rate of progression. Background/Objectives: The rapid ageing of the European population places a substantial strain on the current healthcare system and imposes several challenges. COMFORTage is the joint effort of medical experts (i.e., neurologists, psychiatrists, neuropsychologists, nurses, and memory clinics), social scientists and humanists, technical experts (i.e., data scientists, AI experts, and robotic experts), digital innovation hubs (DIHs), and living labs (LLs) to establish a pan-European framework for community-based, integrated, and people-centric prevention, monitoring, and progression-managing solutions for dementia and frailty. Its main goal is to introduce an integrated and digitally enabled framework that will facilitate the provision of personalized and integrated care prevention and intervention strategies on dementia and frailty, by piloting novel technologies and producing quantified evidence on the impact to individuals’ wellbeing and quality of life. Methods: A robust and comprehensive design approach adopted through this framework provides the guidelines, tools, and methodologies necessary to empower stakeholders by enhancing their health and digital literacy. The integration of the initial information from 13 pilots across 8 European countries demonstrates the scalability and adaptability of this approach across diverse healthcare systems. Through a systematic analysis, it aims to streamline healthcare processes, reduce health inequalities in modern communities, and foster healthy and active ageing by leveraging evidence-based insights and real-world implementations across multiple regions. Results: Emerging technologies are integrated with societal and clinical innovations, as well as with advanced and evidence-based care models, toward the introduction of a comprehensive global coordination framework that: (a) improves individuals’ adherence to risk mitigation and prevention strategies; (b) delivers targeted and personalized recommendations; (c) supports societal, lifestyle, and behavioral changes; (d) empowers individuals toward their health and digital literacy; and (e) fosters inclusiveness and promotes equality of access to health and care services. Conclusions: The proposed framework is designed to enable earlier diagnosis and improved prognosis coupled with personalized prevention interventions. It capitalizes on the integration of technical, clinical, and social innovations and is deployed in 13 real-world pilots to empirically assess its potential impact, ensuring robust validation across diverse healthcare settings. Full article
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40 pages, 1946 KB  
Review
Climate-Resilient Crops: Integrating AI, Multi-Omics, and Advanced Phenotyping to Address Global Agricultural and Societal Challenges
by Doni Thingujam, Sandeep Gouli, Sachin Promodh Cooray, Katie Busch Chandran, Seth Bradley Givens, Renganathan Vellaichamy Gandhimeyyan, Zhengzhi Tan, Yiqing Wang, Keerthi Patam, Sydney A. Greer, Ranju Acharya, David Octor Moseley, Nesma Osman, Xin Zhang, Megan E. Brooker, Mary Love Tagert, Mark J. Schafer, Changyoon Jeong, Kevin Flynn Hoffseth, Raju Bheemanahalli, J. Michael Wyss, Nuwan Kumara Wijewardane, Jong Hyun Ham and M. Shahid Mukhtaradd Show full author list remove Hide full author list
Plants 2025, 14(17), 2699; https://doi.org/10.3390/plants14172699 - 29 Aug 2025
Viewed by 2571
Abstract
Drought and excess ambient temperature intensify abiotic and biotic stresses on agriculture, threatening food security and economic stability. The development of climate-resilient crops is crucial for sustainable, efficient farming. This review highlights the role of multi-omics encompassing genomics, transcriptomics, proteomics, metabolomics, and epigenomics [...] Read more.
Drought and excess ambient temperature intensify abiotic and biotic stresses on agriculture, threatening food security and economic stability. The development of climate-resilient crops is crucial for sustainable, efficient farming. This review highlights the role of multi-omics encompassing genomics, transcriptomics, proteomics, metabolomics, and epigenomics in identifying genetic pathways for stress resilience. Advanced phenomics, using drones and hyperspectral imaging, can accelerate breeding programs by enabling high-throughput trait monitoring. Artificial intelligence (AI) and machine learning (ML) enhance these efforts by analyzing large-scale omics and phenotypic data, predicting stress tolerance traits, and optimizing breeding strategies. Additionally, plant-associated microbiomes contribute to stress tolerance and soil health through bioinoculants and synthetic microbial communities. Beyond agriculture, these advancements have broad societal, economic, and educational impacts. Climate-resilient crops can enhance food security, reduce hunger, and support vulnerable regions. AI-driven tools and precision agriculture empower farmers, improving livelihoods and equitable technology access. Educating teachers, students, and future generations fosters awareness and equips them to address climate challenges. Economically, these innovations reduce financial risks, stabilize markets, and promote long-term agricultural sustainability. These cutting-edge approaches can transform agriculture by integrating AI, multi-omics, and advanced phenotyping, ensuring a resilient and sustainable global food system amid climate change. Full article
(This article belongs to the Section Crop Physiology and Crop Production)
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