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  • Review
  • Open Access
16 Citations
6,266 Views
21 Pages

Advances in Wearable Chemosensors

  • Panagiota Koralli and
  • Dionysios E. Mouzakis

In this review, the latest research on wearable chemosensors is presented. In focus are the results from open literature, mainly from the last three years. The progress in wearable chemosensors is presented with attention drawn to the measuring techn...

(This article belongs to the Special Issue Chemical and Biosensors: A Theme Issue in Honor of Professor Otto S. Wolfbeis)
  • Review
  • Open Access
32 Citations
7,261 Views
24 Pages

19 February 2023

Molecularly imprinted polymer (MIP)-based luminescent chemosensors combine the advantages of the highly specific molecular recognition of the imprinting sites and the high sensitivity with the luminescence detection. These advantages have drawn great...

(This article belongs to the Special Issue Activatable Probes for Biosensing, Imaging, and Photomedicine)
  • Review
  • Open Access
411 Views
61 Pages

Pyrazine-Based Chemosensors for Cation Detection

  • Tatyana N. Moshkina,
  • Emiliya V. Nosova and
  • Galina N. Lipunova

8 October 2026

Pyrazine (1,4-diazine) and its annulated derivatives are promising platforms for colorimetric and fluorescent chemosensors of biologically and environmentally relevant metal cations, including Hg2+, Cu2+, Zn2+, Pb2+, Fe3+, Al3+, Co2+, Ni2+, Ag+ and C...

(This article belongs to the Special Issue Featured Reviews in Organic Chemistry 2026–2027)
  • Article
  • Open Access
16 Citations
6,550 Views
14 Pages

5 September 2012

The interactions between chemosensors, 3-amino-5-(4,5,6,7-tetrahydro-1H-indol-2-yl)isoxazole-4-carboxamide (AIC) derivatives, and different anions (F− Cl−, Br−, AcO−, and H2PO4−) have been theoretically investigated using DFT approaches. It turned ou...

(This article belongs to the Section Physical Chemistry, Theoretical and Computational Chemistry)
  • Review
  • Open Access
85 Citations
10,164 Views
59 Pages

Recent Developments in Rhodamine-Based Chemosensors: A Review of the Years 2018–2022

  • Yujiao Wang,
  • Xiaojun Wang,
  • Wenyu Ma,
  • Runhua Lu and ,
  • Wenfeng Zhou and
  • Haixiang Gao
  • + 1 author+ 0 author

Chemosensors based on traditional fluorescent dyes have always contributed to the development of chemical sensor areas. In this review, the rhodamine-based chemosensors’ improvements and applications from 2018 to 2022 are discussed, mainly focu...

(This article belongs to the Special Issue Chemosensors for Ion Detection)
  • Review
  • Open Access
142 Citations
25,045 Views
26 Pages

Fluorescent Chemosensors for Toxic Organophosphorus Pesticides: A Review

  • Sherine O. Obare,
  • Chandrima De,
  • Wen Guo,
  • Tajay L. Haywood and ,
  • Tova A. Samuels,
  • Clara P. Adams,
  • Noah O. Masika,
  • Desmond H. Murray,
  • Ginger A. Anderson and
  • Kenneth Fletcher
  • + 6 authors+ 1 author

21 July 2010

Many organophosphorus (OP) based compounds are highly toxic and powerful inhibitors of cholinesterases that generate serious environmental and human health concerns. Organothiophosphates with a thiophosphoryl (P=S) functional group constitute a broad...

(This article belongs to the Special Issue Fluorescent Chemosensors)
  • Article
  • Open Access
5 Citations
3,301 Views
13 Pages

Chemosensors have attracted considerable attention among the numerous strategies for detecting organic molecules in water. A turn-off mechanism was previously employed for the construction of a cyclodextrin (CD) chemosensor. This mechanism is greatly...

(This article belongs to the Special Issue Chromogenic and Fluorogenic Chemosensors)
  • Review
  • Open Access
29 Citations
4,734 Views
31 Pages

Advances in Cost-Effective Chemosensors for Sustainable Monitoring in Food Safety and Processing

  • Camelia Albu,
  • Ana Chira,
  • Gabriel-Lucian Radu and
  • Sandra A. V. Eremia

Cost-effective chemosensors have become an indispensable tool for sustainable monitoring in food safety and processing, where there is an urgent need for affordable, efficient, and real-time analytical solutions. This review discusses recent advances...

(This article belongs to the Special Issue Low-Cost Chemosensors for Applications in Environment, Health, Food, and Industry Process Control)
  • Review
  • Open Access
141 Citations
21,739 Views
26 Pages

Application of PEDOT:PSS and Its Composites in Electrochemical and Electronic Chemosensors

  • Nan Gao,
  • Jiarui Yu,
  • Qingyun Tian,
  • Jiangfan Shi and ,
  • Miao Zhang,
  • Shuai Chen and
  • Ling Zang
  • + 2 authors+ 0 author

Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) is a highly important and attractive conducting polymer as well as commercially available in organic electronics, including electrochemical and electronic chemosensors, due to its uni...

(This article belongs to the Special Issue Chemical and Biosensors: A Theme Issue in Honor of Professor Otto S. Wolfbeis)
  • Article
  • Open Access
10 Citations
4,062 Views
13 Pages

Phthalocyanine-Functionalized Magnetic Silica Nanoparticles as Anion Chemosensors

  • João M. M. Rodrigues,
  • Andreia S. F. Farinha,
  • Zhi Lin,
  • José A. S. Cavaleiro and ,
  • Augusto C. Tome and
  • Joao P. C. Tome
  • + 1 author+ 0 author

26 February 2021

Anionic species are one of the most common pollutants in residual and freshwaters. The presence of anthropogenic anions in water drastically increases the toxicity to living beings. Here, we report the preparation of a new optical active material bas...

(This article belongs to the Collection Optical Chemical Sensors: Design and Applications)
  • Review
  • Open Access
18 Citations
5,923 Views
28 Pages

Chemosensors for H2O2 Detection: Principles, Active Materials, and Applications

  • Meng Zhou,
  • Hui Sun,
  • Shuai Chen,
  • Mingna Yang and ,
  • Rongqing Dong,
  • Xiaomei Yang and
  • Ling Zang
  • + 2 authors+ 0 author

Hydrogen peroxide (H2O2), a common oxidant present in the environment, food, and biological systems, has wide-ranging applications. While H2O2 is generally considered non-toxic, prolonged or repeated exposure to high concentrations can be harmful, ma...

(This article belongs to the Section Materials for Chemical Sensing)
  • Article
  • Open Access
7 Citations
3,615 Views
15 Pages

Pt(dithiolene)-Based Colorimetric Chemosensors for Multiple Metal-Ion Sensing

  • Heawon Son,
  • Seohyeon Jang,
  • Gayoung Lim,
  • Taeyong Kim and ,
  • Inho Nam and
  • Dong-Youn Noh
  • + 1 author+ 0 author

21 July 2021

Colorimetric chemosensors are widely employed for in-field analysis to detect transition metal ions in real-time with the naked eye. Colorimetric chemosensors have attracted considerable attention because they can conveniently provide quantitative an...

(This article belongs to the Section Sustainable Materials)
  • Review
  • Open Access
23 Citations
5,655 Views
26 Pages

Perylene Imide-Based Optical Chemosensors for Vapor Detection

  • Miao Zhang,
  • Jiangfan Shi,
  • Chenglong Liao,
  • Qingyun Tian and ,
  • Chuanyi Wang,
  • Shuai Chen and
  • Ling Zang
  • + 2 authors+ 0 author

Perylene imide (PI) molecules and materials have been extensively studied for optical chemical sensors, particularly those based on fluorescence and colorimetric mode, taking advantage of the unique features of PIs such as structure tunability, good...

(This article belongs to the Special Issue Organic Fluorescent Materials as Chemical Sensors)
  • Review
  • Open Access
3 Citations
920 Views
21 Pages

Mushroom-Derived Hydrophobins for Antifouling and Interface Preservation in Chemosensors

  • Nardos F. Bisrat,
  • Bethany R. Finnefrock,
  • Matthew D. Gacura,
  • Longyan Chen and
  • Davide Piovesan

5 March 2026

Surface fouling remains a critical challenge for medical devices and chemosensor systems operating in biological environments, where nonspecific adsorption of proteins, cells, and microorganisms can lead to signal drift, reduced sensitivity, and shor...

(This article belongs to the Special Issue Low-Cost Chemosensors for Applications in Environment, Health, Food, and Industry Process Control, 2nd Edition)
  • Review
  • Open Access
18 Citations
4,390 Views
18 Pages

Rational Design of Fluorescent/Colorimetric Chemosensors for Detecting Transition Metal Ions by Varying Functional Groups

  • Jong-Kwon Park,
  • Junhyeop Shin,
  • Seohyeon Jang,
  • Myeong-Lok Seol and ,
  • Jihyeon Kang,
  • Seyoung Choi,
  • Hojong Eom,
  • Ohhyun Kwon,
  • Soomin Park and
  • Inho Nam
  • + 6 authors+ 1 author

29 October 2022

In recent decades, concerns about increasing biological and environmental contamination have necessitated the development of chemosensors with high selectivity, sensitivity, and cost-effectiveness. In principle, the sensing performance can be affecte...

(This article belongs to the Section Inorganic Materials)
  • Article
  • Open Access
11 Citations
3,889 Views
14 Pages

Development of Fluorescent Chemosensors for Calcium and Lead Detection

  • Liliana J. Gomes,
  • Mani Outis,
  • Clara S. B. Gomes,
  • Augusto C. Tomé and
  • Artur J. Moro

21 January 2024

In the present work, several coumarin-3-carboxamides with different azacrown ether moieties were designed and tested as potential luminescent sensors for metal ions. The derivative containing a 1-aza-15-crown-5 as a metal chelating group was found to...

  • Review
  • Open Access
24 Citations
5,286 Views
31 Pages

Detection of Selected Heavy Metal Ions Using Organic Chromofluorescent Chemosensors

  • Samina Aslam,
  • Iram Kousar,
  • Sadia Rani,
  • Wajiha Altaf and ,
  • Sadia Bristy and
  • Rachid Skouta
  • + 1 author+ 0 author

25 March 2025

Heavy and transition metal (HTM) ions have significant harmful effects on the physical environment and play crucial roles in biological systems; hence, it is crucial to accurately identify and quantify any trace pollution. Molecular sensors which are...

(This article belongs to the Section Cross-Field Chemistry)
  • Review
  • Open Access
77 Citations
9,757 Views
42 Pages

6 October 2023

Toxic cations, including heavy metals, pose significant environmental and health risks, necessitating the development of reliable detection methods. This review investigates the techniques and approaches used to strengthen the sensitivity and selecti...

(This article belongs to the Special Issue Feature Papers in Photochemistry and Photocatalysis)
  • Review
  • Open Access
43 Citations
7,703 Views
20 Pages

24 May 2016

The contaminations of Fusarium mycotoxins in grains and related products, and the exposure in human body are considerable concerns in food safety and human health worldwide. The common Fusarium mycotoxins include fumonisins, T-2 toxin, deoxynivalenol...

(This article belongs to the Collection Biorecognition Assays for Mycotoxins)
  • Review
  • Open Access
60 Citations
8,385 Views
31 Pages

Recent Advances in Electrochemical Chitosan-Based Chemosensors and Biosensors: Applications in Food Safety

  • Rita Petrucci,
  • Mauro Pasquali,
  • Francesca Anna Scaramuzzo and
  • Antonella Curulli

Chitosan is a biopolymer derived from chitin. It is a non-toxic, biocompatible, bioactive, and biodegradable polymer. Due to its properties, chitosan has found applications in several and different fields such as agriculture, food industry, medicine,...

(This article belongs to the Section Electrochemical Devices and Sensors)
  • Review
  • Open Access
20 Citations
5,237 Views
24 Pages

The precise control and monitoring of pH values remain critical for many chemical, physiological and biological processes. Perylene diimide (PDI)-based molecules and materials exhibit excellent thermal, chemical and photochemical stability, unique UV...

(This article belongs to the Special Issue Chemosensors for Ion Detection)
  • Proceeding Paper
  • Open Access
1,974 Views
5 Pages

Crown Ether Benzoxazolyl-Alanines as Fluorimetric Chemosensors for the Detection of Palladium in Aqueous Environment

  • Cátia D. F. Martins,
  • Patrícia M. R. Batista,
  • M. Manuela M. Raposo and
  • Susana P. G. Costa

14 November 2020

Palladium has wide application in different contexts and, as a consequence, high levels of palladium in the environment have been reported, representing a risk to human health. Considering the interest to develop more selective and sensitive chemose...

(This article belongs to the Proceedings of The 24th International Electronic Conference on Synthetic Organic Chemistry)
  • Article
  • Open Access
9 Citations
3,073 Views
10 Pages

19 March 2020

Hg2+ ions can accumulate in the natural environment and in organisms, where they cause damage to the central nervous system. Therefore, the detection of Hg2+ ions is essential for monitoring environmental contamination and human health. Herein, we de...

(This article belongs to the Special Issue Application of Nanoparticles as Biosensors in the Biomedical Field)
  • Review
  • Open Access
15 Citations
5,405 Views
25 Pages

Resistive Chemosensors for the Detection of CO Based on Conducting Polymers and Carbon Nanocomposites: A Review

  • Mihaela Savin,
  • Carmen-Marinela Mihailescu,
  • Carmen Moldovan,
  • Alexandru Grigoroiu and ,
  • Ion Ion and
  • Alina Catrinel Ion
  • + 1 author+ 0 author

26 January 2022

Nanocomposite materials have seen increased adoption in a wide range of applications, with toxic gas detection, such as carbon monoxide (CO), being of particular interest for this review. Such sensors are usually characterized by the presence of CO a...

(This article belongs to the Special Issue Electrochemical Applications of Carbon-Based Nanomaterials)
  • Article
  • Open Access
46 Citations
24,025 Views
16 Pages

Development of a Low-Cost UV-Vis Spectrophotometer and Its Application for the Detection of Mercuric Ions Assisted by Chemosensors

  • David González-Morales,
  • Asmilly Valencia,
  • Astrid Díaz-Nuñez,
  • Marcial Fuentes-Estrada and ,
  • Oswaldo López-Santos and
  • Olimpo García-Beltrán
  • + 1 author+ 0 author

8 February 2020

Detection of an environmental contaminant requires the use of expensive measurement equipment, which limits the realization of in situ tests because of their high cost, their limited portability, or the extended time duration of the tests. This paper...

(This article belongs to the Section Optical Sensors)
  • Review
  • Open Access
22 Citations
8,707 Views
23 Pages

Macrocycles play a crucial role in supramolecular chemistry and the family of macrocyclic arenes represents one of the most important types of hosts. Among them, calixarenes, resorcinarenes and pillararenes are the most commonly encountered macrocycl...

(This article belongs to the Special Issue Organic Fluorescent Materials as Chemical Sensors)
  • Proceeding Paper
  • Open Access
1 Citations
4,465 Views
6 Pages

Heterocyclic Aldehydes Based on Thieno[3,2-b]thiophene Core: Synthesis and Preliminary Studies as Ion Optical Chemosensors

  • Rui P. C. L. Sousa,
  • Raquel C. R. Gonçalves,
  • Susana P. G. Costa,
  • Rita B. Figueira and
  • Maria Manuela M. Raposo

13 November 2020

Heterocyclic aldehydes show a variety of optical properties and the versatility of their reactivity allows them to yield a wide range of more complex compounds, with application in areas such as medicinal, materials and supramolecular chemistry. The...

(This article belongs to the Proceedings of The 24th International Electronic Conference on Synthetic Organic Chemistry)
  • Article
  • Open Access
4,821 Views
40 Pages

Design and Synthesis of Arylboronic Acid Chemosensors for the Fluorescent-Thin Layer Chromatography (f-TLC) Detection of Mycolactone

  • Gideon Atinga Akolgo,
  • Benjamin M. Partridge,
  • Timothy D. Craggs,
  • Kingsley Bampoe Asiedu and
  • Richard Kwamla Amewu

Fluorescent chemosensors are increasingly becoming relevant in recognition chemistry due to their sensitivity, selectivity, fast response time, real-time detection capability, and low cost. Boronic acids have been reported for the recognition of myco...

(This article belongs to the Special Issue Advanced Colorimetric and Fluorescent Sensors and Their Application in Detection, 2nd Edition)
  • Article
  • Open Access
14 Citations
9,873 Views
12 Pages

Detection Papers with Chromogenic Chemosensors for Direct Visual Detection and Distinction of Liquid Chemical Warfare Agents

  • Vladimír Pitschmann,
  • Lukáš Matějovský,
  • Kamila Lunerová,
  • Michal Dymák and ,
  • Martin Urban and
  • Lukáš Králík
  • + 1 author+ 0 author

This work provides a summary of our results in the area of the experimental development of detection paper for the detection of liquid phase chemical warfare agents (drops, aerosol), the presence of which is demonstrated by the development of charact...

(This article belongs to the Special Issue Chromogenic and Fluorogenic Chemosensors)
  • Review
  • Open Access
98 Citations
11,517 Views
42 Pages

Recent Advances in Aggregation-Induced Emission Chemosensors for Anion Sensing

  • Ming Hui Chua,
  • Kwok Wei Shah,
  • Hui Zhou and
  • Jianwei Xu

25 July 2019

The discovery of the aggregation-induced emission (AIE) phenomenon in the early 2000s not only has overcome persistent challenges caused by traditional aggregation-caused quenching (ACQ), but also has brought about new opportunities for the developme...

(This article belongs to the Special Issue Aggregation-Induced Emission: Materials and Applications)
  • Article
  • Open Access
10 Citations
2,533 Views
15 Pages

25 October 2023

Bearing in mind the interest in the development and application of amino acids/peptides as bioinspired systems for sensing, a series of new phenylalanine derivatives bearing thiosemicarbazone and hydrazone units at the side chain were synthesised and...

(This article belongs to the Special Issue ECSOC-26)
  • Review
  • Open Access
68 Citations
7,300 Views
30 Pages

26 October 2022

Taking advantage of high porosity, large surface area, tunable nanostructures and ease of functionalization, metal-organic frameworks (MOFs) have been popularly applied in different fields, including adsorption and separation, heterogeneous catalysis...

(This article belongs to the Special Issue Electrochemical and Fluorescent Biosensors: Novel Strategies, Methods, and Materials)
  • Review
  • Open Access
562 Views
28 Pages

Application of Nano-Bio/Chemosensors for Pharmaceutical Residue Detection and Removal During Wastewater Treatment

  • Eleftheria K. Tsoutsa,
  • Dimitra K. Toubanaki,
  • Sophie Mavrikou,
  • Victoria Samanidou and
  • Athanasia K. Tolkou

19 August 2026

The increasing accumulation of pharmaceutical residues in water environments poses serious threats concerning environmental safety and public health, mainly due to their tenacity, continuous bio-activity, and resistance to traditional wastewater trea...

(This article belongs to the Special Issue Feature Review Papers in Environmental Chemistry and Sustainability)
  • Article
  • Open Access
38 Citations
5,330 Views
19 Pages

Naked-Eye Detection of Morphine by Au@Ag Nanoparticles-Based Colorimetric Chemosensors

  • Tahereh Rohani Bastami,
  • Mansour Bayat and
  • Roberto Paolesse

7 March 2022

In this study, we report a novel and facile colorimetric assay based on silver citrate-coated Au@Ag nanoparticles (Au@AgNPs) as a chemosensor for the naked-eye detection of morphine (MOR). The developed optical sensing approach relied on the aggregat...

(This article belongs to the Collection Optical Chemical Sensors: Design and Applications)
  • Review
  • Open Access
1 Citations
2,806 Views
20 Pages

The necessity for complex functionality materials is increasing due to the emergence of high-tech technologies and the deepening needs of B-to-B companies in the industry. Study on advanced multifunctional materials is also increasing due to interest...

(This article belongs to the Section Nanostructures for Chemical Sensing)
  • Article
  • Open Access
2 Citations
3,483 Views
15 Pages

Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore

  • Martin Urban,
  • Tomáš Dropa,
  • Markéta Zelenková,
  • Michal Dymák and
  • Vladimír Pitschmann

This paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A, im...

(This article belongs to the Section Applied Chemical Sensors)
  • Article
  • Open Access
12 Citations
5,767 Views
11 Pages

6 November 2015

The synthesis of four symmetrical compounds containing urea/thiourea and anthracene/nitrobenzene groups was optimized. N,N’-Di((anthracen-9-yl)-methylene) thio-carbonohydrazide showed sensitive and selective binding ability for acetate ion among the...

(This article belongs to the Section Chemical Sensors)
  • Article
  • Open Access
2,502 Views
19 Pages

Coordination Chemistry of Mixed-Donor Pyridine-Containing Macrocyclic Ligands: From Optical to Redox Chemosensors for Heavy Metal Ions

  • Alessandra Garau,
  • Alexander J. Blake,
  • Maria Carla Aragoni,
  • Massimiliano Arca and ,
  • Claudia Caltagirone,
  • Francesco Demartin,
  • Vito Lippolis,
  • Giacomo Picci and
  • Enrico Podda
  • + 4 authors+ 0 author

31 December 2024

2,8-Dithia-5-aza-2,6-pyridinophane (L1) has been used as a receptor unit in the construction of the conjugated redox chemosensor 5-ferrocenylmethyl-2,8-dithia-5-aza-2,6-pyridinophane (L3). In order to further explore the coordination chemistry of L1,...

(This article belongs to the Special Issue Exclusive Contributions by the Editorial Board Members (EBMs) of the Inorganic Chemistry Section of Molecules 2024)
  • Article
  • Open Access
2 Citations
2,236 Views
16 Pages

In recent years, in the field of bioanalysis, the use of saliva as a biological fluid for the determination of biomarkers has been proposed. Saliva analysis stands out for its simplicity and non-invasive sampling. This paper proposes a method for the...

(This article belongs to the Collection Recent Advances in Multifunctional Sensing Technology for Gas Analysis)
  • Article
  • Open Access
14 Citations
7,544 Views
12 Pages

A Rationally Designed, Spiropyran-Based Chemosensor for Magnesium

  • Georgina M. Sylvia,
  • Adrian M. Mak,
  • Sabrina Heng,
  • Akash Bachhuka and ,
  • Heike Ebendorff-Heidepriem and
  • Andrew D. Abell
  • + 1 author+ 0 author

Magnesium ions (Mg2+) play an important role in mammalian cell function; however, relatively little is known about the mechanisms of Mg2+ regulation in disease states. An advance in this field would come from the development of selective, reversible...

(This article belongs to the Special Issue Fluorescent Probes for Live Cell Imaging)
  • Review
  • Open Access
76 Citations
15,828 Views
47 Pages

A Review on Bio- and Chemosensors for the Detection of Biogenic Amines in Food Safety Applications: The Status in 2022

  • Stella Givanoudi,
  • Marc Heyndrickx,
  • Tom Depuydt,
  • Mehran Khorshid and ,
  • Johan Robbens and
  • Patrick Wagner
  • + 1 author+ 0 author

5 January 2023

This article provides an overview on the broad topic of biogenic amines (BAs) that are a persistent concern in the context of food quality and safety. They emerge mainly from the decomposition of amino acids in protein-rich food due to enzymes excret...

(This article belongs to the Section Chemical Sensors)
  • Review
  • Open Access
8 Citations
4,303 Views
34 Pages

Wearable Chemosensors in Physiological Monitoring

  • Zeyi Tang,
  • Tianrui Cui,
  • Houfang Liu,
  • Jinming Jian and ,
  • Ding Li,
  • Yi Yang and
  • Tianling Ren
  • + 2 authors+ 0 author

The development of flexible electronic technology has led to significant advancements in wearable sensors. In the past decades, wearable chemosensors have received much attention from researchers worldwide due to their high portability, flexibility,...

(This article belongs to the Special Issue Chemosensors in Biological Challenges, Volume II)

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