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95 Results Found

  • Article
  • Open Access
8 Citations
4,423 Views
18 Pages

Activation of Drosophila melanogaster TRPA1 Isoforms by Citronellal and Menthol

  • Brett Boonen,
  • Justyna B. Startek,
  • Alina Milici,
  • Alejandro López-Requena,
  • Melissa Beelen,
  • Patrick Callaerts and
  • Karel Talavera

12 October 2021

Background: The transient receptor potential ankyrin 1 (TRPA1) cation channels function as broadly-tuned sensors of noxious chemicals in many species. Recent studies identified four functional TRPA1 isoforms in Drosophila melanogaster (dTRPA1(A) to (...

  • Feature Paper
  • Article
  • Open Access
20 Citations
5,741 Views
10 Pages

Brønsted and Lewis Solid Acid Catalysts in the Valorization of Citronellal

  • Federica Zaccheria,
  • Federica Santoro,
  • Elvina Dhiaul Iftitah and
  • Nicoletta Ravasio

22 September 2018

Terpenes are valuable starting materials for the synthesis of molecules that are of interest to the flavor, fragrance, and pharmaceutical industries. However, most processes involve the use of mineral acids or homogeneous Lewis acid catalysts. Here,...

  • Article
  • Open Access
23 Citations
3,149 Views
20 Pages

Natural Product Citronellal can Significantly Disturb Chitin Synthesis and Cell Wall Integrity in Magnaporthe oryzae

  • Ai-Ai Zhou,
  • Rong-Yu Li,
  • Fei-Xu Mo,
  • Yi Ding,
  • Ruo-Tong Li,
  • Xue Guo,
  • Ke Hu and
  • Ming Li

16 December 2022

Background: Natural products are often favored in the study of crop pests and diseases. Previous studies have shown that citronellal has a strong inhibition effect on Magnaporthe oryzae. The objective of this study was to clarify its mechanism of act...

  • Article
  • Open Access
3 Citations
2,463 Views
11 Pages

3 December 2024

This study aimed to analyze the potential of phytochemicals linalool and citronellal against E. coli and S. aureus biofilms and to compare the results to sodium hypochlorite. We tested the minimal inhibitory concentration, bacterial cell reduction, r...

  • Article
  • Open Access
12 Citations
5,437 Views
10 Pages

Synthesis, Antimicrobial, and Antioxidant Activities of Chalcogen-Containing Nitrone Derivatives from (R)-citronellal

  • Mariana C. Ferraz,
  • Renata A. Mano,
  • Daniela H. Oliveira,
  • Darla S. V. Maia,
  • Wladimir P. Silva,
  • Lucielli Savegnago,
  • Eder J. Lenardão and
  • Raquel G. Jacob

Background: The main constituents of Cymbopogonnardus (L) Rendle and C. citratus (DC) Stapfessential oils are (R)-citronellal and citral, respectively. Organochalcogen compounds can boost the biological activities of natural products. Methods: Severa...

  • Article
  • Open Access
44 Citations
7,514 Views
17 Pages

18 December 2020

Triple negative breast cancer is one of the most aggressive breast cancer type with abilities of early metastasis and chemoresistance. The tropical plant Citrus hystrix DC. has been reported to promote many biological activities including anticancer....

  • Article
  • Open Access
21 Citations
6,428 Views
15 Pages

Engineering the Enantioselectivity of Yeast Old Yellow Enzyme OYE2y in Asymmetric Reduction of (E/Z)-Citral to (R)-Citronellal

  • Xiangxian Ying,
  • Shihua Yu,
  • Meijuan Huang,
  • Ran Wei,
  • Shumin Meng,
  • Feng Cheng,
  • Meilan Yu,
  • Meirong Ying,
  • Man Zhao and
  • Zhao Wang

18 March 2019

The members of the Old Yellow Enzyme (OYE) family are capable of catalyzing the asymmetric reduction of (E/Z)-citral to (R)-citronellal—a key intermediate in the synthesis of L-menthol. The applications of OYE-mediated biotransformation are usu...

  • Article
  • Open Access
17 Citations
3,503 Views
22 Pages

Citronellal as a Promising Candidate for Alzheimer’s Disease Treatment: A Comprehensive Study on In Silico and In Vivo Anti-Acetylcholine Esterase Activity

  • Pavani K,
  • D S. N. B. K. Prasanth,
  • Murthy K. R. Shadakshara,
  • Sheikh F. Ahmad,
  • Ramanjaneyulu Seemaladinne,
  • Mithun Rudrapal and
  • Praveen Kumar Pasala

4 November 2023

One of the primary therapeutic approaches for managing Alzheimer’s disease (AD) involves the modulation of Acetylcholine esterase (AChE) activity to elevate acetylcholine (ACh) levels inside the brain. The current study employed computational c...

  • Article
  • Open Access
18 Citations
6,099 Views
12 Pages

2 February 2018

The development of a biotechnological method for the production of new biologically active phosphatidylcholine containing monoterpene citronellic acid (CA) was the aim of this work. Incorporation of citronellic acid (CA) into egg-yolk phosphatidylcho...

  • Article
  • Open Access
12 Citations
3,397 Views
16 Pages

Citronellal Attenuates Oxidative Stress–Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus

  • Ya-Ling Yin,
  • Huan-Huan Wang,
  • Zi-Chen Gui,
  • Shan Mi,
  • Shuang Guo,
  • Yue Wang,
  • Qian-Qian Wang,
  • Rui-Zhu Yue,
  • Lai-Biao Lin and
  • Peng Li
  • + 8 authors

14 November 2022

In type 2 diabetes mellitus (T2DM), oxidative stress induces endothelial dysfunction (ED), which is closely related to the formation of atherosclerosis. However, there are few effective drugs to prevent and cure it. Citronellal (CT) is an aromatic ac...

  • Article
  • Open Access
69 Citations
5,411 Views
11 Pages

Citronellal Exerts Its Antifungal Activity by Targeting Ergosterol Biosynthesis in Penicillium digitatum

  • Qiuli OuYang,
  • Yangmei Liu,
  • Okwong Reymick Oketch,
  • Miaoling Zhang,
  • Xingfeng Shao and
  • Nengguo Tao

29 May 2021

Ergosterol (ERG) is a potential target for the development of antifungal agents against Penicillium digitatum, the pathogen of green mold in citrus fruits. This study examined the mechanism by which citronellal, a typical terpenoid of Cymbopogon nard...

  • Article
  • Open Access
9 Citations
3,119 Views
20 Pages

1 April 2023

Major concerns of carbon dioxide (CO2) sequestration in subsurface formations are knowledge of the well injectivity and gas storage capacity of the formation, the CO2 pressure and saturation plume extensions during and after injection, and the risks...

  • Article
  • Open Access
11 Citations
3,779 Views
13 Pages

Engineering of Yeast Old Yellow Enzyme OYE3 Enables Its Capability Discriminating of (E)-Citral and (Z)-Citral

  • Tairan Wang,
  • Ran Wei,
  • Yingting Feng,
  • Lijun Jin,
  • Yunpeng Jia,
  • Duxia Yang,
  • Zuonan Liang,
  • Mengge Han,
  • Xia Li and
  • Xiangxian Ying
  • + 1 author

20 August 2021

The importance of yeast old yellow enzymes is increasingly recognized for direct asymmetric reduction of (E/Z)-citral to (R)-citronellal. As one of the most performing old yellow enzymes, the enzyme OYE3 from Saccharomyces cerevisiae S288C exhibited...

  • Article
  • Open Access
4 Citations
4,808 Views
11 Pages

3 August 2019

A chiral derivatizing agent (CDA) with the aldehyde function has been widely used in discriminating chiral amines because of the easy formation of imines under mild conditions. There is a preference for the use of cyclic aldehydes as a CDA since thei...

  • Article
  • Open Access
2 Citations
1,623 Views
21 Pages

In Vivo and In Vitro Grown Lemon-Scented Gum as a Source of Nematicidal Essential Oil Compounds

  • Jorge M. S. Faria,
  • Gonçalo Pereira,
  • Ana Cristina Figueiredo and
  • Pedro Barbosa

20 June 2025

Corymbia citriodora is a eucalypt tree of significant economic value due to its essential oils (EOs), rich in citronellal, citronellol, and other oxygenated monoterpenes with diverse biological activities. Its EOs show potential for the formulation o...

  • Article
  • Open Access
7 Citations
3,786 Views
11 Pages

This study aimed to evaluate the extraction of Corymbia citriodora (Hook.) K.D.Hill and L.A.S.Johnson essential oil by steam distillation under reduced pressure. Yield and composition of the essential oils obtained at different system pressures were...

  • Article
  • Open Access
21 Citations
4,455 Views
14 Pages

22 April 2021

Previous studies revealed the impact growing location has on the quantity and quality of essential oils derived from numerous Citrus spp., except on the kaffir lime. This study aims to analyze the relationship shared by agroclimatic variables and soi...

  • Communication
  • Open Access
19 Citations
3,886 Views
8 Pages

Composition of the Essential Oil and Insecticidal Activity of Launaea taraxacifolia (Willd.) Amin ex C. Jeffrey Growing in Nigeria

  • Moses S. Owolabi,
  • Akintayo L. Ogundajo,
  • Azeezat O. Alafia,
  • Kafayat O. Ajelara and
  • William N. Setzer

11 July 2020

The rice weevil (Sitophilus oryzae) is a pest of stored grain products such as rice, wheat, and corn. Essential oils represent a green environmentally-friendly alternative to synthetic pesticides for controlling stored-product insect pests. Launaea t...

  • Article
  • Open Access
8 Citations
2,749 Views
17 Pages

Essential Oil Volatiles as Sustainable Antagonists for the Root-Knot Nematode Meloidogyne ethiopica

  • Jorge M. S. Faria,
  • Leidy Rusinque,
  • Tomás Cavaco,
  • João C. Nunes and
  • Maria L. Inácio

23 July 2023

Climate change is prompting a shift of tropical pests to locations with a previously lower probability of invasion. This is the case for root-knot nematodes, Meloidogyne sp., particularly of the tropical group. Among them, M. ethiopica is now conside...

  • Review
  • Open Access
36 Citations
9,754 Views
13 Pages

9 July 2021

Lemon oils are amongst the highest volume and most frequently traded of the flavor and fragrance essential oils. Citronellal and citral are considered the key components responsible for the lemon note with citral (neral + geranial) preferred. Of the...

  • Article
  • Open Access
24 Citations
4,678 Views
10 Pages

16 April 2021

In this study, Magnolia citrata Noot and Chalermglin (Magnoliaceae) essential oil (MCEO) was evaluated for insecticidal activity against the yellow fever mosquito Aedes aegypti and attractant activity for the Mediterranean fruit fly Ceratitis capitat...

  • Article
  • Open Access
33 Citations
11,712 Views
12 Pages

Effects of Inhaled Citronella Oil and Related Compounds on Rat Body Weight and Brown Adipose Tissue Sympathetic Nerve

  • Irmanida Batubara,
  • Irma H. Suparto,
  • Siti Sa’diah,
  • Ryunosuke Matsuoka and
  • Tohru Mitsunaga

12 March 2015

Citronella oil is one of the most famous Indonesian essential oils, having a distinctive aroma. As with other essential oils, it is crucial to explore the effects of inhalation of this oil. Therefore, the aim of this research was to elucidate the eff...

  • Article
  • Open Access
20 Citations
4,931 Views
18 Pages

Kaffir lime has been widely researched for use as an essential oil, alongside its main function as an Asian spice, due to the needs of numerous industries. A meta-analysis was used to summarize the variation in yield and main components of kaffir lim...

  • Article
  • Open Access
3 Citations
3,885 Views
21 Pages

This study explores the chemical composition and synergistic anti-fungal properties of essential oils from the aerial parts of Satavari (Asparagus racemosus Willd.), Dill (Anethum graveolens L.), and lemongrass (Cymbopogon citratus Stapf), along with...

  • Article
  • Open Access
61 Citations
10,119 Views
14 Pages

The Effect of Citrus Essential Oils and Their Constituents on Growth of Xanthomonas citri subsp. citri

  • Hossein Mirzaei-Najafgholi,
  • Saeed Tarighi,
  • Morteza Golmohammadi and
  • Parissa Taheri

Citrus bacterial canker (CBC) caused by Xanthomonas citri subsp. citri (Xcc), is the most devastating of the citrus diseases worldwide. During our study, we found that Essential oils (EOs) of some citrus cultivars are effective on Xcc. Therefore, it...

  • Article
  • Open Access
16 Citations
6,682 Views
12 Pages

Behavioral Responses of the Common Bed Bug to Essential Oil Constituents

  • María A. González-Morales,
  • Martín Terán and
  • Alvaro Romero

21 February 2021

Botanical-derived pesticides have arisen as an attractive alternative to synthetic insecticides to effectively manage infestations of bed bugs (Cimex lectularius L.). While information on contact, residual, and fumigant toxicity of plant-essential oi...

  • Feature Paper
  • Article
  • Open Access
5 Citations
3,021 Views
16 Pages

10 July 2020

The large scale and complexity of Carbon, Capture, Storage (CCS) projects necessitates time and cost saving strategies to strengthen investment and widespread deployment of this technology. Here, we successfully demonstrate a novel geologic site char...

  • Article
  • Open Access
17 Citations
2,869 Views
12 Pages

21 February 2023

The volatile metabolites of Salvia sclarea, Rosmarinus officinalis, Thymus serpyllum, Mentha spicata, Melissa officinalis, Origanum majorana, Mentha piperita, Ocimum basilicum and Lavandula angustifolia were determined by gas chromatography–mas...

  • Article
  • Open Access
13 Citations
4,115 Views
13 Pages

Cascading Old Yellow Enzyme, Alcohol Dehydrogenase and Glucose Dehydrogenase for Selective Reduction of (E/Z)-Citral to (S)-Citronellol

  • Yunpeng Jia,
  • Qizhou Wang,
  • Jingjing Qiao,
  • Binbin Feng,
  • Xueting Zhou,
  • Lijun Jin,
  • Yingting Feng,
  • Duxia Yang,
  • Chenze Lu and
  • Xiangxian Ying

30 July 2021

Citronellol is a kind of unsaturated alcohol with rose-like smell and its (S)-enantiomer serves as an important intermediate for organic synthesis of (-)-cis-rose oxide. Chemical methods are commonly used for the synthesis of citronellol and its (S)-...

  • Article
  • Open Access
9 Citations
2,705 Views
12 Pages

Susceptibility of Amblyomma sculptum, Vector of Rickettsia rickettsii, Ticks from a National Park and an Experimental Farm to Different Synthetic Acaricides

  • Ennya Rafaella Neves Cardoso,
  • Stephani Félix Carvalho,
  • Sarah Alves Dias,
  • Rayane Almeida Santos,
  • Mariana Avelar Tavares,
  • Lucianne Cardoso Neves,
  • Warley Vieira de Freitas Paula,
  • Gracielle Teles Pádua,
  • Nicolas Jalowitzki de Lima and
  • Felipe da Silva Krawczak
  • + 8 authors

31 October 2023

Amblyomma sculptum is a relevant tick species from a One Health perspective, playing an important role as a vector of Rickettsia rickettsii, the main agent of spotted fever rickettsiosis in Brazil. In this study, we evaluated the susceptibility of tw...

  • Article
  • Open Access
16 Citations
2,887 Views
20 Pages

HS-SPME/GC×GC-TOFMS-Based Flavoromics and Antimicrobial Properties of the Aroma Components of Zanthoxylum motuoense

  • Wei Gu,
  • Yinghuan Wei,
  • Xianjie Fu,
  • Ronghui Gu,
  • Junlei Chen,
  • Junyou Jian,
  • Liejun Huang,
  • Chunmao Yuan,
  • Wenling Guan and
  • Xiaojiang Hao

31 May 2023

Zanthoxylum motuoense Huang, native to Tibet, China, is a newly discovered Chinese prickly ash, which, recently, has increasingly attracted the attention of researchers. In order to understand its volatile oil compositions and flavor characteristics,...

  • Article
  • Open Access
13 Citations
11,096 Views
20 Pages

Development of a Nanotechnology Matrix-Based Citronella Oil Insect Repellent to Obtain a Prolonged Effect and Evaluation of the Safety and Efficacy

  • Celio Takashi Higuchi,
  • Caroline Cianga Sales,
  • Newton Andréo-Filho,
  • Tereza Silva Martins,
  • Helena Onishi Ferraz,
  • Yasmin Rosa Santos,
  • Patricia Santos Lopes,
  • Jeffrey Ernest Grice,
  • Heather Ann Elizabeth Benson and
  • Vania Rodrigues Leite-Silva

4 January 2023

Mosquito-borne diseases affect millions of people worldwide each year, and the use of a topically applied insect repellent is an economically viable preventative health practice. The general objective of this work was to encapsulate citronella oil (C...

  • Article
  • Open Access
36 Citations
9,739 Views
11 Pages

Medicinal Properties of Lilium candidum L. and Its Phytochemicals

  • Michele Zaccai,
  • Ludmila Yarmolinsky,
  • Boris Khalfin,
  • Arie Budovsky,
  • Jonathan Gorelick,
  • Arik Dahan and
  • Shimon Ben-Shabat

29 July 2020

Lilium candidum L., known as Madonna, meadow, or white lily, is a bulbous plant from the Liliaceae family, originating in the Middle East. L. candidum has been abundantly used in folk medicine since ancient times to relieve a variety of ailments, inc...

  • Communication
  • Open Access
4 Citations
6,698 Views
7 Pages

Organocatalyzed Intramolecular Carbonyl-Ene Reactions

  • Heidi A. Dahlmann,
  • Amanda J. McKinney,
  • Maria P. Santos and
  • Lindsey O. Davis

An organocatalyzed intramolecular carbonyl-ene reaction was developed to produce carbocyclic and heterocyclic 5- and 6-membered rings from a citronellal-derived trifluoroketone and a variety of aldehydes. A phosphoramide derivative was found to promo...

  • Article
  • Open Access
42 Citations
7,303 Views
19 Pages

Composition and Bioactivity of Essential Oil from Citrus grandis (L.) Osbeck ‘Mato Peiyu’ Leaf

  • Mei-Lin Tsai,
  • Cai-Di Lin,
  • Keh Ai Khoo,
  • Mei-Ying Wang,
  • Tsang-Kuei Kuan,
  • Wei-Chao Lin,
  • Ya-Nan Zhang and
  • Ya-Ying Wang

5 December 2017

‘Mato Peiyu’ pomelo (Citrus grandis (L.) Osbeck ‘Mato Peiyu’) leaves from pruning are currently an agricultural waste. The aim of this study was to isolate essential oils from these leaves through steam distillation (SD) and solvent-free microwave ex...

  • Article
  • Open Access
3 Citations
2,702 Views
11 Pages

Evaluation of Cryogen-Free Thermal Modulation-Based Enantioselective Comprehensive Two-Dimensional Gas Chromatography for Stereo-Differentiation of Monoterpenes in Citrus spp. Leaf Oils

  • Haneen Ibrahim Al Othman,
  • Atiqah Zaid,
  • Francesco Cacciola,
  • Zhijun Zhao,
  • Xiaosheng Guan,
  • Jalal T. Althakafy and
  • Yong Foo Wong

1 February 2023

This study evaluates the applicability of enantioselective gas chromatography (eGC) and enantioselective comprehensive two-dimensional gas chromatography (eGC×GC) coupled with flame ionization detection for the stereospecific analysis of design...

  • Communication
  • Open Access
32 Citations
5,740 Views
11 Pages

In Vitro Evaluation of Sub-Lethal Concentrations of Plant-Derived Antifungal Compounds on FUSARIA Growth and Mycotoxin Production

  • Caterina Morcia,
  • Giorgio Tumino,
  • Roberta Ghizzoni,
  • Assetou Bara,
  • Nesrine Salhi and
  • Valeria Terzi

Phytopathogenic fungi can lead to significant cereal yield losses, also producing mycotoxins dangerous for human and animal health. The fungal control based on the use of synthetic fungicides can be complemented by "green" methods for crop protection...

  • Article
  • Open Access
37 Citations
5,808 Views
14 Pages

Citral-Containing Essential Oils as Potential Tyrosinase Inhibitors: A Bio-Guided Fractionation Approach

  • Francesca Capetti,
  • Massimo Tacchini,
  • Arianna Marengo,
  • Cecilia Cagliero,
  • Carlo Bicchi,
  • Patrizia Rubiolo and
  • Barbara Sgorbini

13 May 2021

Excessive melanin production causes serious dermatological conditions as well as minor aesthetic problems (i.e., freckles and solar lentigo). The downregulation of tyrosinase is a widespread approach for the treatment of such disorders, and plant ext...

  • Article
  • Open Access
7 Citations
6,841 Views
13 Pages

Identification of Citronella Oil Fractions as Efficient Bio-Additive for Diesel Engine Fuel

  • Noor Fitri,
  • Rahmat Riza,
  • Muhammad Kurnia Akbari,
  • Nada Khonitah,
  • Rifaldi Lutfi Fahmi and
  • Is Fatimah

14 February 2022

Escalation fuel consumption occurs in various regions of the world. However, world oil reserves decline from year to year so that it becomes scarce and causes oil prices to surge up. This problem can be solved by saving fuel consumption. One method o...

  • Article
  • Open Access
2,167 Views
27 Pages

Sensing of Volatile Organic Compounds by Haller’s Structure in Ixodidae Tick: Electroscutumography and Olfactometric Bioassay

  • Alivia Mandal,
  • Bishwajeet Paul,
  • Biswanath Bhowmik,
  • Raja Reddy Gundreddy,
  • Adolat U. Mirzaieva and
  • Kakali Bhadra

4 June 2025

Background: Chemosensation in ticks opens a novel and unique field for scientific research. This study highlights ticks’ chemosensory system to comprehend its host-searching behavior and other integrated chemistry and biology involving Haller&r...

  • Article
  • Open Access
77 Citations
11,392 Views
11 Pages

Seasonal Variation in the Chemical Composition and Antimicrobial Activity of Volatile Oils of Three Species of Leptospermum (Myrtaceae) Grown in Brazil

  • Antonio Jacinto Demuner,
  • Luiz Claudio Almeida Barbosa,
  • Cassia Gonçalves Magalhaes,
  • Cleber Jose Da Silva,
  • Celia Regina Alvares Maltha and
  • Antonio Lelis Pinheiro

26 January 2011

This study investigates the seasonal variation of three species of Leptospermum (Myrtaceae) grown in Brazil. The chemical composition of the volatile oils of L. flavescens and L. petersonii did not show any significant seasonal variation in the major...

  • Article
  • Open Access
74 Citations
7,778 Views
10 Pages

Typical Monoterpenes as Insecticides and Repellents against Stored Grain Pests

  • Suelen L. Reis,
  • Anieli G. Mantello,
  • Jeferson M. Macedo,
  • Erica A. Gelfuso,
  • Cássio P. Da Silva,
  • Ana L. Fachin,
  • Alexandre M. Cardoso and
  • Rene O. Beleboni

23 February 2016

Five monoterpenes naturally occurring in essential oils were tested for their insecticidal and repellent activities against the bruchid beetle Callosobruchus maculatus and the maize weevil Sitophilus zeamais. The monoterpenes were highly efficient as...

  • Communication
  • Open Access
33 Citations
5,341 Views
11 Pages

12 September 2019

Volatile compounds in flowers of Rhododendron delavayi, R. agastum, R. annae, and R. irroratum were analyzed using comprehensive two-dimensional gas chromatography-mass spectrometry (GC×GC) coupled with high-resolution quadrupole time-of-flight...

  • Article
  • Open Access
30 Citations
7,206 Views
13 Pages

31 January 2018

Phytochemical characters were evaluated in a five-year-old lemon balm collection consisting of 15 and 13 subspecies officinalis and altissima accessions, respectively. Stems were lower in essential oil than leaves. First cut leaves (June) gave more o...

  • Review
  • Open Access
122 Citations
21,086 Views
25 Pages

Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review

  • Gabriela Petrisor,
  • Ludmila Motelica,
  • Luminita Narcisa Craciun,
  • Ovidiu Cristian Oprea,
  • Denisa Ficai and
  • Anton Ficai

Melissa officinalis is a medicinal plant rich in biologically active compounds which is used worldwide for its therapeutic effects. Chemical studies on its composition have shown that it contains mainly flavonoids, terpenoids, phenolic acids, tannins...

  • Review
  • Open Access
43 Citations
8,807 Views
21 Pages

29 January 2022

Metabolic disorders like diabetes mellitus, hypertension, dyslipidemia, and obesity are major medical problems globally. The incidence of these disorders has increased tremendously in recent years. Studies have demonstrated that plants with antioxida...

  • Review
  • Open Access
201 Citations
39,760 Views
23 Pages

Lemongrass Essential Oil Components with Antimicrobial and Anticancer Activities

  • Mohammad Mukarram,
  • Sadaf Choudhary,
  • Mo Ahamad Khan,
  • Palmiro Poltronieri,
  • M. Masroor A. Khan,
  • Jamin Ali,
  • Daniel Kurjak and
  • Mohd Shahid

22 December 2021

The prominent cultivation of lemongrass (Cymbopogon spp.) relies on the pharmacological incentives of its essential oil. Lemongrass essential oil (LEO) carries a significant amount of numerous bioactive compounds, such as citral (mixture of geranial...

  • Article
  • Open Access
9 Citations
3,724 Views
13 Pages

Evaluation of the In Vitro Antiparasitic Effect of the Essential Oil of Cymbopogon winterianus and Its Chemical Composition Analysis

  • Pedro Silvino Pereira,
  • Carlos Vinicius Barros Oliveira,
  • Ana Josicleide Maia,
  • Maria Celeste Vega-Gomez,
  • Miriam Rolón,
  • Cathia Coronel,
  • Antônia Eliene Duarte,
  • Henrique Douglas Melo Coutinho,
  • Abolghasem Siyadatpanah and
  • Teresinha Gonçalves Silva
  • + 3 authors

25 April 2022

Cymbopogon winterianus, known as “citronella grass”, is an important aromatic and medicinal tropical herbaceous plant. The essential oil of C. winterianus (EOCw) is popularly used to play an important role in improving human health due to...

  • Review
  • Open Access
49 Citations
14,977 Views
11 Pages

Essential Oils from the Malaysian Citrus (Rutaceae) Medicinal Plants

  • Siti Nur Atiqah Md Othman,
  • Muhammad Aizam Hassan,
  • Lutfun Nahar,
  • Norazah Basar,
  • Shajarahtunnur Jamil and
  • Satyajit D. Sarker

This review article appraises the extraction methods, compositions, and bioactivities of the essential oils from the Citrus species (family: Rutaceae) endemic to Malaysia including C. aurantifolia, C. grandis, C. hystrix, and C. microcarpa. Generally...

  • Feature Paper
  • Article
  • Open Access
24 Citations
28,414 Views
23 Pages

Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments

  • Aldar A. Munkuev,
  • Evgenii S. Mozhaitsev,
  • Arina A. Chepanova,
  • Evgeniy V. Suslov,
  • Dina V. Korchagina,
  • Olga D. Zakharova,
  • Ekaterina S. Ilina,
  • Nadezhda S. Dyrkheeva,
  • Alexandra L. Zakharenko and
  • Olga I. Lavrik
  • + 3 authors

Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a promising target for anticancer therapy due to its ability to counter the effects topoisomerase 1 (Top1) poison, such as topotecan, thus, decreasing their efficacy. Compounds containing adamantane and monot...

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